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  4. Tc-Me2P

Tc-Me2P is a 99MTC-labeled acrylamide (PnAO) derivative that contains two 4-methyl-2-nitroimidazole groups. The primary activity of Tc-Me2P is as an imaging agent for tumor hypoxia. By specifically binding to hypoxic regions in tumor tissue, it can be used for single photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging to detect hypoxia in tumors. Tc-Me2P can be used to study the targeting of different chemical structures in tumors and normal tissues.

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Tc-Me2P Chemical Structure

Tc-Me2P Chemical Structure

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Tc-Me2P Related Antibodies

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Description

Tc-Me2P is a 99MTC-labeled acrylamide (PnAO) derivative that contains two 4-methyl-2-nitroimidazole groups. The primary activity of Tc-Me2P is as an imaging agent for tumor hypoxia. By specifically binding to hypoxic regions in tumor tissue, it can be used for single photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging to detect hypoxia in tumors. Tc-Me2P can be used to study the targeting of different chemical structures in tumors and normal tissues[1].

Molecular Weight

634.44

Formula

C21H31N10O7Tc
SMILES

O=[Tc]123N4CCCN1C(C)(C)C(CN5C=C(C)N=C5[N+]([O-])=O)=[N]2O[H]O[N]3=C(CN6C=C(C)N=C6[N+]([O-])=O)C4(C)C
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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Tc-Me2P Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tc-Me2POthersImaging agentPETSPECTTumor hypoxiaTargetingInhibitorinhibitorinhibit

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