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Results for "

Ca 2 sensitive

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

4

Fluorescent Dye

1

Peptides

1

Recombinant Proteins

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1024
    Coelenterazine h
    2 Publications Verification

    2-Deoxycoelenterazine; CLZN-h

    		 Calcium Channel Biochemical Assay Reagents Neurological Disease
    Coelenterazine h (2-Deoxycoelenterazine), a coelenterazine derivative, is a luminescent substrate for RLuc8. Coelenterazine h is more sensitive to Ca 2+, thus providing a valuable tool for measuring small changes in Ca 2+ concentrations .
    Coelenterazine h
  • HY-D1024A
    Coelenterazine h hydrochloride
    2 Publications Verification

    2-Deoxycoelenterazine hydrochloride; CLZN-h hydrochloride

    		 Biochemical Assay Reagents Calcium Channel Neurological Disease
    Coelenterazine h (2-Deoxycoelenterazine) hydrochloride, a coelenterazine derivative, is a luminescent substrate for RLuc8. Coelenterazine h hydrochloride is more sensitive to Ca 2+, thus providing a valuable tool for measuring small changes in Ca 2+ concentrations .
    Coelenterazine h hydrochloride
  • HY-103474
    Bicuculline methiodide

    (+)-Bicuculline methiodide; d-Bicuculline methiodide

    		 GABA Receptor Neurological Disease
    Bicuculline methiodide is a potent GABA(A) receptors blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca 2+ -activated K + channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca 2+ -activated K + current .
    Bicuculline methiodide
  • HY-104056
    Fura Red

    		Fluorescent Dye Others
    Fura Red is a Ca 2+-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca 2+] .
    Fura Red
  • HY-D1631
    Calcium Green-5N AM

    		Fluorescent Dye Neurological Disease
    Calcium Green-5N AM is a novel Ca 2+-sensitive fluorescent probe. Calcium Green-5N AM shows enhancement in fluorescence intensity on binding Ca 2+, and can monitor free Ca 2+ in neurons .
    Calcium Green-5N AM
  • HY-D1501
    Fura PE-3 potassium

    		Fluorescent Dye Others
    Fura PE-3 potassium is a Ca 2+sensitive fluorophore. Fura PE-3 potassium loads in IPA (intrapulmonary arteries) and MA (mesenteric resistance arteries) for the research of vasoconstriction .
    Fura PE-3 potassium
  • HY-101360
    1-EBIO

    1-Ethyl-2-benzimidazolinone

    		 Potassium Channel Neurological Disease
    1-EBIO is an activator of Ca 2+ sensitive K + channels. 1-EBIO is used to study the role of K + channels in diverse physiological functions .
    1-EBIO
  • HY-147383
    NS-8

    		Potassium Channel Endocrinology
    NS-8, a pyrrole derivative, activates the Ca 2+-sensitive k +-channel. NS-8 can suppress the micturition reflex by decreasing afferent pelvic nerve activity. NS-8 can be used in the research of urinary frequency and incontinence .
    NS-8
  • HY-P5799
    ω-Conotoxin MVIID

    SNX-238

    		 Calcium Channel Neurological Disease
    ω-Conotoxin MVIID (SNX-238) is a Conus peptide that blocks an ω-Conotoxin-GVIA-sensitive, high-threshold Ca 2+ current in fish retinal ganglion cells .
    ω-Conotoxin MVIID
  • HY-124171
    Zinquin ethyl ester

    		Fluorescent Dye Others
    Zinquin ethyl ester is a fluorescent derivative of Zinquin and is a fluorescent probe of cytosolic zinc. Zinquin ethyl ester is able to penetrate cell membranes and is lipophilic and zinc-sensitive. Zinquin ethyl ester can combine with Zn 2+ in the presence of Ca 2+ and Mg 2+ to produce blue fluorescence .
    Zinquin ethyl ester
  • HY-B0246
    Carbamazepine
    Maximum Cited Publications
    10 Publications Verification

    CBZ; NSC 169864

    		 Sodium Channel Autophagy Mitophagy Potassium Channel Calcium Channel HDAC Neurological Disease Cancer
    Carbamazepine is an orally active pressure-sensitive sodium ion channel blocker with an IC50 of 131 μM. Carbamazepine blocks voltage gated Na +, Ca 2+, and K + channels, and is also a HDAC inhibitor (IC50: 2 μM). Carbamazepine is an anticonvulsant and can be used for research of epilepsy and neuropathic pain .
    Carbamazepine
  • HY-135746
    OR-1896
    1 Publications Verification

    		 Potassium Channel Phosphodiesterase (PDE) Drug Metabolite Apoptosis Cardiovascular Disease
    OR-1896 is an active long-lived metabolite of Levosimendan. OR-1896 is a highly selective phosphodiesterase (PDE) III isoform inhibitor and a powerful vasodilator. OR-1896 can open ATP-sensitive K + channels and has Ca 2+-sensitizing effect. OR-1896 mitigates cardiomyocyte apoptosis, cardiac remodeling and myocardial inflammation .
    OR-1896
  • HY-B0246R
    Carbamazepine (Standard)

    		Sodium Channel Autophagy Mitophagy Potassium Channel Calcium Channel HDAC Neurological Disease Cancer
    Carbamazepine (Standard) is the analytical standard of Carbamazepine. This product is intended for research and analytical applications. Carbamazepine is an orally active pressure-sensitive sodium ion channel blocker with an IC50 of 131 μM. Carbamazepine blocks voltage gated Na +, Ca 2+, and K + channels, and is also a HDAC inhibitor (IC50: 2 μM). Carbamazepine is an anticonvulsant and can be used for research of epilepsy and neuropathic pain .
    Carbamazepine (Standard)
  • HY-D1755
    Fluo-3FF AM

    		Fluorescent Dye Others
    Fluo-3FF AM is a low affinity (Kd = 42 μM) fluorescent Ca 2+ sensitive indicator (Abs/Em = 462 nm/526 nm). Fluo-3FF AM is Mg 2+ insensitive and relatively photostable. Fluo-3FF AM is an analog of Fluo-3FF AM. Fluo-3FF AM is essentially non-fluorescent, but exhibits a strong fluorescence enhancement upon entry into cells and binding to calcium.
    Fluo-3FF AM
  • HY-107543
    8-CPT-2Me-cAMP sodium

    		Ras Others
    8-CPT-2Me-cAMP sodium is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50> 10 μM) . 8-CPT-2Me-cAMP sodium stimulates Epac-mediated Ca 2+ release in pancreatic β-cells in vitro .
    8-CPT-2Me-cAMP sodium

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