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RWJ 800025

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-19522

    MBX-8025; RWJ-800025

    PPAR Metabolic Disease
    Seladelpar (MBX-8025) is an orally active, potent (50% effect concentration EC50 2 nM), and specific PPAR-δ agonist .
    Seladelpar
  • HY-19522A

    MBX-8025 sodium salt; RWJ-800025 sodium salt

    PPAR Metabolic Disease
    Seladelpar sodium salt (MBX-8025) is an orally active, potent and specific PPARδ agonist with an EC50 of 2 nM, showing more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively.
    Seladelpar sodium salt
  • HY-19522C

    MBX-8025 Lysine dihydrate; RWJ-800025 Lysine dihydrate

    PPAR Metabolic Disease
    Seladelpar Lysine dihydrate (MBX-8025 Lysine dihydrate; RWJ-800025 Lysine dihydrate) is the Lysine dihydrate salt form of Seladelpar (HY-19522). Seladelpar Lysine dihydrate is an orally active agonist for potent PPAR-δ, with EC50 of 2 nM. Seladelpar Lysine dihydrate normalizes hyperglycemia, hyperinsulinemia, glucose, serum lipids and cholesterol levels, ameliorates the nonalcoholic steatohepatitis in mouse model .
    Seladelpar Lysine dihydrate

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