2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. Seladelpar Lysine dihydrate

Seladelpar Lysine dihydrate  (Synonyms: MBX-8025 Lysine dihydrate; RWJ-800025 Lysine dihydrate)

Cat. No.: HY-19522C
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Seladelpar Lysine dihydrate (MBX-8025 Lysine dihydrate; RWJ-800025 Lysine dihydrate) is the Lysine dihydrate salt form of Seladelpar (HY-19522). Seladelpar Lysine dihydrate is an orally active agonist for potent PPAR-δ, with EC50 of 2 nM. Seladelpar Lysine dihydrate normalizes hyperglycemia, hyperinsulinemia, glucose, serum lipids and cholesterol levels, ameliorates the nonalcoholic steatohepatitis in mouse model.

For research use only. We do not sell to patients.

Seladelpar Lysine dihydrate Chemical Structure

Seladelpar Lysine dihydrate Chemical Structure

CAS No. : 928821-40-3

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Seladelpar Lysine dihydrate Related Antibodies

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Description

Seladelpar Lysine dihydrate (MBX-8025 Lysine dihydrate; RWJ-800025 Lysine dihydrate) is the Lysine dihydrate salt form of Seladelpar (HY-19522). Seladelpar Lysine dihydrate is an orally active agonist for potent PPAR-δ, with EC50 of 2 nM. Seladelpar Lysine dihydrate normalizes hyperglycemia, hyperinsulinemia, glucose, serum lipids and cholesterol levels, ameliorates the nonalcoholic steatohepatitis in mouse model[1][2].

IC50 & Target

PPARδ

2 nM (EC50)

Molecular Weight

626.68

Formula

C27H41F3N2O9S
CAS No.
SMILES

N[C@@H](CCCCN)C(O)=O.O=C(O)COC1=CC=C(SC[C@H](OCC)COC2=CC=C(C(F)(F)F)C=C2)C=C1C.O.O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Seladelpar Lysine dihydrate Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Seladelpar Lysine dihydrate928821-40-3MBX-8025 Lysine dihydrateRWJ-800025 Lysine dihydratePPARPeroxisome proliferator-activated receptorsinsulin resistancediabetesatherogenic dyslipidemiaonalcoholic steatohepatitisNASHInhibitorinhibitorinhibit

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