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DBA/Z mice

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2024

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

318

Peptides

Inhibitory Antibodies

339

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5975

Z-Leu-Leu-Leu-fluoromethyl ketone Z-LLL-FMK	Cathepsin SARS-CoV	Infection
Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) is a cysteine protease inhibitor. Z-Leu-Leu-Leu-fluoromethyl ketone inhibits SARS infection. Z-Leu-Leu-Leu-fluoromethyl ketone also protects mice against a T. crassiceps challenge .

HY-NP0154

Dolichos Biflorus Agglutinin (Rhodamine) DBA (Rhodamine)	Fluorescent Dye	Others
Dolichos Biflorus Agglutinin (DBA) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Dolichos Biflorus Agglutinin (DBA) Rhodamine is a biological material or organic compound that can be used in life science research .

HY-NP0176

Dolichos Biflorus Agglutinin (Biotinylated) DBA，Biotinylated	Fluorescent Dye	Others
Dolichos Biflorus Agglutinin (DBA，Biotinylated) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Dolichos Biflorus Agglutinin (DBA，Biotinylated) is a biological material or organic compound that can be used in life science research .

HY-NP098

Dolichos Biflorus Agglutinin (Fluorescein) DBA (Fluorescein)	Fluorescent Dye	Others
Dolichos Biflorus Agglutinin (DBA) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Dolichos Biflorus Agglutinin (DBA) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-128960

DBA-DM4	Drug-Linker Conjugates for ADC	Cancer
DBA-DM4 is a agent-linker conjugate composed of a potent a tubulin inhibitor DM1 and a linker SPDP to make antibody agent conjugate (ADC) .

HY-107842

(Z)-JIB-04

NSC693627
Others Cancer

(Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis .
HY-P10004

Z-Ala-Ala-Asp-CMK

Z-AAD-CMK
Caspase Inflammation/Immunology

Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor .

(Z)-JIB-04 NSC693627	Others	Cancer
(Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis .

Z-Ala-Ala-Asp-CMK Z-AAD-CMK	Caspase	Inflammation/Immunology
Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor .

HY-138096

Z-LLF-CHO Z-Leu-Leu-Phe-CHO	Proteasome	Cancer
Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) is a potent inhibitor of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (K_i = 460 nM). Z-LLF-CHO is also a NF-κB nuclear translocation inhibitor .

HY-101297

Z-IETD-FMK 40+ Cited Publications Z-IE(OMe)TD(OMe)-FMK	Caspase	Cancer
Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective and cell permeable caspase-8 inhibitor . Z-IETD-FMK is also a granzyme B inhibitor .

HY-P10001

Z-IETD-pNA Z-Ile-Glu-Thr-Asp-pNA	Caspase	Cancer
Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .

HY-16658

Z-VAD(OMe)-FMK 155+ Cited Publications Z-Val-Ala-Asp(OMe)-FMK	Caspase	Cancer
Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable and irreversible pan-caspase inhibitor . Z-VAD(OMe)-FMK is an ubiquitin carboxy-terminal hydrolase L1 (UCHL1) inhibitor. Z-VAD(OMe)-FMK irreversibly modifies UCHL1 by targeting the active site of UCHL1 .

HY-P4427

Z-VAN-AMC

Fluorescent Dye Others

Z-VAN-AMC is a fluorogenic substrate. Z-VAN-AMC can be hydrolysed by a phytophagous mite of legumain-like activity .

Z-VAN-AMC	Fluorescent Dye	Others
Z-VAN-AMC is a fluorogenic substrate. Z-VAN-AMC can be hydrolysed by a phytophagous mite of legumain-like activity .

HY-141867

Z-FF-FMK Z-Phe-Phe-FMK	Cathepsin	Neurological Disease
Z-FF-FMK is a selective cathepsin-L inhibitor. Z-FF-FMK can prevent β-amyloid to induce apoptotic changes such as activation of caspase-3, cleavage of the DNA repair enzyme, poly-ADP ribose polymerase, and DNA fragmentation .

HY-137286

Z-Leu-Leu-Glu-βNA Z-Leu-Leu-Glu-β-naphthylamide	Proteasome	Others
Z-Leu-Leu-Glu-βNA (Z-Leu-Leu-Glu-β-naphthylamide) is a substrate for determination of the glutamylpeptidyl-peptide hydrolase activity of the 20S proteasome .

HY-P10322

Z-IETD-R110	Fluorescent Dye	Cancer
Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .

HY-P4392

Z-VAD-AMC

Caspase Others

Z-VAD-AMC is a substrate of caspase-9 .
HY-137521

Z-PDLDA-NHOH

MMP Others

Z-PDLDA-NHOH is a potent and specific inhibitor of vertebrate collagenase .

Z-VAD-AMC	Caspase	Others
Z-VAD-AMC is a substrate of caspase-9 .

Z-PDLDA-NHOH	MMP	Others
Z-PDLDA-NHOH is a potent and specific inhibitor of vertebrate collagenase .

HY-P4295

Z-Phe-Ala-diazomethylketone PADK	Cathepsin γ-secretase	Neurological Disease
Z-Phe-Ala-diazomethylketone binds directly to Aβ42 monomers and small oligomers. Z-Phe-Ala-diazomethylketone inhibits the formation of Aβ42 dodecamers and inhibits Aβ42 fibril formation in the solution. Z-Phe-Ala-diazomethylketone has the potential for neurodegenerative disorders research .

HY-W011374

Z-Gly-Osu

Amino Acid Derivatives Others

Z-Gly-Osu is a Glycine (HY-Y0966) derivative .
HY-P4293

Z-Leu-Tyr-Chloromethylketone

Proteasome Cathepsin Others

Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor .
HY-P5999

Z-FG-NHO-Bz

Cathepsin Cancer

Z-FG-NHO-Bz is a selective cathepsin inhibitor .

Z-Gly-Osu	Amino Acid Derivatives	Others
Z-Gly-Osu is a Glycine (HY-Y0966) derivative .

Z-Leu-Tyr-Chloromethylketone	Proteasome Cathepsin	Others
Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor .

Z-FG-NHO-Bz	Cathepsin	Cancer
Z-FG-NHO-Bz is a selective cathepsin inhibitor .

HY-P4217

Z-Gly-Pro-Arg-AMC hydrochloride	Cathepsin	Others
Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity .

HY-P0019B

Z-Gly-Gly-Arg-AMC TFA	Fluorescent Dye	Others
Z-Gly-Gly-Arg-AMC TFA is the TFA salt form of Z-Gly-Gly-Arg-AMC (HY-P0019). Z-Gly-Gly-Arg-AMC TFA is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) .

HY-129867

Z-Leu-Leu-Leu-AMC

Z-LLL-AMC
Proteasome Others

Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome .
HY-P4369

Z-Arg-Arg-AMC

Cathepsin Others

Z-Arg-Arg-AMC is a selective substrate of cathepsin B .
HY-134434

Z-Arg-Arg-AMC hydrochloride

Cathepsin Others

Z-Arg-Arg-AMC hydrochloride is a selective substrate of cathepsin B .

Z-Leu-Leu-Leu-AMC Z-LLL-AMC	Proteasome	Others
Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome .

Z-Arg-Arg-AMC	Cathepsin	Others
Z-Arg-Arg-AMC is a selective substrate of cathepsin B .

Z-Arg-Arg-AMC hydrochloride	Cathepsin	Others
Z-Arg-Arg-AMC hydrochloride is a selective substrate of cathepsin B .

HY-P10007

Z-Gly-Pro-Phe-Leu-CHO Z-GPFL-CHO	Proteasome	Cancer
Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor (K_i = 1.5 µM for branched chain amino acid preferring, 2.3 µM for small neutral amino acid preferring, and 40.5 µM for chymotrypsin-like activities; IC₅₀ = 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity) .

HY-P5125A

Z-Arg-SBzl TFA

PKC Others

Z-Arg-SBzl TFA is a substrate of both bovine and activated human protein C .
HY-P4500

Z-Arg-Arg-pNA

Cathepsin Others

Z-Arg-Arg-pNA is a substrate for cathepsin B and can be used to detect this enzyme activity .

Z-Arg-SBzl TFA	PKC	Others
Z-Arg-SBzl TFA is a substrate of both bovine and activated human protein C .

Z-Arg-Arg-pNA	Cathepsin	Others
Z-Arg-Arg-pNA is a substrate for cathepsin B and can be used to detect this enzyme activity .

HY-134961

Z-Ala-Arg-Arg-AMC Fluorogenic Proteasome Substrate; Z-ARR-AMC	Proteasome	Others
Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome .

HY-P1009

Z-YVAD-FMK

10+ Cited Publications

Caspase Cancer

Z-YVAD-FMK is a cell-permeable caspase-1 and -4 inhibitor with anti-inflammatory and anti-tumor activities .

Z-YVAD-FMK 10+ Cited Publications	Caspase	Cancer
Z-YVAD-FMK is a cell-permeable caspase-1 and -4 inhibitor with anti-inflammatory and anti-tumor activities .

HY-134454

Z-Pro-Pro-CHO	Parasite Prolyl Endopeptidase (PREP)	Infection
Z-Pro-Pro-CHO is a prolyl oligopeptidase inhibitor (_IC50: 0.16 μM and 0.01 μM for human and Schistosoma Mansoni prolyl oligopeptidase respectively) .

HY-P0019

Z-Gly-Gly-Arg-AMC	Fluorescent Dye	Cardiovascular Disease
Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

HY-P0019A

Z-Gly-Gly-Arg-AMC acetate 5+ Cited Publications	Fluorescent Dye	Others
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

HY-P0021

D-Lys(Z)-Pro-Arg-pNA

Chromozym Pca
Fluorescent Dye Others

D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a luminescent substrate of activated protein C (APC).

D-Lys(Z)-Pro-Arg-pNA Chromozym Pca	Fluorescent Dye	Others
D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a luminescent substrate of activated protein C (APC).

HY-15166

(E/Z)-Zotiraciclib 5 Publications Verification (E/Z)-TG02; (E/Z)-SB1317	CDK JAK FLT3	Cancer
(E/Z)-Zotiraciclib ((E/Z)-TG02) is a potent inhibitor of CDK2, JAK2 and FLT3 with IC₅₀s of 13, 73 and 56 nM, respectively. (E/Z)-Zotiraciclib effectively inhibits the proliferation of cancer cells, it can be used for the research of cancer .

HY-157457

Z21090	Phosphodiesterase (PDE)	Metabolic Disease
Z21090 (ZL40) is a potent inhibitor of PDE4 with the IC₅₀ value of 37.4 nM and oral bioavailability. Z21090 plays an important role in alcohol-related diseases research .

HY-113463

CE(20:5(5Z,8Z,11Z,14Z,17Z)

Endogenous Metabolite Metabolic Disease

CE(20:5(5Z,8Z,11Z,14Z,17Z) is an endogenous metabolite.

CE(20:5(5Z,8Z,11Z,14Z,17Z)	Endogenous Metabolite	Metabolic Disease
CE(20:5(5Z,8Z,11Z,14Z,17Z) is an endogenous metabolite.

HY-N0401A

(Z)-Ligustilide 2 Publications Verification	Bacterial	Infection Metabolic Disease
(Z)-Ligustilide is extracted from Ligusticum chuanxiong Hort, has antimicrobial and antifungal activity, exhibits an average antifungal score of 5.6 . (Z)-Ligustilide inhibits the expression of FATP5 and DGAT, inhibits fatty acid uptake and esterification in mice and has potential as therapeutics for nonalcoholic fatty liver disease (NAFLD) . (Z)-Ligustilide is also able to reactivate ERα, has epigenetic regulation, and is used in the study of tamoxifen-resistant breast cancer .

HY-113029

LysoPC(20:3(5Z,8Z,11Z))	Endogenous Metabolite	Metabolic Disease
LysoPC 20:3(5Z,8Z,11Z) is a lysophosphatidylcholine. LysoPC 20:3(5Z,8Z,11Z) can be used as a biomarker for acute aortic dissection .

HY-108398B

11(Z),14(Z),17(Z)-Eicosatrienoic acid	Endogenous Metabolite	Metabolic Disease
11(Z),14(Z),17(Z)-Eicosatrienoic acid is an unsaturated fatty acid that can maintain the continued replication of functional mitochondria in Saccharomyces cerevisiae (KD115) .

HY-114437

Fusion Inhibitory Peptide Z-D-Phe-Phe-Gly-OH; FIP; Virus Replication Inhibitory Peptide	Influenza Virus	Infection
Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) is a potent inhibitor of the virus replication, by inhibiting the membrane fusing activity of a viral glycoprotein .

HY-W013411

(E/Z)-Locostatin (E/Z)-UIC-1005	Others	Cancer
(E/Z)-Locostatin ((E/Z)-UIC-1005) is a racemic of Locostatin. Locostatin (UIC-1005) is a potent RKIP inhibitor. Locostatin binds Raf kinase inhibitor RKIP protein and disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. Locostatin inhibits cell proliferation and migration. Locostatin aggravates thioacetamide (HY-Y0698)-induced acute liver failure in mice .

HY-139507S

Z,Z-Dienestrol-d6

Isotope-Labeled Compounds Others

Z,Z-Dienestrol-d₆ is the deuterium labeled Z,Z-Dienestrol[1].

Z,Z-Dienestrol-d6	Isotope-Labeled Compounds	Others
Z,Z-Dienestrol-d₆ is the deuterium labeled Z,Z-Dienestrol[1].

HY-N7702

N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide	Wnt β-catenin	Metabolic Disease
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide is a macamide isolated from Maca (Lepidium meyenii Walp.) N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide induces mesenchymal stem cells osteogenic differentiation and consequent bone formation through activating the canonical Wnt/β‐catenin signaling pathway. N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide can be used for the research of osteoporosis .

HY-A0096A

(Z)-Iloprost

(Z)-Ciloprost; (Z)-ZK 36374
Others Cardiovascular Disease

(Z)-Iloprost ((Z)-Ciloprost; (Z)-ZK 36374) is a vasodilator that prevents heparin-induced platelet activation .

(Z)-Iloprost (Z)-Ciloprost; (Z)-ZK 36374	Others	Cardiovascular Disease
(Z)-Iloprost ((Z)-Ciloprost; (Z)-ZK 36374) is a vasodilator that prevents heparin-induced platelet activation .

HY-W013053

Dibenz[a,h]anthracene DBA; 1,2,5,6-Dibenzanthracene; Benzo[k]tetraphene	DNA/RNA Synthesis Apoptosis MDM-2/p53	Cancer
Dibenz[a,h]anthracene (DBA) is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms .

HY-113120

Stearidonic acid 6Z,9Z,12Z,15Z-Octadecatetraenoic acid	Endogenous Metabolite	Others
Stearidonic acid (6Z,9Z,12Z,15Z-Octadecatetraenoic acid) is an intermediate fatty acid in the biosynthetic pathway from α-linolenic acid to VLC ω-3 PUFA. The conversion efficiency of stearidonic acid is higher than that of alpha-linolenic acid. Increasing the intake of stearidonic acid can increase the content of eicosapentaenoic acid (EPA) in red blood cells. Stearidonic acid can also be isolated from methanolic extracts of the brown alga Brachyphyllum gracilis .

HY-138889

(8Z,14Z)-Eicosadienoic acid	Endogenous Metabolite	Metabolic Disease
8(Z),14(Z)-Eicosadienoic Acid is an ω-8 C20:2 fatty acid. The presence of 8(Z),14(Z)-eicosadienoic acid has been detected in human milk at a level of 0.19% (weight % total fatty acids).1 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators. The physiological effects of 8(Z),14(Z)-eicosadienoic acid are unstudied.

HY-149589

11(Z),14(Z)-Eicosadienoic acid	Leukotriene Receptor	Inflammation/Immunology
11(Z),14(Z)-Eicosadienoic acid is a unsaturated fattly acid that inhibits [ ³H] leukotriene B₄ (LTB₄) binding to pig neutrophil membranes with a K_i of 3 μM. 11(Z),14(Z)-Eicosadienoic acid has inflammatory activities .

Cat. No.	Product Name	Type

HY-P0019A

Z-Gly-Gly-Arg-AMC acetate Maximum Cited Publications 8 Publications Verification	Chromogenic Substrates
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

HY-134435

Z-Arg-AMC hydrochloride	Fluorescent Dyes/Probes
Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .

HY-P1986

Z-DEVD-AFC	Fluorescent Dyes/Probes
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .

HY-P0019

Z-Gly-Gly-Arg-AMC

Chromogenic Substrates

Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
HY-P0021

D-Lys(Z)-Pro-Arg-pNA

Chromozym Pca
Chromogenic Substrates

D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a luminescent substrate of activated protein C (APC).

HY-D1670

Z-Gly-Pro-AMC	Chromogenic Substrates
Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-amido-4-methylcoumarin (HY-D0027). (λ_ex=380 nm, λ_em=465 nm) .

HY-P2208

Z-IETD-AFC

Fluorescent Dyes/Probes

Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity .

HY-P3363

Z-DEVD-AMC	Chromogenic Substrates
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .

HY-P0021A

D-Lys(Z)-Pro-Arg-pNA diacetate

Spectrozyme PCa; Chromozym Pca diacetate
Chromogenic Substrates

D-Lys(Z)-Pro-Arg-pNA diacetate (Spectrozyme PCa) is a chromogenic substrate.

HY-D1523

Z-Arg-Arg-4MβNA triacetate	Fluorescent Dyes/Probes
Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λ_ex = 355 nm, λ_em = 430 nm) .

HY-D2203

BODIPY BDP4

Fluorescent Dyes/Probes

BODIPY BDP4 has ssuperb sonosensitivity and high SDT efficiency against cancer cells and tumors in tumor-bearing mice .

HY-D1535

IR 813 perchlorate	Fluorescent Dyes/Probes
IR 813 perchlorate is a near-infrared (NIR) fluorescent dye (Ex=815 nm, Em=840 nm) and can be used for visualizing regional lymph nodes in mice .

HY-153206G

MF59 (GMP)	Fluorescent Dye
MF59 (GMP) is a GMP grade MF59. MF59 is a immunologic adjuvant. MF59 significantly influnces immunogenicity of influenza vaccines. MF59 reduces the viral load in the lungs of challenged mice .

HY-D2095

Medical fluorophore 33	Fluorescent Dyes/Probes
Medical fluorophore 33 is a novel quinoline-isoquinoline salt. Medical fluorophore 33 exhibits a strong fluorescent signal, good microsomal stability and high biocompatibility in vivo. Medical fluorophore 33 has antitumor activity in colorectal cancer mice .

HY-D1066

NIR-Thiol dinitrobenzenesulfonate	Fluorescent Dyes/Probes
NIR-Thiol dinitrobenzenesulfonate has both absorption and emission in the NIR region. NIR-Thiol dinitrobenzenesulfonate responds to thiol with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-Thiol dinitrobenzenesulfonate is capable of imaging endogenously produced thiol in living cells and mice .

HY-D2279

NFL-NH2	Fluorescent Dyes/Probes
NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively .

HY-D1432

FITC-C6-DEVD-FMK	Fluorescent Dyes/Probes
FITC-C6-DEVD-FMK, a fluorescently labeled caspase-3 inhibitor, can be used for detection of active caspase-3 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. Z-DEVD-FMK is a specific caspase-3 inhibitor .

HY-D1433

FITC-C6-LEHD-FMK	Fluorescent Dyes/Probes
FITC-C6-LEHD-FMK, a fluorescently labeled caspase-9 inhibitor, can be used for detection of active caspase-9 in mammalian cells undergoing apoptosis. FITC-C6-LEHD-FMK provides a convenient means for sensitive detection of activated caspase-9 in living cells. Z-LEHD-FMK is a specific caspase-9 inhibitor .

HY-150236

FITC-labeled Tominersen sodium	Dyes
FITC-labeled Tominersen (sodium) is the Tominersen labeled with FITC. Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen improves survival and reduces brain atrophy in mice. Tominersen can be used for the research of Huntington’s disease (HD).

HY-D1460

Fluorescein Di-β-D-Glucuronide

Fluorescent Dyes/Probes

Fluorescein Di-β-D-Glucuronide, a fluorescent probe, can be utilized to non-invasively image the intestinal bacterial β-glucuronidase activity in nude mice. Fluorescein Di-β-D-Glucuronide-based imaging reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, which would facilitate pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies .

HY-15096

MKT-077 Maximum Cited Publications 8 Publications Verification FJ-776	Dyes
MKT-077 (FJ-776), a highly water-soluble mitochondrial dye, has significant antitumor activity . MKT-077 exhibits low cytotoxicity, and inhibits broad-spectrum human cancer cell lines (colon cancer, breast cancer, pancreatic cancer). MKT-077 inhibits the growth of tumor in nude mice enograft tumor model. Ex/Em=488/543 nm .

HY-149696

IR-Crizotinib

Dyes

IR-Crizotinib is a NF-κB-inducing kinase (NIK) inhibitor that crosses the blood-brain barrier and fluorescently localizes intracranial glioblastoma (GBM) in mice (IC₅₀=3.381 μM). IR-Crizotinib is conjugated from the near-infrared dye IR-786 and the NF-κB-inducing kinase (NIK) inhibitor Crizotinib. IR-Crizotinib can effectively inhibit the growth and invasion of glioma in vitro and in vivo and can be used in cancer research .

HY-D1065

NIR-H2O2	Fluorescent Dyes/Probes
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H₂O₂ with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H₂O₂ in living cells and mice .

HY-D1707

FDGlcU	Fluorescent Dyes/Probes
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm) .

HY-B1046

Clofazimine

5+ Cited Publications

Chromogenic Assays

Clofazimine is an orally-active anti-mycobacterial agent with a wide range of anti-mycobacterial activity including leprosy and tuberculosis. Clofazimine exerts anti-inflammatory activities and anti-tumor activities by interfering DNA replication and inhibiting IL2 (IC₅₀ = 1.10 ± 0.26 μM, Jurkat T) production. Clofazimine can be used in mycobacterial and cancer research .

HY-B1046R

Clofazimine (Standard)

Chromogenic Assays

Clofazimine (Standard) is the analytical standard of Clofazimine. This product is intended for research and analytical applications. Clofazimine is an orally-active anti-mycobacterial agent with a wide range of anti-mycobacterial activity including leprosy and tuberculosis. Clofazimine exerts anti-inflammatory activities and anti-tumor activities by interfering DNA replication and inhibiting IL2 (IC₅₀ = 1.10 ± 0.26 μM, Jurkat T) production. Clofazimine can be used in mycobacterial and cancer research .

Cat. No.	Product Name	Type

HY-W088147

Z-L-2-Nal-OH Z-2-Nal-OH	Biochemical Assay Reagents
Z-L-2-Nal-OH (Z-2-Nal-OH) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-NP0154

Dolichos Biflorus Agglutinin (Rhodamine) DBA (Rhodamine)	Native Proteins
Dolichos Biflorus Agglutinin (DBA) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Dolichos Biflorus Agglutinin (DBA) Rhodamine is a biological material or organic compound that can be used in life science research .

HY-NP0176

Dolichos Biflorus Agglutinin (Biotinylated) DBA，Biotinylated	Native Proteins
Dolichos Biflorus Agglutinin (DBA，Biotinylated) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Dolichos Biflorus Agglutinin (DBA，Biotinylated) is a biological material or organic compound that can be used in life science research .

HY-NP098

Dolichos Biflorus Agglutinin (Fluorescein) DBA (Fluorescein)	Native Proteins
Dolichos Biflorus Agglutinin (DBA) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Dolichos Biflorus Agglutinin (DBA) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-W127387

(Z,Z,Z)-17-Bromo-3,6,9-heptadecatriene (3Z,6Z,9Z)-17-Bromo-3,6,9-heptadecatriene	Biochemical Assay Reagents
(Z,Z,Z)-17-Bromo-3,6,9-Heptadecatriene is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P3466

Nisin Z

Biochemical Assay Reagents

Nisin Z is an antimicrobial and anti-inflammatory peptide. Nisin Z is effective against Gram-positive bacteria and fungi, such as C. albicans .

HY-121892

(Z)-KC02

Drug Delivery

(Z)-KC02 is an inhibitor of ABHD16A, the phosphatidylserine (PS) lipase that produces lyso-PS. Lysophosphatidylserine (lyso-PS) is a signaling lipid that regulates immune and neurological processes. It is associated with several neurological disorders such as retinitis pigmentosa and cataracts (PHARC). (Z)-KC02 depletes lyso-PS in lymphoblasts from PHARC subjects. (Z)-KC02 also reduces lyso-PS and lipopolysaccharide-induced cytokine production in macrophages and modulates lyso-PS metabolism in vivo .

HY-12056A

(E/Z)-BIX02189

Biochemical Assay Reagents

(E/Z)-BIX02189 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W011267

(Z)-Methyl icos-11-enoate	Biochemical Assay Reagents
(Z)-Methyl icos-11-enoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W008753

Z-L-Val-OH

N-Cbz-L-valine
Biochemical Assay Reagents

Z-L-Val-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W099645

(Z)-Methyl docos-13-enoate Methyl erucate	Biochemical Assay Reagents
(Z)-Methyl docos-13-enoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W017558

(Z)-Non-6-en-1-ol cis-6-nonen-1-ol	Biochemical Assay Reagents
(Z)-Non-6-en-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127486

N-3-oxo-Hexadec-11Z-enoyl-L-homoserine lactone	Biochemical Assay Reagents
N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-N8446

(E/Z)-Geranylacetone 6,10-Dimethylundeca-5,9-dien-2-one; Dihydropseudoionone	Biochemical Assay Reagents
(E/Z)-Geranylacetone is an organic compound commonly used as an ingredient in fragrances and fragrances. It can be used in some products such as perfumes, soaps and cosmetics, and can bring a fresh aromatic smell. In addition, the compound is used in some foods and pharmaceuticals, for example in candy, chewing gum and herbal remedies.

HY-115369

Methyl (13Z,16Z,19Z)-docosatrienoate

Biochemical Assay Reagents

cis-13,16,19-Docosatrienoic acid methyl ester is an ester form of docosatrienoic acid, a rare omega-3 fatty acid not found in the normal phospholipid polyunsaturated fatty acid pool Easily detectable, it inhibits the binding of [3H]-LTB4 to porcine neutrophils at a concentration of 5 μM. Methyl docosatrienoate is more fat-soluble than the free acid and may be more desirable than the free acid in some formulations.

HY-B2241A

Potassiumalum, for cell culture Aluminum potassium sulfate dodecahydrate, for cell culture	Cell Assay Reagents
Potassiumalum, for cell culture (Aluminum potassium sulfate dodecahydrate, for cell culture) is an egg white adjuvant that can induce allergic reactions in mice; it can also be used for bacterial staining. Potassiumalum, for cell culture is a biomaterial or organic compound that can be used in life science research .

HY-18651

(E/Z)-Rigosertib sodium (E/Z)-ON-01910 sodium	Biochemical Assay Reagents
Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127822

5,10,15-Triphenylcorrole (1Z,4Z,10Z,15Z)-5,10,15-Triphenyl-22,24-dihydro-21H-corri	Biochemical Assay Reagents
5,10,15-tris(phenyl)corrole is a corrole derivative used as a trianionic ligand for transition metals.

HY-W127320

(Z)-3-Nonen-1-ol

Biochemical Assay Reagents

Cis-3-nonen-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127824

5,10,15-Tris(4-nitrophenyl)corrole (5Z,9Z,14Z)-5,10,15-Tris(4-nitrophenyl)-22,24-dihydro-21H-corri	Biochemical Assay Reagents
5,10,15-tris(4-nitrophenyl)corrole is a corrole derivative used as a trianionic ligand for transition metals.

HY-W127504

Sodium ricinoleate	Biochemical Assay Reagents
(R,Z)-12-hydroxyoctadec-9-enoic acid, sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W100403

Choline tosylate Choline p-toluenesulfonate	Enzyme Substrates
Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG) .

HY-N7833

(all-Z)-6,9,12,15,18-Heneicosapentaenoic Acid

Heneicosapentaenoic acid

Biochemical Assay Reagents

Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the δ6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS.

HY-W127323

cis-9-Hexadecenol (Z)-Hexadec-9-en-1-ol	Biochemical Assay Reagents
cis-9-Hexadecenol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-158272

Penicillin/OVA	Biochemical Assay Reagents
Penicillin/OVA is a conjugate of penicillin and Ovalbumins (HY-W250978), that is utilized as an antigen in immunological research. Penicillin/OVA causes IgE-dependent anaphylactic response to penicillin in mice .

HY-NP003

Collagen, Type II, from bovine snout membrane Collagen, Type II, substrate for collagenase	Native Proteins
Collagen, Type II, from bovine snout membrane is a protein used to treat osteoarthritis. Type II collagen shows significant efficacy in improving the pain and inflammation of collagen induced arthritis in mice .

HY-153206G

MF59 (GMP)	Biochemical Assay Reagents
MF59 (GMP) is a GMP grade MF59. MF59 is a immunologic adjuvant. MF59 significantly influnces immunogenicity of influenza vaccines. MF59 reduces the viral load in the lungs of challenged mice .

HY-N8064

Methyl cis-15-tetracosenoate Methyl nervonate; Methyl (Z)-tetracos-15-enoate	Biochemical Assay Reagents
Methyl cis-15-tetracosenoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-D0873

HEPPS EPPS	Biochemical Assay Reagents
HEPPS (EPPS) is a buffering agent with the useful pH range from 7.3 ~ 8.7. HEPPS reduces Aβ-aggregate-induced memory deficits and rescues cognitive deficits in mice. EPPS is orally active and penetrates the blood-brain barrier .

HY-109506

DPPC 4 Publications Verification 129Y83	Drug Delivery
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-N1428A

Citric acid monohydrate 2 Publications Verification	Biochemical Assay Reagents
Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate causes renal toxicity in mice .

HY-W250113

Zymosan A Zymosan A from Saccharomyces cerevisiae	Biochemical Assay Reagents
Zymosan A (Zymosan A from Saccharomyces cerevisiae) is a TLR2 agonist, that targeting TLRs can prevent and suppress IR-induced intestinal injury. Zymosan A exhibits a significant radioprotective effect, and protects IR-induced intestinal injury in mice. Zymosan A promotes the regeneration of intestinal stem cells (ISCs), after IR injury .

HY-139298

L319 Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate	Drug Delivery
L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1 .

HY-145405

C12-200 5 Publications Verification	Drug Delivery
C12-200 is an ionizable cationic lipid and auxiliary lipid. C12-200 is commonly used for mRNA delivery. Administration of human erythropoietin (EPO) mRNA or factor VII siRNA increased and decreased serum factor VII levels, respectively, in LNPs mice containing C12-200 .

HY-B2201

Citric acid trisodium 3 Publications Verification Sodium citrate; Trisodium citrate anhydrous	Biochemical Assay Reagents
Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice .

HY-120978

Omega-3 arachidonic acid methyl ester

ω-3 Arachidonic acid methyl ester; (all-Z)-8,11,14,17-Eicosatetraenoic acid methyl ester

Biochemical Assay Reagents

omega-3 Arachidonic Acid methyl ester, mainly docosahexaenoic acid, eicosapentaenoic acid and α-Linoleic acid, represented by linoleic acid, is an essential dietary nutrient required for normal growth and development.Omega-3Methyl arachidonic acid is a rare fatty acid Omega-3Neutral fat-soluble form of arachidonic acid. Omega-3Fatty acids, as a group, were associated with reduced inflammation and autoimmune activity, as well as reduced thrombosis and platelet activation.

HY-125139

omega-3 Arachidonic acid ethyl ester

ω-3 Arachidonic acid ethyl ester; (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester

Biochemical Assay Reagents

omega-3 Arachidonic Acid ethyl ester is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.

HY-157252

CL4F8-6	Drug Delivery
CL4F8-6 is an ionizable cationic lipid with a pK_a of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .

HY-148859

AA-T3A-C12

Drug Delivery

AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .

HY-139414

Lysophosphatidylcholines 1 Publications Verification	Biochemical Assay Reagents
Lysophosphatidylcholines is an orally active lysolipid and a component of oxidized low density lipoprotein (LDL). Lysophosphatidylcholines induces cell injury, the production of IL-1β and apoptosis. Lysophosphatidylcholines has a proactive effect on sepsis .

HY-124187

Pinolenic acid ethyl ester

Ethyl pinolenate

Biochemical Assay Reagents

Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

Cat. No.	Product Name	Target	Research Area

HY-P99797

Pabinafusp alfa JR-141	Transferrin Receptor	Neurological Disease
Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice .

HY-P99199

Foralumab NI-0401	CD3	Inflammation/Immunology
Foralumab (NI-0401) is a potent, orally active human monoclonal antibody targeting the CD3. Foralumab modulates immune responses by human cells in NSG mice that were reconstituted with human hematopoietic stem cells .

HY-P99216

Ponezumab PF-04360365; RN 1219	EGFR	Neurological Disease
Ponezumab (PF-04360365) is a humanised anti-amyloid IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves performance in mice in various models of learning and memory. Ponezumab can be used in study of Alzheimer's disease .

HY-P99554

Topsalysin PRX-302	Inhibitory Antibodies	Cancer
Topsalysin is a PSA-activated protoxin, a pore-forming protein (synthetic proaerolysin) fusion protein with human prostate-specific antigen. Topsalysin has tumor suppression effect in mice modle .

HY-P99354

Bavunalimab Anti-Human CTLA4xLAG3	LAG-3	Inflammation/Immunology Cancer
Bavunalimab (Anti-Human CTLA4xLAG3) is a bispecific human anti-CTLA-4/LAG-3 monoclonal antibody. Bavunalimab activates T cells in NSG mice. Bavunalimab can be used for the research of cancer .

HY-P99908

Efineptakin alfa NT-17	Interleukin Related	Cancer
Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 ⁺ and CD8 ⁺ cells in both human and mice. Efineptakin alfa can be used for glioblastoma research .

HY-P99532

Urtoxazumab

HuVTm1.1; TMA-15
Inhibitory Antibodies Infection

Urtoxazumab (TMA-15) is a humanizedized monoclonal antibody against Shiga toxin (Stx) 2 .

HY-P99778

Ontuxizumab MORAb-004	Inhibitory Antibodies	Cancer
Ontuxizumab (MORAb-004) is a humanized IgG1/κ anti-endosialin (TEM-1 or CD248) monoclonal antibody with antitumor effects. Ontuxizumab can be used for the research of cancer .

HY-P99836

Cudarolimab IBI101	Orexin Receptor (OX Receptor)	Inflammation/Immunology Cancer
Cudarolimab (IBI101) is a completely human anti-OX40 (CD134, a co stimulating molecule expressed by activated immune cells) antibody. Cudarolimab inhibits the binding of OX40 to its ligand OX40L. Cudarolimab has antitumor activity and can be used in cancer related research .

HY-P99922

Encelimab	Inhibitory Antibodies	Cancer
Encelimab is an anti-LAG3 antibody. Encelimab blocks the interaction between LAG-3 and MHC II, and enhances T-cell activation. Encelimab alone or in combination with an anti-PD-1 antibody reduces tumor size in a lymphoma mice model (A20 cell xenograft) .

HY-P99212

Otlertuzumab

TRU-016
Inhibitory Antibodies Cancer

Otlertuzumab (TRU-016) is a humanized anti-CD37 monoclonal antibody that can be used for cancer research .

HY-P99721

Lutikizumab ABT-981	Interleukin Related	Inflammation/Immunology
Lutikizumab (ABT-981) is an anti-IL-1α and IL-1β dual variable domain immunoglobulin. Lutikizumab binds and inhibits IL-1α and IL-1β. Lutikizumab can be used for the research of osteoarthritis .

HY-P99265

Mapatumumab HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody	Inhibitory Antibodies	Cancer
Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer .

HY-P99814

Pavurutamab AMG-701	CD3	Inflammation/Immunology Cancer
Pavurutamab (AMG-701) is a bispecific T cell engager molecule that anti-CD3 and anti-B cell maturation antigens (BCMA). Pavurutamab has an extended half-life based on Pacanalotamab (HY-P99798). The Fc of Pavurutamab is coupled to molecules to improve pharmacokinetic parameters. Pavurutamab has potential applications in immune regulation and multiple myeloma (MM) .

HY-P99194

Evinacumab REGN1500	Inhibitory Antibodies	Cardiovascular Disease Metabolic Disease
Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia .

HY-108786

Asfotase alfa ENB-0040	Inhibitory Antibodies	Metabolic Disease
Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2 ^−/− knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP) .

HY-P99692

Lenercept p55TNF-R:Ig; Ro 45-2081; TNFR55-IgG1	TNF Receptor	Inflammation/Immunology
Lenercept (Ro 45-2081) is a recombinant fusion protein that consists of the soluble TNF-receptor (p55) linked to the Fc portion of human IgG1 .

HY-P99588

Stamulumab MYO-029	TGF-β Receptor	Metabolic Disease
Stamulumab (MYO-029) is a recombinant human IgG1λ antibody that binds to myostatin and neutralizes its activity by preventing binding to its endogenous high-affinity receptor ActRIIB. Stamulumab leads to muscle fiber hypertrophy and not hyperplasia in SCID mice. Stamulumab has the potential for Becker muscular dystrophy (BMD), facioscapulohumeral dystrophy (FSHD), and limb-girdle muscular dystrophy (LGMD) research .

HY-P99399

Semorinemab RG 6100; RO7105705; MTAU-9937A	Tau Protein	Neurological Disease
Semorinemab (RG 6100) is an anti-Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab binds with human Tau with a K_d value of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease .

HY-P99725

Marstacimab PF-06741086	Inhibitory Antibodies	Metabolic Disease
Marstacimab (PF-06741086) is an anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody. Marstacimab can be used for the research of hemophilia .

HY-P99583

Suvratoxumab MEDI4893	Bacterial	Infection Inflammation/Immunology
Suvratoxumab (MEDI4893) is a long-acting, high-affinity human anti-α-toxin monoclonal antibody (IgG1κ type). Suvratoxumab potently neutralizes α-toxin, a key S. aureus virulence factor. Suvratoxumab improves survival and reduces lung injury in an immunocompromised mice model of pneumonia. Suvratoxumab also enhances the antibacterial activity of Vancomycin (HY-B0671) or Linezolid (HY-10394) .

HY-P99156

Relatlimab BMS-986016	LAG-3	Cancer
Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC₅₀ value of 0.67 nM and LAG-3/FGL1 interaction with an IC₅₀ value of 0.019 nM. Relatlimab can be used in research of cancer .

HY-P99155

Zalutumumab	EGFR	Cancer
Zalutumumab is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab binds with IgG and its Fab fragment with EC₅₀s of 7 and 19 nM, respectively. Zalutumumab can be used for the research of cancer .

HY-P99414

Prezalumab AMG 557	Inhibitory Antibodies	Inflammation/Immunology
Prezalumab (AMG 557) is a humanized IgG2 monoclonal antibody targets ICOSL and BAFF. Prezalumab demonstrates beneficial activities on the arthritis of systemic lupus erythematosus. Prezalumab can be used for the research of sjogren's syndrome cutaneous lupus erythematosus, psoriasis and systemic lupus erythematosus (SLE) .

HY-P99345

Dostarlimab TSR-042	PD-1/PD-L1	Cancer
Dostarlimab (TSR-042) is a humanized anti-PD-1 monoclonal antibody. Dostarlimab binds with high affinity to human PD-1 and competitively inhibits its interaction with its ligands, PD-L1 and PD-L2, with IC₅₀s of 1.8 and 1.5 nM, respectively .

HY-P99351

Andecaliximab Anti-MMP9 Reference Antibody (andecaliximab)	MMP	Cancer
Andecaliximab is a recombinant chimeric IgG4 monoclonal antibody (mAb) targets matrix metalloproteinase 9 (MMP9). Andecaliximab shows the antifibrotic efficacy in idiopathic pulmonary fibrosis mouse models. Andecaliximab can be used for the research of gastric adenocarcinoma and idiopathic pulmonary fibrosis (IPF) .

HY-P99408

Oxelumab R 4930; huMAb OX 40L; Ro 49-89991	Interleukin Related	Inflammation/Immunology
Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma .

HY-P99699

Lesofavumab

MHAB5553A; RG70026
Influenza Virus Infection

Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody .

HY-P99680

Keliximab SB-210396; IDEC CE9.1	Interleukin Related	Cancer
Keliximab (SB-210396) is a chimeric human/macaque IgG1 anti-CD4 monoclonal antibody with a K_i value of 1.0 nM for soluble CD4. Keliximab blocks T cell proliferation and inhibits IL-2 production. Keliximab can be used for cancer research .

HY-P9987

Crizanlizumab	P-selectin	Cardiovascular Disease
Crizanlizumab is an anti-P-selectin monoclonal antibody. Crizanlizumab binds to P-selectin and blocks its interaction with P-selectin glycoprotein ligand 1 (PSGL-1). Crizanlizumab prevents vaso-occlusive crises (VOCs) and can be used for research of sickle cell disease .

HY-P99620

Firivumab CT-P22; CT120	Influenza Virus	Infection
Firivumab (CT-P22; CT120) is a human IgG1 monoclonal influenza A virus hemagglutinin (Anti-IAV HA) antibody. Firivumab is capable of neutralizing H1N1, H5N1, H6N1, H6N2, H8N4, H8N8, H9N2 and H12N7. Firivumab shows protection against H1N1 virus in mice .

HY-P99179

CTX-2026	Inhibitory Antibodies	Cancer
CTX-2026 is a fully human antibody that binds to CD277. CTX-2026 shows an anti-tumor effect on ovarian tumor models. CTX-2026 can be used for the research of cancer .

HY-P99222

Teplizumab MGA-031; PRV-031	CD3	Metabolic Disease
Teplizumab (MGA-031) is a Fc receptor non-binding anti-human CD3 monoclonal antibody. Teplizumab reduces the loss of beta-cell function. Teplizumab can be used in the research of type 1 diabetes .

HY-P99720

Luspatercept ACE-536; luspatercept–aamt	TGF-beta/Smad	Metabolic Disease
Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia .

HY-P9928

Alirocumab REGN 727; SAR 236553	PCSK9	Cardiovascular Disease
Alirocumab (REGN 727) is a human monoclonal antibody inhibitor of PCSK9. Alirocumab is a monoclonal antibody. Alirocumab has anti-inflammatory, antiangiogenic and antioxidant effects. Alirocumab can be used in the study of hypercholesterolemia .

HY-P99252

Itolizumab Anti-Human CD6 Recombinant Antibody	CD6	Infection Inflammation/Immunology
Itolizumab (Anti-Human CD6 Recombinant Antibody) is a humanized recombinant anti-CD6 monoclonal antibody (MAb) targeting the extracellular SRCR distal domain 1 of CD6. Itolizumab reduces T-cell proliferation and inhibits the production of pro-inflammatory cytokines, such as INF-γ, TNFα and IL-6. Itolizumab can be used in the research of psoriasis, rheumatoid arthritis (RA), COVID-19 .

HY-P99370

Landogrozumab LY2495655; Anti-GDF8 / Myostatin Reference Antibody (landogrozumab)	Inhibitory Antibodies	Inflammation/Immunology
Landogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0401A

(Z)-Ligustilide 2 Publications Verification	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Dicerothamnus rhinocerotis Plants Umbelliferae Disease Research Fields	Bacterial
(Z)-Ligustilide is extracted from Ligusticum chuanxiong Hort, has antimicrobial and antifungal activity, exhibits an average antifungal score of 5.6 . (Z)-Ligustilide inhibits the expression of FATP5 and DGAT, inhibits fatty acid uptake and esterification in mice and has potential as therapeutics for nonalcoholic fatty liver disease (NAFLD) . (Z)-Ligustilide is also able to reactivate ERα, has epigenetic regulation, and is used in the study of tamoxifen-resistant breast cancer .

HY-108398B

11(Z),14(Z),17(Z)-Eicosatrienoic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Endogenous Metabolite
11(Z),14(Z),17(Z)-Eicosatrienoic acid is an unsaturated fatty acid that can maintain the continued replication of functional mitochondria in Saccharomyces cerevisiae (KD115) .

HY-N7702

N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide	Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields	Wnt β-catenin
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide is a macamide isolated from Maca (Lepidium meyenii Walp.) N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide induces mesenchymal stem cells osteogenic differentiation and consequent bone formation through activating the canonical Wnt/β‐catenin signaling pathway. N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide can be used for the research of osteoporosis .

HY-113463

CE(20:5(5Z,8Z,11Z,14Z,17Z)	Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
CE(20:5(5Z,8Z,11Z,14Z,17Z) is an endogenous metabolite.

HY-113120

Stearidonic acid 6Z,9Z,12Z,15Z-Octadecatetraenoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Stearidonic acid (6Z,9Z,12Z,15Z-Octadecatetraenoic acid) is an intermediate fatty acid in the biosynthetic pathway from α-linolenic acid to VLC ω-3 PUFA. The conversion efficiency of stearidonic acid is higher than that of alpha-linolenic acid. Increasing the intake of stearidonic acid can increase the content of eicosapentaenoic acid (EPA) in red blood cells. Stearidonic acid can also be isolated from methanolic extracts of the brown alga Brachyphyllum gracilis .

HY-N0969

(Z)-Akuammidine 19-(Z)-Akuammidine; (Z)-Rhazine	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Disease Research Fields	Others
(Z)-Akuammidine ((Z)-Rhazine) is isolated from Gelsemium elegans .

HY-114610

13Z,16Z-Docosadienoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Free Fatty Acid Receptor
13Z,16Z-Docosadienoic acid, a ω-6 polyunsaturated fatty acid, possesses anti-borreliae effect. 13Z,16Z-Docosadienoic acid, as a long-chain fatty acid (LCFA), is a free fatty acid receptor 4 (FFAR4 or GPR120, a LCFA receptor) agonist .

HY-N1214A

(E/Z)-Squalene (E/Z)-Super Squalene; (E/Z)-AddaVax	Structural Classification Natural Products Animals Source classification	Apoptosis
(E/Z)-Squalene ((E/Z)-Super Squalene; (E/Z)-AddaVax) is a triterpenic compound. (E/Z)-Squalene accumulates and reduces liver cholesterol and triglycerides in the liver. (E/Z)-Squalen regulates the production of intracellular active oxidants (ROS) and induces apoptosis and necrosis in a concentration-and time-dependent manner .

HY-N12895

(Z,Z)-7,11-Hexadecadienyl acetate (Z,Z)-Gossyplure	Structural Classification Natural Products Animals Source classification	Others
(Z)-7,11-Hexadecadienyl acetate is a female sex pheromone used to attract male insects, isolated from Plutella xylostella .

HY-N12939

(11Z,13Z)-Hexadecadien-1-ol	Structural Classification Natural Products Animals Source classification	Others
(11Z,13Z)-Hexadecadien-1-ol is an insect sex pheromone attractive to male navel orangeworm moths (Amyeloistransitella), a secretion of the moth Z11, which can be isolated from Z13-16:Ald analogs .

HY-W230975

(E/Z)-Piperine (E/Z)-Bioperine; (E/Z)-1-Piperoylpiperidine	Structural Classification Alkaloids Piperidine Alkaloids Source classification Piperaceae Plants Piper nigrum Linn.	Others
(E/Z)-Piperine ((E/Z)-Bioperine) is an alkaloid with a pungent property. (E/Z)-Piperine shows anti-inflammation, immunomodulatory and anti-cancer, antispasmodic and anti-secretory effects. (E/Z)-Piperine demonstrates significant neuroprotective effect in Alzheimer’s disease and Parkinson’s disease .

HY-N6794

10Z-Hymenialdisine (Z)-Hymenialdisine; Hymenialdisine	Alkaloids Pyrrole Alkaloids Classification of Application Fields Animals Source classification Marine natural products Sponge Disease Research Fields Biological Pesticide Research Cancer Agricultural Research	AMPK VEGFR PDGFR
10Z-Hymenialdisine ((Z)-Hymenialdisine) is a natural bioactive pyrrole alkaloid. 10Z-Hymenialdisine is a pan kinase inhibitor, and has anticancer activities .

HY-N12920

(Z)-3-Dodecenyl acetate Z3-12:Ac	Structural Classification Natural Products Animals Source classification	Others
(Z)-3-Dodecenyl acetate (Z3-12:Ac) is a specific sex pheromone attracting females, isolated from pentane extracts of mature unmated male yellow mealworm beetles .

HY-W747088

(2Z,13Z)-Octadecadienyl acetate	Structural Classification Natural Products Animals Source classification	Others
(2Z,13Z)-Octadecadienyl acetate is a female pheromone that attracts male clearwing moths and disrupts mating, isolated from Japanese persimmon clearwing moths (Synanthedon tenuis (Lepidoptera: Sesiidae)) .

HY-W140227

(Z,Z)-4,7-Decadienol	Structural Classification Natural Products Araceae Source classification Acorus calamus L. Plants	Others
(Z,Z)-4,7-Decadienol is a volatile component of acorus oil essential oil and an uncommon fragrance in orchids .

HY-N12885

(11Z,13E)-Hexadecadienal	Structural Classification Natural Products Animals Source classification	Others
(11Z,13E)-Hexadecadienal is a synthetic isomer of the hexane extract of the unmated female or female pheromone glands that can attract male Amyelois transitella (Walker) (Lepidoptera: Pyralidae) when mixed with (11Z,13Z)-hexadecadien-1-ol, (11Z,13E)-hexadecadien-1-ol, (3Z,6Z,9Z,12Z,15Z)-tricosapentaene (C23 pentaene) .

HY-N12894

(Z,E)-7,11-Hexadecadienyl acetate (7Z,11E)-Gossyplure; (Z7,E11-16:Ac)	Structural Classification Natural Products Animals Source classification	Others
(Z,E)-7,11-Hexadecadienyl acetate ((7Z,11E)-Gossyplure; (Z7,E11-16:Ac)) is a synthetic female sex pheromone effective in attracting Cadra cautella, Pectinophoragossypiella, and Spodoptera exigua .

HY-N10840

Furanogermacra-1(10)Z,4Z-dien-6-one	Structural Classification Commiphora myrrha (Nees) Engl. Terpenoids Sesquiterpenes Source classification Plants Burseraceae	Others
Furanogermacra-1(10)Z,4Z-dien-6-one is a furanosesquiterpenoid that can be found in Commiphora myrrha .

HY-134211

(Z)-2-Octenoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Z-2-Octenoic acid is the Z-isomer of 2-Octenoic acid. trans-2-Octenoic acid is a metabolite of Mucor species.

HY-N11647

Ganoderic acid Z	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Others
Ganoderic acid Z is a ganoderic acid. Ganoderic acid Z, the lanostane triterpenoid, can be isolated from mushrooms of the genus Ganoderma .

HY-N0120

(E/Z)-Polydatin (E/Z)-Piceid	Stilbenes Classification of Application Fields Polygonaceae Source classification Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Others
(E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions .

HY-N12058

(Z)-9-Nonadecene

Structural Classification Natural Products Animals Source classification

Others

(Z)-9-Nonadecene is the anal secretion of a species of thrips .
HY-W108415

Z12-Tetradecenyl acetate

Structural Classification Natural Products Animals Source classification

Others

Z12-Tetradecenyl acetate is a pheromone produced by Ostrinia nubilalis .

HY-N12910

(Z)-9-Hexadecenyl acetate	Structural Classification Natural Products Animals Source classification	Others
(Z)-9-Hexadecenyl acetate is a female sex pheromone isolated from 3-day-old female Mamestra configurata. (Z)-9-Hexadecenyl acetate can induce an electroantennographic response and attract 2-day-old male moths .

HY-W336192

(3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate	Structural Classification Natural Products Animals Source classification	Others
(3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate is a sex pheromone capable of attracting male South American tomato pinworms (Scrobipalpuloides absoluta), which can be isolated from the tomato pest .

HY-W106641

(Z)-7-Dodecen-1-ol	Structural Classification Natural Products Animals Source classification	Others
(Z)-7-Dodecen-1-ol inhibits the effect of the attractant Z-7-dodecen-1-yl acetate .

HY-110066

(Z)-Guggulsterone 2 Publications Verification	Structural Classification Classification of Application Fields Commiphora myrrha (Nees) Engl. Source classification Plants Burseraceae Disease Research Fields Steroids Cancer	Apoptosis VEGFR Akt Angiotensin-converting Enzyme (ACE) SARS-CoV FXR
(Z)-Guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. (Z)-Guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis . (Z)-Guggulsterone is also a potent FXR antagonist. (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection .

HY-W780813

(Z)-3-Decenol

Structural Classification Natural Products Animals Source classification

Others

(Z)-3-Decenol is an insect sex pheromone that specifically attracts male beetles .

HY-N9520

1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone	Cardiovascular Disease Alkaloids Classification of Application Fields Source classification Evodia rutaecarpa (Juss.) Benth. Rutaceae Quinoline Alkaloids Plants Disease Research Fields	Angiotensin Receptor
Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is an antagonist of angiotensin II receptor (IC₅₀=48.2 μM). Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is a quinolone alkaloid from Evodia rutaecarpa .

HY-W780784

(Z,Z)-3,13-Octadecadien-1-ol	Structural Classification Natural Products Animals Source classification	Others
(Z,Z)-3,13-Octadecadien-1-ol is an insect sex pheromone used for trapping redwood resin borers (Synanthedon sequoiae (Edwards)) .

HY-N12936

(Z)-5-Tetradecenyl acetate	Structural Classification Natural Products Animals Source classification	Others
(Z)-5-Tetradecenyl acetate is a sex pheromone for male mottled rustic moths (Euxoa tessellata (Harris)) .

HY-W587916

(Z)-11-Hexadecenoic acid	Structural Classification Natural Products Animals Source classification	Others
(Z)-11-Hexadecenoic acid is a sex pheromone capable of attracting male pine processionary moths (Thaumetopoea pityocampa) .

HY-N12888

4E,6Z,10Z-Hexadecatrien-1-ol	Structural Classification Natural Products Animals Source classification	Others
4E,6Z,10Z-Hexadecatrien-1-ol is the component of insect sex pheromone components of the cocoa pod borer (Conopomorpha cramerella, or Acrocercop cramerella), which plays a role in attracting male moths .

HY-16950A

(E/Z)-4-Hydroxytamoxifen 1 Publications Verification Afimoxifene	Structural Classification Alkaloids Monophenols Classification of Application Fields Other Alkaloids Source classification Phenols Endogenous metabolite Disease Research Fields Cancer	Estrogen Receptor/ERR Endogenous Metabolite
(E/Z)-4-Hydroxytamoxifen (Afimoxifene) is a racemic compound of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen isomers. (E/Z)-4-Hydroxytamoxifen is an estrogen receptor modulator.

HY-W745644

(Z)-7-Hexadecenal	Structural Classification Natural Products Animals Source classification	Others
(Z)-7-Hexadecenal is a sex pheromone that attracts male insects, isolated from female Heliothis virescens moths .

HY-121995

(14Z)-14-Eicosenoic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Others
(14Z)-14-Eicosenoic acid is an unsaturated fatty acid isolated from sponges .

HY-133984

(7Z)-7-Tricosene

Structural Classification Natural Products Animals Source classification

Others

(7Z)-7-Tricosene is a pheromone and can be produced by Aleochar curtula .

HY-W747112

(Z)-10-Hexadecenal	Structural Classification Natural Products Animals Source classification	Others
(Z)-10-Hexadecenal is a fruit-type female pheromone isolated from the abdominal tip extracts of female Dichocrocis punctiferalis .

HY-W742821

(Z)-11-Octadecenal	Structural Classification Natural Products Animals Source classification	Others
(Z)-11-Octadecenal is a female pheromone with diurnal stability, isolated from the pheromone glands of female rice leaffolder moths .

HY-N9530

1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone	Cardiovascular Disease Alkaloids Classification of Application Fields Source classification Evodia rutaecarpa (Juss.) Benth. Rutaceae Metabolic Disease Quinoline Alkaloids Plants Disease Research Fields	Acyltransferase Angiotensin Receptor Bacterial
1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a quinolone alkaloid, is a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, with IC₅₀s of 20.1 μM and 34.1 μM, respectively. 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone shows potent anti-Helicobacter pylori activity with the MIC of 10 μg/mL .

HY-13212

(Z)-2-Decenoic acid cis-2-Decenoic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Cancer	Others
(Z)-2-decenoic acid (cis-2-Decenoic acid) is an unsaturated fatty acid produced by Pseudomonas aeruginosa. (Z)-2-decenoic acid induces a dispersion response in biofilms formed by a range of gram-negative bacteria, including P. aeruginosa, and by gram-positive bacteria. (Z)-2-decenoic acid inhibits biofilm development .

HY-N12884

(11Z,13E)-Hexadecadien-1-ol Z11,E13-16:OH	Structural Classification Natural Products Animals Source classification	Others
(11Z,13E)-Hexadecadien-1-ol (Z11,E13-16:OH) is a insect sex pheromone, which could be secreted by adult females of the grass web moth (Herpetogramma licarsisalis) .

HY-N11031

Z-Antiepilepsirine	Structural Classification Alkaloids Piperidine Alkaloids Piper capense Source classification Piperaceae Plants	Parasite
Z-Antiepilepsirine is an amide alkaloid that can be found in Piper capense L.f. Z-Antiepilepsirine shows antiplasmodial activity with an IC₅₀ value of 27 µM for W2 strain of Plasmodium falciparum .

HY-N12113

9-(Z)-Pentacosene	Structural Classification Natural Products Animals Source classification	Others
9-(Z)-Pentacosene is a olefin that can be isolated from Fannia canicularis. 9-(Z)-Pentacosene has anti-insect activity .

HY-101735

(9Z,11E)-Prodlure (9Z,11E)-Tetradecadien-1-yl acetate; Ferodin SL; Litlure A	Structural Classification Natural Products Microorganisms Classification of Application Fields Animals Source classification Disease Research Fields Endocrinology	Others
(9Z,11E)-Prodlure ((9Z,11E)-Tetradecadien-1-yl acetate) is the main component of the sex pheromone of female Spodoptera littoralis .

HY-133985

7(Z)-Pentacosene	Structural Classification Natural Products Animals Source classification	Others
7(Z)-Pentacosene is an aggregation pheromone of the European earwig (Forficula auricularia). 7(Z)-Pentacosene can be used in the study of insect behavior and neurobiology .

HY-N12880

(10E,12Z)-10,12-Hexadecadien-1-ol Z10,E12-16:OH	Structural Classification Natural Products Animals Source classification	Others
(10E,12Z)-10,12-Hexadecadien-1-ol (Z10,E12-16:OH) is a microlepidopteran attractant isolated from female scent glands .

HY-W016814

(Z)-Aconitic acid 1 Publications Verification cis-Aconitic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(Z)-Aconitic acid (cis-Aconitic acid) is the cis-isomer of Aconitic acid. (Z)-Aconitic acid (cis-Aconitic acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.

HY-N12909

(Z,E)-9,12-Tetradecadienal Z9,E12-14:Ald	Structural Classification Natural Products Animals Source classification	Others
(Z,E)-9,12-Tetradecadienal (Z9,E12-14:Ald) is a female pheromone that can induce an electroantennographic response in male antennae, isolated from the sex pheromone extracts of Plodia interpunctella (lepidoptera: pyralidae) .

HY-N4325

Onjisaponin Z

Triterpenes Terpenoids Source classification Polygalaceae Plants Polygala tenuifolia Willd.

Others

Onjisaponin Z is a natural product isolated from Radix Polygalae.

Species:	Human (17) Virus (1) Mouse (5) Cynomolgus (2) E.coli (6)
Tag:	His (28) SUMO (6) Tag Free (1) Avi (2) Myc (2) GST (1) Fc (3) B2M (1)
Source:	HEK293 (16) Sf9 insect cells (2) E. coli (13)

Cat. No.	Compare	Product Name	Species	Source

HY-P75448

	Cathepsin Z/CTSZ Protein, Mouse (HEK293, His) Cathepsin P; Cathepsin X/Z/P; Cathepsin Z; CTSX; CTSZ	Mouse	HEK293
	The cathepsin Z/CTSZ protein displays multiple carboxyl monopeptidase and carboxyl dipeptidase activities, emphasizing its enzymatic versatility. It is capable of expertly producing kinin-enhancing peptides, which play a vital role in regulating biological processes. Cathepsin Z/CTSZ Protein, Mouse (HEK293, His) is the recombinant mouse-derived Cathepsin Z/CTSZ protein, expressed by HEK293 , with C-His labeled tag. The total length of Cathepsin Z/CTSZ Protein, Mouse (HEK293, His) is 284 a.a., with molecular weight of ~38 kDa.

HY-P71412

	UBE2Z Protein, Human (His) Ubiquitin-Conjugating Enzyme E2 Z; Uba6-Specific E2 Conjugating Enzyme 1; Use1; Ubiquitin Carrier Protein Z; Ubiquitin-Protein Ligase Z; UBE2Z; HOYS7	Human	E. coli
	UBE2Z Protein, a catalyst in ubiquitin conjugation, facilitates the covalent attachment of ubiquitin to target proteins. It serves as a specific substrate for UBA6 and is implicated in the regulation of apoptosis. UBE2Z Protein, Human (His) is the recombinant human-derived UBE2Z protein, expressed by E. coli , with N-6*His labeled tag. The total length of UBE2Z Protein, Human (His) is 246 a.a., with molecular weight of ~32.0 kDa.

HY-P7758

	Cathepsin Z/CTSZ Protein, Human (HEK293, His) rHuCathepsin X, His; Cathepsin Z; Cathepsin P; Cathepsin X; CTSZ	Human	HEK293
	Cathepsin X Protein, Human (HEK293, His) is a lysosomal cysteine protease, found predominantly in cells of monocyte/macrophage lineage.

HY-P7758A

	Cathepsin Z/CTSZ Protein, Human (HEK293, C-His) rHuCathepsin X, His; Cathepsin Z; Cathepsin P; Cathepsin X; CTSZ	Human	HEK293
	Cathepsin Z/CTSZ Protein exhibits dual carboxy-monopeptidase and carboxy-dipeptidase activities, as evidenced by research. Additionally, it displays functional versatility by generating kinin potentiating peptides. Cathepsin Z/CTSZ Protein, Human (HEK293, C-His) is the recombinant human-derived Cathepsin Z/CTSZ protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Cathepsin Z/CTSZ Protein, Human (HEK293, C-His) is 280 a.a., with molecular weight of 37-40 kDa.

HY-P76220

	CD3 zeta/CD247 Protein, Human (His) T-cell surface glycoprotein CD3 zeta chain; CD247; CD3Z; T3Z; TCRZ	Human	E. coli
	CD3 zeta/CD247 is a component of the TCR-CD3 complex and can transmit APC-induced TCR signals to initiate immune responses. CD3D, CD3E, CD3G, and CD3Z contain ITAMs that are phosphorylated by LCK and FYN upon TCR engagement, providing docking sites for ZAP70. CD3 zeta/CD247 Protein, Human (GST) is the recombinant human-derived CD3 zeta/CD247 protein, expressed by E. coli , with N-GST labeled tag. The total length of CD3 zeta/CD247 Protein, Human (GST) is 113 a.a., with molecular weight of 28-43 KDa.

HY-P76699

	VSIG4 Protein, Mouse (HEK293, His-Fc) V-set and immunoglobulin domain-containing protein 4; Protein Z39Ig; Z39IG; CRIg	Mouse	HEK293
	V-set and immunoglobulin domain containing 4 (Vsig4) is a membrane protein belonging to complement receptor of the immunoglobulin superfamily. Vsig4 may be a negative regulator of T-cell responses and interleukin-2 production, Vsig4 also mediates clearance of C3b opsonized pathogens by binding C3b. The expression of VSIG4 is restricted to tissue macrophages where Vsig4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism. VSIG4 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived VSIG4 protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of VSIG4 Protein, Mouse (HEK293, His-Fc) is 187 a.a., with molecular weight of ~60 kDa.

HY-P71423

	VSIG4 Protein, Human (HEK293, Fc) V-set and immunoglobulin domain-containing protein 4; VSIG4; Protein Z39Ig; Z39IG; CRIg	Human	HEK293
	VSIG4 Protein, a phagocytic receptor, robustly inhibits T-cell proliferation and IL2 production, serving as a potent alternative complement pathway convertase inhibitor. VSIG4 Protein, Human (HEK293, Fc) is the recombinant human-derived VSIG4 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of VSIG4 Protein, Human (HEK293, Fc) is 265 a.a., with molecular weight of ~75.0 kDa.

HY-P77042

	KIR3DL3/CD158z Protein, Human (HEK293, His) Killer cell immunoglobulin-like receptor 3DL3; CD158Z; KIR3DL7; KIRC1	Human	HEK293
	KIR3DL3/CD158z, on natural killer cells, potentially inhibits NK cell activity, contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating NK cell functions and maintaining immune homeostasis. KIR3DL3/CD158z Protein, Human (HEK293, His) is the recombinant human-derived KIR3DL3/CD158z protein, expressed by HEK293 , with C-His labeled tag. The total length of KIR3DL3/CD158z Protein, Human (HEK293, His) is 297 a.a., with molecular weight of 40-50 KDa.

HY-P71424

	VSIG4 Protein, Human (264a.a, HEK293, His) V-Set and Immunoglobulin Domain-Containing Protein 4; Protein Z39Ig; VSIG4; CRIg; Z39IG	Human	HEK293
	VSIG4 Protein, a phagocytic receptor, robustly inhibits T-cell proliferation and IL2 production, serving as a potent alternative complement pathway convertase inhibitor. VSIG4 Protein, Human (264a.a, HEK293, His) is the recombinant human-derived VSIG4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of VSIG4 Protein, Human (264a.a, HEK293, His) is 264 a.a., with molecular weight of ~50.0 kDa.

HY-P78475

	KIR3DL3/CD158z Protein, Human (HEK293, His-Avi) CD158Z; KIR2DS2; KIR3DL7; KIR44; KIRC1; KIR3DL3	Human	HEK293
	KIR3DL3/CD158z, on natural killer cells, potentially inhibits NK cell activity, contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating NK cell functions and maintaining immune homeostasis. KIR3DL3/CD158z Protein, Human (HEK293, His-Avi) is the recombinant human-derived KIR3DL3/CD158z protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of KIR3DL3/CD158z Protein, Human (HEK293, His-Avi) is 297 a.a., with molecular weight of 48-52 kDa.

HY-P78167

	KIR3DL3/CD158z Protein, Human (Biotinylated, HEK293, His-Avi) CD158Z; KIR2DS2; KIR3DL7; KIR44; KIRC1; KIR3DL3	Human	HEK293
	KIR3DL3/CD158z, on natural killer cells, potentially inhibits NK cell activity, contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating NK cell functions and maintaining immune homeostasis. KIR3DL3/CD158z Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived KIR3DL3/CD158z protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR3DL3/CD158z Protein, Human (Biotinylated, HEK293, His-Avi) is 297 a.a., with molecular weight of 45-50 kDa.

HY-P700898

	CD20/MS4A1 Protein, Human (HEK293, His) CRIg; Z39IG; VSIG4	Cynomolgus	HEK293
	CD20/MS4A1 protein is a B lymphocyte membrane protein that plays a crucial regulatory role in cellular calcium influx, which is essential for the development, differentiation and activation of B lymphocytes. As part of a store-operated calcium (SOC) channel, it promotes calcium influx upon B cell receptor/BCR activation. CD20/MS4A1 Protein, Human (HEK293, His) is the recombinant cynomolgus-derived CD20/MS4A1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD20/MS4A1 Protein, Human (HEK293, His) is 264 a.a., with molecular weight of 70-80 kDa.

HY-P72516

	IFN-zeta/Limitin Protein, Mouse (HEK293, His) Limitin; IFN-z; BGIF; Ifnz; interferon zeta; Lmtn; IFN-zeta	Mouse	HEK293
	IFN-zeta/Limitin protein is a member of the alpha/beta interferon family. IFN-zeta/Limitin Protein, Mouse (HEK293, His) is the recombinant mouse-derived IFN-zeta/Limitin protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IFN-zeta/Limitin Protein, Mouse (HEK293, His) is 161 a.a., with molecular weight of ~19 kDa.

HY-P71494

	Outer membrane protein X/OmpX Protein, E.coli (Myc, His) ompX; Z1036; ECs0892; Outer membrane protein X	E.coli	E. coli
	Outer membrane protein X/OmpX protein is an important member of the outer membrane OOP (TC 1.B.6) superfamily, specifically belonging to the OmpX family. It plays a vital role in cellular processes and shares common structural and functional features among the OmpX family. Outer membrane protein X/OmpX Protein, E.coli (Myc, His) is the recombinant E. coli-derived Outer membrane protein X/OmpX protein, expressed by E. coli , with N-His, C-Myc labeled tag.

HY-P71493

	Outer membrane protein A/OmpA Protein, E.coli (His-SUMO) ompA; Z1307; ECs1041; Outer membrane protein A; Outer membrane porin A	E.coli	E. coli
	Outer membrane protein A (OmpA) ensures the structural integrity of the bacterial cell wall and cooperates with TolR to stabilize the peptidoglycan layer. As a porin, OmpA controls the permeability of small solutes. Outer membrane protein A/OmpA Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Outer membrane protein A/OmpA protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of Outer membrane protein A/OmpA Protein, E.coli (His-SUMO) is 183 a.a., with molecular weight of ~35.6 kDa.

HY-P71292

	Serpin A10 Protein, Human (HEK293, His) Protein Z-Dependent Protease Inhibitor; PZ-Fependent Protease Inhibitor; PZI; Serpin A10; SERPINA10; ZPI	Human	HEK293
	Serpin A10 protein inhibits coagulation proteases, such as factor Xa, in the presence of PROZ, calcium, and phospholipids. It can also inhibit factor XIa without cofactors. Serpin A10 interacts with PROZ to exert its inhibitory effects on these coagulation factors. Serpin A10 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A10 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A10 Protein, Human (HEK293, His) is 423 a.a., with molecular weight of 55-80 kDa.

HY-P71497

	DNA-binding protein HU-alpha Protein, E.coli (His-SUMO) hupA; Z5576; ECs4923DNA-binding protein HU-alpha; HU-2; NS2	E.coli	E. coli
	DNA-binding protein HU-alpha, a histone-like DNA-binding protein, wraps DNA, offering stabilization and preventing denaturation in challenging conditions. Comprising alpha and beta chains in a heterodimer, it demonstrates versatile DNA binding and protective functions. DNA-binding protein HU-alpha Protein, E.coli (His-SUMO) is the recombinant E. coli-derived DNA-binding protein HU-alpha protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P76639

	Serpin A10 Protein, Mouse (HEK293, His) Protein Z-Dependent Protease Inhibitor; PZ-Fependent Protease Inhibitor; PZI; Serpin A10; SERPINA10; ZPI	Mouse	HEK293
	Serpin A10 Protein, an inhibitor, regulates by inhibiting the activity of coagulation protease factor Xa in the presence of PROZ, calcium, and phospholipids. It also shows inhibitory effects on factor XIa even without cofactors, highlighting its versatility in modulating key components of the coagulation cascade. Serpin A10 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A10 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A10 Protein, Mouse (HEK293, His) is 427 a.a., with molecular weight of 60-80 kDa.

HY-P71436

	ZBP1 Protein, Human (His) Z-DNA-Binding Protein 1; Tumor Stroma and Activated Macrophage Protein DLM; ZBP1; C20orf183; DLM1	Human	E. coli
	ZBP1 is an important innate sensor that defends against viruses by recognizing Z-RNA structures and inducing PANoptosis. It binds Z-RNA through TNF-α family members and stimulates RIPK3 and MLKL to activate necroptosis. ZBP1 Protein, Human (His) is the recombinant human-derived ZBP1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of ZBP1 Protein, Human (His) is 149 a.a., with molecular weight of 16-23 kDa.

HY-P73649

	SHP-1 Protein, Mouse (sf9, His-GST) Tyrosine-protein phosphatase non-receptor type 6; 70Z-SHP; PTP-1C; SHP-1; Ptpn6	Mouse	Sf9 insect cells
	SHP-1 Protein modulates signaling from tyrosine-phosphorylated cell surface receptors, including KIT and EGFR. It enhances the inhibition of mast cell activation via the Lilrb4a receptor. The SH2 regions interact with cellular components to regulate its phosphatase activity. In collaboration with MTUS1, it induces UBE2V2 expression upon angiotensin II stimulation. SHP-1 plays a crucial role in hematopoiesis. SHP-1 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived SHP-1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of SHP-1 Protein, Mouse (sf9, His-GST) is 391 a.a., with molecular weight of ~63 kDa.

HY-P71501

	PPIase A Protein, E.coli (His-SUMO) ppiA; Z4724; ECs4214; Peptidyl-prolyl cis-trans isomerase A; PPIase A; EC 5.2.1.8; Cyclophilin A; Rotamase A	E.coli	E. coli
	The PPIase A protein plays a central role in complex protein folding, utilizing its peptidyl-prolyl cis-trans isomerase (PPIase) activity to accelerate dynamic conformational changes that are critical for proper protein maturation. PPIase A specifically catalyzes the cis-trans isomerization of proline imide peptide bonds, effectively promoting protein folding. PPIase A Protein, E.coli (His-SUMO) is the recombinant E. coli-derived PPIase A protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P71610

	Outer membrane porin C/OmpC Protein, E.coli (Myc, His-SUMO) ompC; Z3473; ECs3104; Outer membrane porin C; Outer membrane protein 1B; Outer membrane protein C; Porin OmpC	E.coli	E. coli
	Outer membrane porin C/OmpC Protein facilitates substance transport across the bacterial outer membrane, forming homotrimeric pores for passive diffusion of small molecules, crucial for maintaining cell envelope permeability. Outer membrane porin C/OmpC Protein, E.coli (Myc, His-SUMO) is the recombinant E. coli-derived Outer membrane porin C/OmpC protein, expressed by E. coli , with N-His, C-Myc, N-SUMO labeled tag.

HY-P70170

	Fetuin A/AHSG Protein, Human (HEK293, His) rHuAlpha-2-HS-glycoprotein/AHSG, His; Alpha-2-HS-Glycoprotein; Alpha-2-Z-Globulin; Ba-Alpha-2-Glycoprotein; Fetuin-A; AHSG; FETUA	Human	HEK293
	Fetuin A (or AHSG protein) plays multiple roles in cellular processes, promotes endocytosis and displays opsonic properties. It regulates the mineral phase of bone, affects bone homeostasis, and has significant affinity for calcium and barium ions. Fetuin A/AHSG Protein, Human (HEK293, His) is the recombinant human-derived Fetuin A/AHSG protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Fetuin A/AHSG Protein, Human (HEK293, His) is 349 a.a., with molecular weight of ~60.0 kDa.

HY-P71474

	Protease 7/OmpT Protein, E.coli (His-SUMO) ompT; Z1931; ECs1663; Protease 7; EC 3.4.23.49; Omptin; Outer membrane protein 3B; Protease A; Protease VII	E.coli	E. coli
	Protease 7, or OmpT, displays unique proteolytic capabilities, cleaving diverse substrates like T7 RNA polymerase, ferric enterobactin receptor protein (FEP), and protamine. With specificity for paired basic residues, it selectively targets substrates with such motifs, highlighting its pivotal role in diverse biological processes and protein regulation. Protease 7/OmpT Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Protease 7/OmpT protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P75031

	HA/Hemagglutinin Protein, H5N1 (Q207Z6, sf9, His) Influenza A H5N1 (A/turkey/Turkey/1/2005) Hemagglutinin / HA Protein (sf9, His)	Virus	Sf9 insect cells
	The HA/Hemagglutinin Protein attaches to sialic acid receptors, initiating virus internalization via clathrin-dependent or -independent pathways. It crucially determines host range and virulence, mediating fusion between the endocytosed virus particle's membrane and the endosomal membrane as a Class I viral fusion protein. In the low pH endosome environment, HA2 undergoes an irreversible conformational change, releasing the fusion hydrophobic peptide. Multiple HA trimers are essential for a competent fusion pore. Its roles in receptor binding, internalization, fusion, and membrane penetration shape viral characteristics. HA/Hemagglutinin Protein, H5N1 (Q207Z6, sf9, His) is the recombinant Virus-derived HA/Hemagglutinin protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of HA/Hemagglutinin Protein, H5N1 (Q207Z6, sf9, His) is 531 a.a., with molecular weight of ~60.1 kDa.

HY-P77966

	IL-33 Protein, Cynomolgus (HEK293, His) C9orf26 Z; DVS27; IL1F11; NF-HEV; NFEHEV; IL33; DV27; C9ORF26; RP11-575C20.2	Cynomolgus	HEK293
	IL-33 Protein, part of the IL-1 family, is a divergent cytokine pivotal in immune responses and inflammation. Operating through its receptor ST2, IL-33 promotes activation and recruitment of immune cells like Th2 cells, mast cells, and eosinophils to inflammation sites. Produced by epithelial and endothelial cells, IL-33 induces pro-inflammatory cytokines and chemokines. Implicated in asthma, allergic diseases, and autoimmune disorders, IL-33 emerges as a therapeutic target for immune response modulation. IL-33 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-33 protein, expressed by HEK293, with N-His labeled tag. The total length of IL-33 Protein, Cynomolgus (HEK293, His) is 162 a.a., with molecular weight of 25-30 kDa.

HY-P72116

	CAPZA2 Protein, Human (His-SUMO) CAPPA2 ; Capping protein actin filament; muscle Z line; alpha 2 ; CapZ alpha 2; CapZ alpha-2; CAPZ; CAPZA2; CAZA2_HUMAN; F actin capping protein alpha 2 subunit; F actin capping protein subunit alpha 2; F-actin-capping protein subunit alpha-2	Human	E. coli
	The CAPZA2 protein is a member of the F-actin capping protein family and binds to the barbed ends of actin filaments, preventing subunit exchange without severing the filaments. CAPZA2 Protein, Human (His-SUMO) is the recombinant human-derived CAPZA2 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of CAPZA2 Protein, Human (His-SUMO) is 285 a.a., with molecular weight of ~48.8 kDa.

HY-P70455

	IL-37 Protein, Human 1 Publications Verification Interleukin-37; FIL1 Zeta; IL-1X; Interleukin-1 Family Member 7; IL-1F7; Interleukin-1 Homolog 4; IL-1H; IL-1H4; Interleukin-1 Zeta; IL-1 Zeta; Interleukin-1-Related Protein; IL-1RP1; Interleukin-23; IL-37; IL37; FIL1Z; IL1F7; IL1H4; IL1RP1	Human	E. coli
	IL-37 protein is an important immunoregulatory cytokine that suppresses innate inflammation and immune responses and reduces excessive inflammation. It signals intracellularly through nuclear translocation of SMAD3 and extracellularly through binding to its receptors, consisting of IL18R1 and IL18RAP. IL-37 Protein, Human is the recombinant human-derived IL-37 protein, expressed by E. coli , with tag free. The total length of IL-37 Protein, Human is 166 a.a., with molecular weight of ~18-20 kDa.

HY-P700128AF

	Animal-Free IL-37 Protein, Human (His) Interleukin-37; FIL1 Zeta; IL-1X; Interleukin-1 Family Member 7; IL-1F7; Interleukin-1 Homolog 4; IL-1H; IL-1H4; Interleukin-1 Zeta; IL-1 Zeta; Interleukin-1-Related Protein; IL-1RP1; Interleukin-23; IL-37; IL37; FIL1Z; IL1F7; IL1H4; IL1RP1	Human	E. coli
	IL-37 protein is an important immunoregulatory cytokine that suppresses innate inflammation and immune responses and reduces excessive inflammation. It signals intracellularly through nuclear translocation of SMAD3 and extracellularly through binding to its receptors, consisting of IL18R1 and IL18RAP. Animal-Free IL-37 Protein, Human (His) is the recombinant human-derived animal-FreeIL-37 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-37 Protein, Human (His) is 166 a.a., with molecular weight of ~19.49 kDa.

HY-P71954

	FGFR-3 Protein, Human (HEK293, hFc) ACH; CD 333; CD333; CD333 antigen; CEK 2; CEK2; FGFR 3; FGFR-3; FGFR3; FGFR3_HUMAN; Fibroblast growth factor receptor 3 achondroplasia thanatophoric dwarfism; ; Fibroblast growth factor receptor 3; Heparin binding growth factor receptor; HSFGFR3EX; Hydroxyaryl protein kinase; JTK 4; JTK4; MFR 3; SAM 3; Tyrosine kinase JTK 4; Tyrosine kinase JTK4; Z FGFR 3	Human	HEK293
	The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 Protein, Human (HEK293, hFc) is the recombinant human-derived FGFR-3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FGFR-3 Protein, Human (HEK293, hFc) is 353 a.a., with molecular weight of ~90 kDa.

HY-P72196

	FGFR-3 Protein, Human (His-B2M) ACH; CD 333; CD333; CD333 antigen; CEK 2; CEK2; FGFR 3; FGFR-3; FGFR3; FGFR3_HUMAN; Fibroblast growth factor receptor 3 achondroplasia thanatophoric dwarfism; ; Fibroblast growth factor receptor 3; Heparin binding growth factor receptor; HSFGFR3EX; Hydroxyaryl protein kinase; JTK 4; JTK4; MFR 3; SAM 3; Tyrosine kinase JTK 4; Tyrosine kinase JTK4; Z FGFR 3	Human	E. coli
	The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 Protein, Human (His-B2M) is the recombinant human-derived FGFR-3 protein, expressed by E. coli , with N-6*His, N-B2M labeled tag. The total length of FGFR-3 Protein, Human (His-B2M) is 410 a.a., with molecular weight of ~59.4 kDa.

Cat. No.	Product Name	Chemical Structure

HY-139507S

Z,Z-Dienestrol-d6

Z,Z-Dienestrol-d₆ is the deuterium labeled Z,Z-Dienestrol[1].

HY-100646AS

(Z)-10-Hydroxynortriptyline-d3
(Z)-10-Hydroxynortriptyline-d₃ is the deuterium labeled (Z)-10-Hydroxynortriptyline (HY-100646A). (Z)-10-Hydroxynortriptyline is a metabolite of Nortriptyline (HY-118620). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1][2].

HY-132477S

(Z)-4-Hydroxy Tamoxifen-d5

(Z)-4-Hydroxy Tamoxifen-d₅ is the deuterium labeled (Z)-4-Hydroxy Tamoxifen[1].
HY-145003S

4(Z),7(Z)-Decadienoic acid-d5

4(Z),7(Z)-Decadienoic acid-d₅ is the deuterium labeled 4(Z),7(Z)-Decadienoic acid[1].
HY-139089S

(Z)-Entacapone-d10

(Z)-Entacapone-d₁₀ is the deuterium labeled (Z)-Entacapone[1].
HY-N0117AS

(Z)-Indirubin-d4

(Z)-Indirubin-d₄ is the deuterium labeled (Z)-Indirubin[1].
HY-N0117AS1

(Z)-Indirubin-d8

(Z)-Indirubin-d₈ is the deuterium labeled (Z)-Indirubin[1].
HY-N0401AS

(Z)-Ligustilide-d7

(Z)-Ligustilide-d₇ is the deuterium-labeled (Z)-Ligustilide (HY-N0401A) .
HY-B0274CS

(E/Z)-Chlorprothixene-d6 hydrochloride

(E/Z)-Chlorprothixene-d₆ hydrochloride is the deuterium labeled (E/Z)-Chlorprothixene hydrochloride .
HY-10448S

(E/Z)-Capsaicin-d3

(E/Z)-Capsaicin-d₃ is the deuterium labeled (E/Z)-Capsaicin[1].
HY-B1808S

(E/Z)-Triprolidine-d8 hydrochloride

(E/Z)-Triprolidine-d₈ (hydrochloride) is the deuterium labeled (E/Z)-Triprolidine hydrochloride[1].
HY-W007750S

H-Lys(Z)-OH-d3

H-Lys(Z)-OH-d₃ is the deuterium labeled H-Lys(Z)-OH.
HY-W587719S

(E/Z)-Glycidyl Linoleate-d5

(E/Z)-Glycidyl Linoleate-d₅ is the deuterium labled (E/Z)-Glycidyl Linoleate.
HY-143676S

(1E,4Z,6E)-Curcumin-d6

(1E,4Z,6E)-Curcumin-d₆ is the deuterium labeled (1E,4Z,6E)-Curcumin[1].
HY-B0426AS1

(Z)-Olopatadine-d3 hydrochloride

(Z)-Olopatadine-d₃ (hydrochloride) is deuterium labeled Olopatadine (hydrochloride).
HY-146919S

4E,14Z-Sphingadiene-d7

4E,14Z-Sphingadiene-d₇ is deuterium labeled 4E,14Z-Sphingadiene.
HY-156260S

Gamma-6Z-Dodecenolactone-d2

Gamma-6Z-Dodecenolactone-d₂ is deuterated labeled Gamma-6Z-Dodecenolactone.
HY-150533S

(E/Z)-Mycophenolic Acid-13C,d3

(E/Z)-Mycophenolic Acid- ¹³C,d₃ is the deuterium and ¹³C labeled (E/Z)-Mycophenolic Acid[1].
HY-W013326S

Bisphenol Z-d6

Bisphenol Z-d₆is the deuterium labeled4,4'-(Cyclohexane-1,1-diyl)diphenol(HY-W013326) .

HY-W016814S

(Z)-Aconitic acid-13C6
(Z)-Aconitic acid- ¹³C₆ is the ¹³C-labeled (Z)-Aconitic acid (HY-W016814). (Z)-Aconitic acid- ¹³C₆ (cis-Aconitic acid) is the cis-isomer of Aconitic acid. (Z)-Aconitic acid- ¹³C₆ (cis-Aconitic acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.

HY-115705S

1,2,3-Tri-10(Z)-Heptadecenoyl Glycerol-d5

1,2,3-Tri-10(Z)-Heptadecenoyl Glycerol-d₅ is the deuterium labeled 1,2,3-Tri-10(Z)-Heptadecenoyl Glycerol[1].
HY-156326S1

(3E,5Z)-Octadien-2-one-13C2

(3E,5Z)-Octadien-2-one- ¹³C₂ is ¹³C labeled (3E,5Z)-Octadien-2-one.
HY-W392083S1

(1,3E,5Z)-Undeca-1,3,5-triene-d5

(1,3E,5Z)-Undeca-1,3,5-triene-d₅ is deuterated labeled 2-Methyl-3-(methyldisulfanyl)furan.
HY-157075S

(Z)-Rilpivirine-d4

(Z)-Rilpivirine-d₄ (R278474-d₄; TMC278-d₄; DB08864-d₄) is deuterium-labeled (Z)-Rilpivirine .

HY-146874S

D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-hexadecen-1-yl]oxy]propyl hydrogen phosphate], ammonium salt (1:1)
D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-hexadecen-1-yl]oxy]propyl hydrogen phosphate]-d₅, ammonium salt (1:1) is an isotopically labeled compound.

HY-146873S

D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-tetradecen-1-yl]oxy]propyl hydrogen phosphate], ammonium salt (1:1)
D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-tetradecen-1-yl]oxy]propyl hydrogen phosphate]-d₅, ammonium salt (1:1) is an isotopically labeled compound.

HY-B0005S1

Toremifene-d6 hydrochloride
Toremifene-d6 (Z-Toremifene-d6) hydrochloride is deuterium labeled Toremifene. Toremifene is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC₅₀ of 0.07 µM and 2.6 µM, respectively .

HY-B0005AS

Toremifene-d6
Toremifene-d₆ is deuterium labeled Toremifene. Toremifene (Z-Toremifene) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 µM and 2.6 µM, respectively[1][2].

HY-16950BS

(E)-4-Hydroxytamoxifen-d5
(E)-4-Hydroxytamoxifen-d5 ((E)-Afimoxifene-d5) is the deuterium labeled (E)-4-Hydroxytamoxifen. (E)-4-Hydroxytamoxifen ((E)-Afimoxifene), the less active isomer of (Z)-4-hydroxytamoxifen, is an estrogen receptor modulator.

HY-B0448S

Phenytoin-d10
Phenytoin-d₁₀ is the deuterium labeled Phenytoin. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[1][2].

HY-109506S1

DPPC-d9
DPPC-d₉ is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].

HY-109506S

DPPC-d62
DPPC-d₆₂ is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].

HY-109506S3

DPPC-d9-1
DPPC-d₉-1 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].

HY-16561S2

(E/Z)-Resveratrol-13C6

Resveratrol-(4-Hydroxyphenyl)- ¹³CN₆ is the ¹³C labeled Resveratrol-(4-Hydroxyphenyl)[1].

HY-B0448S1

Phenytoin-15n2,13c
Phenytoin- ¹⁵N₂, ¹³C is the ¹³C and ¹⁵N labeled Phenytoin[1]. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[2][3].

HY-15306S

Eltrombopag-13C4

1 Publications Verification

Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-W013053S

Dibenz[a,h]anthracene-d14

Dibenz[a,h]anthracene-d₁₄ is the deuterium Dibenz[a,h]anthracene.

HY-B1002S

Oxolinic acid-d5
Oxolinic acid-d₅ is the deuterium labeled Oxolinic acid. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice[1][2][3].

HY-113354S

Anserine-d4

Anserine-d₄ is the deuterium labeled Anserine. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].

HY-N1428S3

Citric acid-13C3
Citric acid- ¹³C₃ is the ¹³C labeled Citric acid[1]. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[2][3][4].

HY-B0732S

Itopride-d6 hydrochloride
Itopride-d₆ (hydrochloride) is deuterium labeled Itopride (hydrochloride). Itopride hydrochloride (HSR803), a gastroprokinetic Benzamide (HY-Z0283) derivative, is an inhibitor of acetylcholinesterase (AChE) and dopamine D2 receptor[1][2].

HY-120546S

Ulixacaltamide-d9 hydrochloride

Ulixacaltamide-d₉ (hydrochloride) salt is the deuterium labeled Ulixacaltamide hydrochloride[1].

HY-124412S

Paynantheine-d3
Paynantheine-d₃ is a deuterium labeled Paynantheine. Paynantheine is an alkaloid that can be isolated from Mitragyna speciosa. Paynantheine can decrease alcohol intake in mice .

HY-135502S

Speciogynine-d3
Speciogynine-d₃ is a deuterium labeled Speciogynine. Speciogynine is an alkaloid that can be isolated from Mitragyna speciosa. Speciogynine can decrease alcohol intake in mice .

HY-163164S

18:1-17:1-18:1 TG-d5

18:1-17:1-18:1 TG-d5, 1,3-dioleoyl-2-heptadec-10Z-enoyl-glycerol-d5, is a deuterated substance .

HY-D0195S

Acesulfame-d4 potassium
Acesulfame-d₄ potassiumis the deuterium labeledAcesulfame (potassium)(HY-D0195) . Acesulfame potassium is an artificial sweetener. Acesulfame potassium (long-term) affects cognitive functions, potentially via altering neuro-metabolic functions in mice .

HY-14393S

Emodin-d4

Emodin-d₄ is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3].

HY-B0005S

Toremifene-d6 citrate
Toremifene-d₆ (citrate) is the deuterium labeled Toremifene citrate. Toremifene citrate (Z-Toremifene citrate) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 µM and 2.6 µM, respectively[1][2].

HY-B0534S1

Moclobemide-d4
Moclobemide-d₄ is deuterium labeled Moclobemide. Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A[1].Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.

HY-145119S

Mindeudesivir
GS-621763-d₁ is the deuterium labeled GS-621763 (HY-145119) . GS-621763, an orally bioavailable proagent of GS-441524, shows antiviral activity against SARS-CoV-2 pathogenesis in mice .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82007

	RPS19 Antibody (YA1752) DBA; DBA1; Ribosomal protein S19; rps19; S19	WB, IHC-P, IP	Human, Mouse, Rat
	RPS19 Antibody (YA1752) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1752), targeting RPS19, with a predicted molecular weight of 16 kDa (observed band size: 16 kDa). RPS19 Antibody (YA1752) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

HY-P83435

	Caspase 14 Antibody (YA3180) CASP14; Caspase-14; Caspase 14; mice; CASP-14	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	Caspase 14 Antibody (YA3180) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3180), targeting Caspase 14, with a predicted molecular weight of 28 kDa (observed band size: 28 kDa). Caspase 14 Antibody (YA3180) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P80162

	Histone H2A.Z Antibody	WB, IHC-P, ICC/IF	Human, Mouse
	Histone H2A.Z Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 14 kDa, targeting to Histone H2A.Z. It can be used for WB,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse.

HY-P82637

	Cathepsin Z Antibody (YA2382) CTSX	WB, IHC-P	Human
	Cathepsin Z Antibody (YA2382) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2382), targeting Cathepsin Z, with a predicted molecular weight of 34 kDa (observed band size: 34 kDa). Cathepsin Z Antibody (YA2382) can be used for WB, IHC-P experiment in human background.

HY-P82680

	Phospho-CD3 zeta (Tyr142) Antibody (YA2425) CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD antigen CD247	WB, IP	Human
	Phospho-CD3 zeta (Tyr142) Antibody (YA2425) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2425), targeting Phospho-CD3 zeta (Tyr142), with a predicted molecular weight of 19 kDa (observed band size: 19 kDa). Phospho-CD3 zeta (Tyr142) Antibody (YA2425) can be used for WB, IP experiment in human background.

HY-P80913

	Thioredoxin Reductase 2 Antibody (YA661) mitochondrial; selenoprotein Z; SELZ; Thioredoxin reductase 2; Thioredoxin reductase 2 mitochondrial; thioredoxin reductase 3; thioredoxin reductase beta; Thioredoxin reductase TR3; TR 3; TR; TR beta; TR-beta; TRXR 2; TRXR2; TRXR2_HUMAN; TXNRD 2; Txnrd2.	WB	Human
	Thioredoxin Reductase 2 Antibody (YA661) is a non-conjugated and Mouse origined monoclonal antibody about 57 kDa, targeting to Thioredoxin Reductase 2 (3F2). It can be used for WB assays with tag free, in the background of Human.

Cat. No.	Product Name		Classification

HY-151761

H-L-Lys(4-N3-Z)-OH hydrochloride		Azide Labeling and Fluorescence Imaging
H-L-Lys(4-N3-Z)-OH hydrochloride is a click chemistry reagent containing an azide group. H-L-Lys(4-N3-Z)-OH hydrochloride contains a lysine-modified azide moiety and as a bioorthogonal ligation handle. H-L-Lys(4-N3-Z)-OH hydrochloride is an infrared probe and a photo-affinity reagent .

HY-151668

Z-L-Aha-OH

Azide

Z-L-Aha-OH is a click chemistry reagent containing azide group .
HY-151732

Z-D-Dbu(N3)-OH

Azide

Z-D-Dbu(N3)-OH is a click chemistry reagent containing an azide group. Z-D-Dbu(N3)-OH can be used for the research of various biochemical .
HY-151668A

Z-L-Aha-OH (DCHA)

Azide

Z-L-Aha-OH (DCHA) is a click chemistry reagent containing azide group .

HY-151737

Z-L-Dbu(N3)-OH		Azide
Z-L-Dbu(N3)-OH is a click chemistry reagent containing an Azide . Z-L-Dbu(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-151679

Fmoc-L-Lys(4-N3-Z)-OH		Azide
Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition . Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-151849

Z-L-Dap(N3)-OH		Azide
Z-L-Dap(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .

HY-108039

Bezisterim HE 3286; NE-3107		Alkynes
Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis . Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-158701

KRAS G12D inhibitor 23		Alkynes
KRAS G12D inhibitor 23 (compound 46-3) is a potent inhibitor of KRAS G12D, with the IC₅₀ of 0.007 μM. KRAS G12D inhibitor 23 plays an important role in cancer research .

HY-120171

DH-376		Alkynes
DH-376 is a potent diacylglycerol lipase inhibitor with pIC₅₀ values of 8.6 and 8.9 for ABHD6 and DAGLα, respectively. DH-376 prevents fasting-induced refeeding of mice . DH-376 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W001538

S-Propargylcysteine SPRC		Alkynes
S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H₂S-releasing compound. S-Propargylcysteine reduces Ca ²⁺ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties .

HY-16361A

Omigapil maleate CGP3466B; CGP3446 maleate; TCH346 maleate		Alkynes
Omigapil maleate, an orally bioavailable GAPDH nitrosylation inhibitor, abrogates Aβ_1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease . Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD) . Omigapil (maleate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-100433

PACMA 31		Alkynes
PACMA 31 is an irreversible, orally active protein disulfide isomerase (PDI) inhibitor with an IC₅₀ of 10 μM. PACMA 31 forms a covalent bond with the active site cysteines of PDI. PACMA 31 shows tumor targeting ability and significantly suppresses ovarian tumor growth without causing toxicity to normal tissues . PACMA 31 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151852

9AzNue5Ac		Labeling and Fluorescence Imaging Azide
9AzNue5Ac, 9-azido-9-deoxy-N-acetylneuraminic acid, is a click chemistry reagent and a Neu5Ac analogue with the substitution of 9-hydroxyl group with an azide. 9AzNue5Ac could be metabolized and incorporated into sialoglycans in living cells and mice. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .

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