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Pathways Recommended: PROTAC
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PROTAC EGFR degrader-11

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-161633
    PROTAC EGFR degrader 11

    		PROTACs EGFR FAK Cancer
    PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC50 <100 nM. PROTAC EGFR degrader 11 binds CRBN-DDB1 with a Ki of 36 nM. PROTAC EGFR degrader 11 degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM.
    <em>PROTAC</em> <em>EGFR</em> <em>degrader 11</em>

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