2. Apoptosis
  3. Apoptosis
  4. WLSEAGPVVTVRALRGTGSW

WLSEAGPVVTVRALRGTGSW is a cardiomyocyte specific peptide. WLSEAGPVVTVRALRGTGSW-expressing exosomes can improve specific uptake by cardiomyocytes, decrease cardiomyocyte apoptosis, and enhance cardiac retention following intramyocardial injection in vivo.

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WLSEAGPVVTVRALRGTGSW Chemical Structure

WLSEAGPVVTVRALRGTGSW Chemical Structure

CAS No. : 771479-86-8

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Based on 1 publication(s) in Google Scholar

Other Forms of WLSEAGPVVTVRALRGTGSW:

WLSEAGPVVTVRALRGTGSW Related Antibodies

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Description

WLSEAGPVVTVRALRGTGSW is a cardiomyocyte specific peptide. WLSEAGPVVTVRALRGTGSW-expressing exosomes can improve specific uptake by cardiomyocytes, decrease cardiomyocyte apoptosis, and enhance cardiac retention following intramyocardial injection in vivo[1][2].

Molecular Weight

2142.42

Formula

C97H152N28O27
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

WLSEAGPVVTVRALRGTGSW
SMILES

[WLSEAGPVVTVRALRGTGSW]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (46.68 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4668 mL 2.3338 mL 4.6676 mL
5 mM 0.0934 mL 0.4668 mL 0.9335 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4668 mL 2.3338 mL 4.6676 mL 11.6690 mL
5 mM 0.0934 mL 0.4668 mL 0.9335 mL 2.3338 mL
10 mM 0.0467 mL 0.2334 mL 0.4668 mL 1.1669 mL
15 mM 0.0311 mL 0.1556 mL 0.3112 mL 0.7779 mL
20 mM 0.0233 mL 0.1167 mL 0.2334 mL 0.5835 mL
25 mM 0.0187 mL 0.0934 mL 0.1867 mL 0.4668 mL
30 mM 0.0156 mL 0.0778 mL 0.1556 mL 0.3890 mL
40 mM 0.0117 mL 0.0583 mL 0.1167 mL 0.2917 mL
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WLSEAGPVVTVRALRGTGSW Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WLSEAGPVVTVRALRGTGSW771479-86-8Apoptosiscardiomyocyteexosomesapoptosiscardiac retentionInhibitorinhibitorinhibit

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