Glucosidase

Related Products

Glucosidases are glycoside hydrolase enzymes. α-glucosidase is a glucosidase located in the brush border of the small intestine that acts upon α(1→4) bonds. α-Glucosidase inhibitor is a new type of antidiabetics. By reducing the postprandial blood sugar concentration, it can effectively control the blood sugar levels, thereby reducing the occurrence of diabetic complications.

β-glucosidase catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues in β-D-glucosides and oligosaccharides, with release of glucose. β-Glucosidase has attracted substantial attention in the scientific community because of its pivotal role in cellulose degradation, glycoside transformation and many other industrial processes. β-glucosidases catalyze the final step of cellulose hydrolysis and are essential in cellulose degradation.

Glucosidase Related Products (225)
Antibodies (3)

By Effects:	Inhibitors (196) Activators (9) Modulators (3) Chemical (1) Inducer (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-N4258

Panasenoside	Inhibitor	99.93%
Panasenoside is a flavonoid isolated from Lilium pumilum DC. Panasenoside exhibits α-glucosidase inhibitory activity.

HY-B1039AS

Ambroxol-d₅ hydrochloride	Activator	99.46%
Ambroxol-d₅ (hydrochloride) is the deuterium labeled Ambroxol hydrochloride. Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the proagent Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research[1][2].

HY-N3431

Kaempferol-7-O-rhamnoside	Inhibitor	≥99.0%
Kaempferol-7-O-rhamnoside, isolated from Chimonanthus nitens Oliv. Leaves, is a potent α-glucosidase activity inhibitor. Kaempferol-7-O-rhamnoside has the potential for diabetes.

HY-N7763

Casuarictin	Inhibitor	98.62%
Casuarictin is a potent and competitive α-glucosidase inhibitor with an IC₅₀ of 0.21 μg/mL. Casuarictin is a presenilin stabilization factor like protein (PSFL) protein inhibitor. Casuarictin can be used for Alzheimer's disease research.

HY-N2383

Validamine	Inhibitor
Validamine competitively inhibits β-glucosidase in a pH-dependent and dose-dependent manner, with an IC₅₀ value of 2.92mM, and the maximum inhibitory ability is at the optimum pH value of this enzyme.

HY-N10413

Diphlorethohydroxycarmalol	Inhibitor	98.46%
Diphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and α-amylase inhibitor with IC₅₀s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities.

HY-N2223

Ganoderol B	Inhibitor
Ganoderol B is a potent α-glucosidase inhibitor. Ganoderol B has high α-glucosidase inhibition with an IC₅₀ of 48.5 μg/mL (119.8 μM).

HY-125713

Ganoderic acid Y	Inhibitor	99.07%
Ganoderic acid Y is a α-glucosidase inhibitor with an IC₅₀ of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating.

HY-N1839

3-Hydroxybakuchiol	Inhibitor
3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC₅₀: 345 μM).

HY-145274

EB-0156	Inhibitor
EB-0156 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC₅₀s of 0.0479 and less than 0.001 μM, respectively. EB-0156 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0156 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses.

HY-150560

α-Glucosidase-IN-11	Inhibitor
α-Glucosidase-IN-11 is a highly permeable competitive α-glucosidase inhibitor with the IC₅₀ value of 0.56 μM. α-Glucosidase-IN-11 binds to Trp residues in α-glucosidase and regulates protein folding. α-Glucosidase-IN-11 can be used to regulate blood glucose levels.

HY-N10606

Uvagrandol	Inhibitor
Uvagrandol potently inhibits α-glucosidase and porcine lipase (IC₅₀: 15.2 μM, 11.2 μM respectively). Uvagrandol can be used in the research of Type 2 diabetes and obesity.

HY-146156

α-Glucosidase-IN-7	Inhibitor
α-Glucosidase-IN-7 is a noncompetitive α-glucosidase inhibitor with an IC₅₀ value of 18.9 µM.

HY-149557

α-Amylase/α-Glucosidase-IN-5	Inhibitor
α-Amylase/α-Glucosidase-IN-5 (compound 4l) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC₅₀s of 5.96 μM and 1.62 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity.

HY-147823

α-Glucosidase-IN-6	Inhibitor
α-Glucosidase-IN-6 (compound 18) is a competitive α-glucosidase inhibitor with an IC₅₀ of 5.69 µM. α-Glucosidase-IN-6 has anti-diabetic potential.

HY-N12138

Flaccidoside III	Inhibitor
Flaccidoside III is a flavonoid and triterpenoid isolated from the aerial parts of N. sativa (Ranunculaceae). Flaccidoside III inhibits α-Glucosidase (IC₅₀: 256.7 μM) and has potential antioxidant and antidiabetic activities.

HY-161355

α-Amylase/α-Glucosidase-IN-9	Inhibitor
α-Amylase/α-Glucosidase-IN-9 (compound 5h) is a dual inhibitor for both α-amylase (IC₅₀ = 16.4 μM) and α-glucosidase (IC₅₀ = 31.6 μM) enzymes.

HY-N12688

2,3-Dihydrocalodenin B	Inhibitor
2,3-Dihydrocalodenin B (Compound 6) is a compound that can be isolated from Knema globularia. 2,3-Dihydrocalodenin B is a potent and non-competitive inhibitor against α-glucosidase and α-amylase, with IC₅₀ values of 1.1 and 2.6 μM, respectively. 2,3-Dihydrocalodenin B can be used for the research of diabetes.

HY-N10440

3-Oxo-hop-22(29)-ene	Inhibitor
3-Oxo-hop-22(29)-ene is a yeast α-glucosidase inhibitor. 3-Oxo-hop-22(29)-ene shows a moderate effect on the viability of T. cruzi and L. mexicana. 3-Oxo-hop-22(29)-ene shows marginal activity of anti-inflammatory.

HY-146305

α-Glucosidase-IN-4	Inhibitor
α-Glucosidase-IN-4 is a reversible and mixed type α-glucosidase inhibitor with an IC₅₀ of 12.98 μM, a K_I of 27.02 μM, and a K_IS of 13.65 μM, respectively.

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Glucosidase

Glucosidase

Glucosidase Related Products (225)

Antibodies (3)

Glucosidase Related Products (225):