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AZA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (3) Apoptosis (5) Bacterial (1) Biochemical Assay Reagents (1) DNA Methyltransferase (3) Epigenetic Reader Domain (1) ERK (1) Fluorescent Dye (4) GnRH Receptor (1) HuR (1) Legumain (1) Microtubule/Tubulin (1) Nucleoside Antimetabolite/Analog (14) PAK (1) Parasite (1) Ras (2)
By Research Areas:	Cancer (21) Endocrinology (2) Infection (1) Inflammation/Immunology (1) Metabolic Disease (1)
Click Chemistry:	Azide (3)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136383

AZA1 1 Publications Verification Rac1/Cdc42-IN-1	Ras Apoptosis	Cancer
AZA1 is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induces prostate cancer cells apoptosis and inhibits prostate cancer cells proliferation, migration and invasion .

HY-10222

Ixabepilone 4 Publications Verification BMS-247550; AZA-epothilone B	Microtubule/Tubulin Apoptosis Bacterial	Cancer
Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis.

HY-116269

AZA197	Ras Apoptosis PAK ERK	Cancer
AZA197 is a selective small molecule inhibitor of *Cdc42*.AZA197 suppresses colon cancer cell proliferation, cell migration, invasion and increases apoptosis by down-regulating the PAK1 and ERK signaling pathways in vitro. AZA197 reduces tumor growth and significantly increases mouse survival in SW620 tumor xenografts .

HY-124844

Azaphilone-9 AZA-9	HuR	Cancer
Azaphilone-9 (AZA-9) is an inhibitor of HuR-ARE RNA interaction (IC₅₀=1.2 μM) by binding RNA-binding protein Hu antigen R (HuR). The HuR-RNA interactions stabilize many oncogenic mRNAs in tumors. Thus Azaphilone-9 potentially inhibit cancer cell growth and progression .

HY-139015

*5-Aza-4'-thio-2'-deoxycytidine* 5-AZA-T-dCyd; NTX-301	DNA Methyltransferase	Cancer
5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd) is an orally active DNA methyltransferase I (DNMT1) inhibitor. 5-Aza-4'-thio-2'-deoxycytidine, a sulfur-containing deoxy-cytidine analog, has the potential for DNA hypomethylating and has antitumor effects .

HY-111627

*5-Aza-7-deazaguanine* 1 Publications Verification	Nucleoside Antimetabolite/Analog	Cancer
5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides .

HY-18005

4-Aza-Oleanolic acid methyl ester

Others Others

4-Aza-Oleanolic acid methyl ester is a triterpenic derivative .

*4-Aza-Oleanolic acid methyl ester*	Others	Others
4-Aza-Oleanolic acid methyl ester is a triterpenic derivative .

HY-152743

*8-Aza-7-deazguanosine*	Nucleoside Antimetabolite/Analog	Cancer
8-Aza-7-deazguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154470

*8-Aza-2’-deoxyguanosine*	Nucleoside Antimetabolite/Analog	Cancer
8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154399

*5-Aza-3’-deoxycytidine*	Nucleoside Antimetabolite/Analog	Cancer
5-Aza-3’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154120

*6-Aza-2'-deoxyuridine*	Nucleoside Antimetabolite/Analog	Cancer
6-Aza-2'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-D1186

*2-Aza-ε-adenosine* 2-AZA-1,N6-ethenoadenosine	Fluorescent Dye	Others
2-Aza-ε-adenosine (2-Aza-1,N6-ethenoadenosine) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-154400

*5-Aza-3’-beta-methylcytidine*	Nucleoside Antimetabolite/Analog	Cancer
5-Aza-3’-beta-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-151763

Boc-L-Aza-OH (CHA)

ADC Linker Others

Boc-L-Aza-OH CHA is a click chemistry reagent containing an azide group.

*Boc-L-Aza-OH (CHA)*	ADC Linker	Others
Boc-L-Aza-OH CHA is a click chemistry reagent containing an azide group.

HY-152467

*8-Aza-2’-beta-C-methylguanosine*	Nucleoside Antimetabolite/Analog	Cancer
8-Aza-2’-beta-C-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152733

*8-Aza-7-bromo-7-deazaguanosine*	Nucleoside Antimetabolite/Analog	Cancer
8-Aza-7-bromo-7-deazaguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152831

*2-Amino-8-aza-7-deaza-7-iodoguanosine*	Nucleoside Antimetabolite/Analog	Cancer
2-Amino-8-aza-7-deaza-7-iodoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154398

*5-Aza-xylo-cytidine*	Nucleoside Antimetabolite/Analog	Cancer
5-Aza-xylo-cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-151784

*Boc-D-Aza-OH*	ADC Linker	Others
Boc-D-Aza-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .

HY-155868

5-Azacytidine 5′-triphosphate 5-AZA-CTP	Others	Others
5-Azacytidine 5′-triphosphate (5-aza-CTP) is a cytidine analog that inhibitss the incorporation of [ ³H]CTP, but not [ ³H]UTP, into RNA in the DNA-dependent RNA polymerase reaction .

HY-W419403

*Boc-D-Aza-OH (CHA)*	ADC Linker	Others
Boc-D-Aza-OH (CHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .

HY-D1187

*2-Aza-ε-cAMP*	Fluorescent Dye	Others
2-Aza-ε-cAMP is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D1187A

*2-Aza-ε-cAMP sodium*	Fluorescent Dye	Others
2-Aza-ε-cAMP (sodium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-154359

*2’-O-Acetyl-3’,5’-bis-O-benzoyl-6-aza-xylo uridine*	Nucleoside Antimetabolite/Analog	Cancer
2’-O-Acetyl-3’,5’-bis-O-benzoyl-6-aza-xylo uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-110044

MNITMT

Others Inflammation/Immunology

MNITMT is a more potent immunosuppressive agent without bone marrow toxicity .

MNITMT	Others	Inflammation/Immunology
MNITMT is a more potent immunosuppressive agent without bone marrow toxicity .

HY-112205A

RR-11a analog 4 Publications Verification	Parasite Legumain	Infection
RR-11a analog is a potent and irreversible inhibitor of Schistosoma mansoni legumain, with an IC₅₀ of 31 nM. RR-11a analog is an aza-Asn derivative and aza-peptide Michael acceptor .

HY-50071

6-Amino-5-nitropyridin-2-one	Nucleoside Antimetabolite/Analog	Others
6-Amino-5-nitropyridin-2-one is a pyridine base and used as a nucleobase of hachimoji DNA, in which it pairs with 5-aza-7-deazaguanine .

HY-A0004

Decitabine Maximum Cited Publications 92 Publications Verification 5-AZA-2'-deoxycytidine; 5-AZA-CdR; NSC 127716	DNA Methyltransferase Apoptosis Nucleoside Antimetabolite/Analog	Cancer
Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity .

HY-P4693

(Ser(tBu)6,Azagly10)-LHRH

GnRH Receptor Endocrinology

(Ser(tBu)6,Azagly10)-LHRH is a potent aza-GLY analog .

(Ser(tBu)6,Azagly10)-LHRH	GnRH Receptor	Endocrinology
(Ser(tBu)6,Azagly10)-LHRH is a potent aza-GLY analog .

HY-W007656

Cyclen	Others	Others
Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates .

HY-A0004R

Decitabine (Standard) 5-AZA-2'-deoxycytidine (Standard); 5-AZA-CdR (Standard); NSC 127716 (Standard)	DNA Methyltransferase Apoptosis Nucleoside Antimetabolite/Analog	Cancer
Decitabine (Standard) is the analytical standard of Decitabine. This product is intended for research and analytical applications. Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity .

HY-D1452

BDP-4

Fluorescent Dye Cancer

BDP-4 is an amino acid-modified near-infrared Aza-BODIPY photosensitizer, acts as an immune initiator for potent photodynamic research in melanoma .

BDP-4	Fluorescent Dye	Cancer
BDP-4 is an amino acid-modified near-infrared Aza-BODIPY photosensitizer, acts as an immune initiator for potent photodynamic research in melanoma .

HY-155868A

5-Azacytidine 5′-triphosphate sodium 5-AZA-CTP sodium	Others	Others
5-Azacytidine 5’-triphosphate sodium is a cytidine analog. 5-Azacytidine 5’-triphosphate sodium inhibits the incorporation of [ ³H]CTP, but not [ ³H]UTP, into RNA in the DNA-dependent RNA polymerase reaction .

HY-D1453

Immune initiator-1	Biochemical Assay Reagents	Cancer
Immune initiator-1 (Compound 1a) is an amino acid-modified near-infrared Aza-BODIPY photosensitizer, acts as an immune initiator for potent photodynamic research in melanoma .

HY-139076

Menin-MLL inhibitor 19	Epigenetic Reader Domain	Metabolic Disease Cancer
Menin-MLL inhibitor 19, a potent exo-aza spiro inhibitor of menin-mll interaction, example A17, extracted from patent WO2019120209A1. Menin-MLL inhibitor 19 can be used for the reseaech of various diseases, such as cancer, myelodysplastic syndrome (MDS) and diabetes .

Cat. No.	Product Name	Type

HY-D1186

*2-Aza-ε-adenosine* 2-AZA-1,N6-ethenoadenosine	Dyes
2-Aza-ε-adenosine (2-Aza-1,N6-ethenoadenosine) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

2-Aza-ε-adenosine

2-AZA-1,N6-ethenoadenosine

Dyes

2-Aza-ε-adenosine (2-Aza-1,N6-ethenoadenosine) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D1187

*2-Aza-ε-cAMP*	Dyes
2-Aza-ε-cAMP is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

2-Aza-ε-cAMP

Dyes

2-Aza-ε-cAMP is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D1187A

*2-Aza-ε-cAMP sodium*	Dyes
2-Aza-ε-cAMP (sodium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

2-Aza-ε-cAMP sodium

Dyes

2-Aza-ε-cAMP (sodium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

KISS1-305	Peptides	Endocrinology
KISS1-305, the Metastin/Kisspeptin analog, is a prototype peptide and a chemical probe. KISS1-305 has suboptimal KISS1R agonistic activity, and resists plasma protease degradation .

(Ser(tBu)6,Azagly10)-LHRH	GnRH Receptor	Endocrinology
(Ser(tBu)6,Azagly10)-LHRH is a potent aza-GLY analog .

Cyclen	Natural Products Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields Menispermaceae Stephania japonica (Thunb.) Miers	Others
Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates .

*Boc-L-Aza-OH (CHA)*		Azide
Boc-L-Aza-OH CHA is a click chemistry reagent containing an azide group.

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AZA

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