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Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues .
Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables . Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions .
Thiotraniliprole (HY366) is an ortho formamidobenzamide insecticide that can be used for the synthesis of insecticidal combinations. Thiotraniliprole has potential applications in the prevention of lepidoptera pests, coleoptera pests, ants, and termites .
Insecticidal agent 6 (Compound Im) is an insect ryanodine receptors (RyRs) inhibitor, with an EC50 value of 0.6308 µM against S. frugiperdaRyRs. Insecticidal agent 6 has excellent insecticidal activity against lepidopteran pests and can be used for research on pests and diseases .
(R)-Dinotefuran ((R)-MTI-446), a neonicotinoid pesticide, exhibits comparative insecticidal activities (1.7-2.4 times) to typical sucking pestsAphis gossypii and Apolygus lucorum compared to racemic mixtures by inhibiting nicotinic acetylcholine receptors. (R)-Dinotefuran has a good efficacy in controlling target pests while minimizing hazard to honeybees .
Calarene is an insecticide that can be obtained from the stem of Kadsura heteroclite. Calarene is toxic to Meloidogyne incognita, Sitophilus zeamais, and mosquitoes. Calarene can be used in the research of plant pests and mosquito control .
Azadirachtin, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4 .
D-Phenothrin ((-)-trans-Phenothrin), an orally active Type II synthetic pyrethroid, is widely used to kill insects, mosquitoes, and human lice. D-Phenothrin is also used in veterinary medicine to control insect pests on animals and protect agricultural crops .
Insecticidal agent 9 (Compound I-17) is an insecticide with good insecticidal activity. Insecticidal agent 9 has LC50 values of 93.32 mg/L and 114.79 mg/L against Plutella xylostella and Ostrinia furnacalis respectively, and exhibits a mortality rate of up to 86.1% against Spodoptera frugiperda at a concentration of 500 mg/L. Insecticidal agent 9 can act simultaneously on the ecdysone receptor (EcR) and three chitinases (OfChtI, OfChtII, and OfChi-h), demonstrating good binding activity (to EcR) and inhibitory rates (to the three chitinases). Insecticidal agent 9 can be used in research for pest management .
Chitinase-IN-5 (8i) is a potent chitinase OfChi-h inhibitor with an IC50 value of 0.051 μM. Chitinase-IN-5 shows good insecticidal activity, it can be used for the research of green pest control and management .
Insecticidal agent 3 is a multichitinase inhibitors, belongs to insect growth regulators (IGRs),with Kis of 0.8μM, 11.9 μM, and 2.3 μM for Of ChtI, Of ChtII, and Of Chi-h, respectively. Insecticidal agent 3 exhibits insecticidal activity against two lepidopteran pests by interfering with normal insect growth and molting .
Chlorfenapyr is a pyrrole insecticide. Chlorfenapyr has a mode of action: the mixed function oxidase oxidizes and removes the Nethoxymethyl group to form the active metabolite, CL 303268. Chlorfenapyr is used for termite control and crop protection against a variety of insect and mite pests .
Chitinase-IN-4 (compound 8f), an azo-aminopyrimidine derivative, is a potent, selective OfChi-h inhibitor with an IC50 value of 0.1 μM. Chitinase-IN-4 has good insecticidal activity. Chitinase-IN-4 can be used in research of green pest control and management .
Callosobruchusic acid (R-(-)-Callosobruchusic acid) is an active compound in sex pheromone of the bean pestCallosobruchus chinensis L. Callosobruchusic acid can be used in pest control strategy development .
Notrilobolide is an alkaloid with insecticidal properties isolated from sweet potatoes. Notrilobolide has an inhibitory effect on the larval development of pests such as Tribolium Castaneum, affecting the digestion and reproduction of insects by inhibiting the fecundity of pests .
Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research .
Tetradecyl acetate is a sex pheromone produced by Ctenopseustis obliquana females. Tetradecyl acetate can be used to disrupt the mating of pest species .
Flufiprole is a nonsystemic phenylpyrazole insecticide targeting the GABA receptor used in the rice field. Flufiprole is excellent in controlling a wide range of pests .
Flupyradifurone is a systemic nAChR agonist that interferes with signal transduction in the central nervous system of sucking pests. Flupyradifurone can be used as a butenolide insecticide .
Transfluthrin is a fast-acting pyrethroid insecticide and mosquito repellent. Transfluthrin is against flying insects, such as mosquito and flies, and in agriculture material pests .
Bistrifluron has insecticidal effects on the larval stage, and also has an effect on adult longevity, reproduction, and hatchability. Bistrifluron is used for the control of a variety of Lepidopterous pests .
Tetramethrin (Standard) is the analytical standard of Tetramethrin. This product is intended for research and analytical applications. Tetramethrin is a synthetic pyrethroid insecticide for use on a broad spectrum of insect pests .
Famoxadone (DPX-JE874) is a fungicide acting against a broad spectrum of fungi and is widely used in Integrated Pest Management strategies in different agricultural crops .
Chlorfluazuron (IKI-7899) is a benzoylurea insecticide. Chlorfluazuron inhibts insect chitin and disrupts normal exuviation by inducing malformations, thereby preventing and controlling lepidopteranpests .
Imidacloprid (Standard) is the analytical standard of Imidacloprid. This product is intended for research and analytical applications. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton.
Imidacloprid-d4 is the deuterium labeled Imidacloprid[1]. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton[2].
(E)-Cinnamamide, the less active isomer of Cinnamamide. Cinnamamide, a derivative of the plant secondary compound Cinnamic acid. Cinnamamide is effective as a non-lethal chemical repellent suitable for reducing avian pest damage .
ZK-PI-5 is a potent trehalase inhibitor and regulate the reproduction of Spodoptera frugiperda. ZK-PI-5 has the potential to be a?new insecticide and has pest control potential .
Dicloromezotiaz is a potent insecticide acting on nicotinic acetylcholine receptors (nAChRs). Dicloromezotiaz can be used to control a broad range of lepidoptera .
Pyridalyl (S 1812) is an insecticides against Lepidoptera and Thrips. Pyridalyl is less toxic to some beneficial arthropods, and non-target organisms, such as mammals and fish, and thus be utilized in integrated pest management and resistance management .
3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants .
Bensultap (Bancol) is an insecticide, which can control Colorado beetle and some other insect pests. Bensultap is a modulator for nicotinic acetylcholine receptor (nAChR), and exhibits mild and temporary neuromodulatory efficacy on rat nervous system .
Fenpyroximate is an acaricide and insecticide against many mites and insect pests of agricultural crops and ornamentals. Fenpyroximate is also a strong inhibitor of bovine heart mitochondrial NADH-ubiquinone oxidoreductase (complex I), binds to the ND5 subunit .
Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects .
Imidacloprid-urea is a metabolite of Imidacloprid. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton. Imidacloprid-urea can occupy or block adsorption sites of imidacloprid on soil, potentially affecting the fate, transport, and bioavailability of imidacloprid in the environment .
Iodofenphos (Jodfenphos) is an insecticide, that can be used as a protectant for stored grains. Iodofenphos is effective against grain pests, such as Sitophilus oryzae, Tribolium castaneum, and larvae of Trogoderma granarium, and has a significant residual toxicity, which could provide good insect control for several months .
Clothianidin is a neonicotinoid insecticide. Clothianidin shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin has various application methods and high safety for crops .
Tebufenozide-d9 is the deuterium labeled Tebufenozide[1]. Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells[2][3].
Tebufenozide (Standard) is the analytical standard of Tebufenozide. This product is intended for research and analytical applications. Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
(3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate is a sex pheromone capable of attracting male South American tomato pinworms (Scrobipalpuloides absoluta), which can be isolated from the tomato pest .
Laburnetin is a kind of isoflavone antibacterial agent. Laburnetin has antibacterial activity against fungi and S. vesicarium. Laburnetin intensifies the susceptibility of Methicillin (HY-121544) resistant Staphylococcus aureus (MRSA) strains to Methicillin. Laburnetin can be used to control pests of cultivated species .
Triadimefon is a triazole fungicide used to control powdery mildew, rusts, and other fungal pests on grains, fruit and vegetable crops, turf, shrubs, and trees. Triadimefon inhibits lanosterol 14α-demethylase, interfering with oxidative demethylation reactions in the ergosterol biosynthesis pathway of fungi, and also blocks gibberellin biosynthesis.
Dimethoate-d6 is the deuterium labeled Dimethoate. Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects[1].
Indoxacarb ((±)-Indoxacarb; DPX-JW062) is a broad-spectrum oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. Indoxacarb blocks insect sodium channels (Sodium Channel) in nerve preparations and isolated neurons .
λ-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. λ-Cyhalothrin is used to control a wide range of pests in a variety of applications. λ-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system .
Thiacloprid-d4 is the deuterium labeled Thiacloprid[1]. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables[1]. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions[2].
Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .
3-Pentanol-d5 is the deuterium labeled 3-Pentanol[1]. 3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants[2].
Isocycloseram is an isoxazoline insecticide and acaricide widely recognized as an allosteric modulator of GABA-gated chloride channels. Isocycloseram is active against Lepidopteran, Hemiptera, Coleoptera, Thysanoptera and Diptera pests. Isocycloseram targets the invertebrate Rdl GABA receptor, but the G335M mutation in the third transmembrane domain of the Rdl GABA receptor may mediate resistance .
Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .
Deltamethrin (Decamethrin) is an orally active synthetic pyrethroid insecticide. Deltamethrin induces oxidative stress and results in inflammation and apoptosis via inhibiting Nrf2/HO-1 pathway. Deltamethrin has an anticancer effect by inducing apoptosis. Deltamethrin can be used extensively in pest control .
J9Z38 is a metabolite of Cyantraniliprole (HY-12779), a broad-spectrum agrochemical insecticide belonging to the anthranilic diamide insecticide class. Cyantraniliprole effectively controls the growth of various pests on fruits, vegetables, cereals and other crops. Thus, J9Z38 is a key indicator for indirect detection and evaluation of Cyantraniliprole residue levels .
Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity . Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L .
7(Z)-Pentacosene is an aggregation pheromone of the European earwig (Forficula auricularia). 7(Z)-Pentacosene can be used in the study of insect behavior and neurobiology .
Buprofezin-d6 is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase[1][2].
Clothianidin-d3 is the deuterium labeled Clothianidin.Clothianidin-d3 is a neonicotinoid insecticide. Clothianidin-d3 shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin-d3 has various application methods and high safety for crops .
Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture,veterinary, insecticide,pyrethroid and stored product .
Z13,YN11-16:OH (7) is an insect pheromone used for attracting and trapping processionary caterpillars (Thaumetopoea processionea L), effective against oak defoliators .
3,7-Dimethyloctan-1-ol, 3,7-Dimethyloctan-1-ol is commonly used as a flavor and fragrance ingredient due to its pleasant aroma, it can also be used as a solvent, and in the synthesis of various organic compounds (including pharmaceuticals and agrochemicals), in addition, due to its high energy content and low volatility, 3,7-Dimethyloctan-1-ol has been investigated for its potential use as a biofuel, due to its toxicity to some pests, it has also been studied as a potential repellent and insecticide,
(Z,E)-9,12-Tetradecadienal (Z9,E12-14:Ald) is a female pheromone that can induce an electroantennographic response in male antennae, isolated from the sex pheromone extracts of Plodia interpunctella (lepidoptera: pyralidae) .
Pesticide is a single substance or mixture that can be used to prevent, mitigate, iminate pests or as a plant conditioner, defoliant or desiccant. In recent years, scientists have proposed the concept of "Molecules to Ecosystems", bringing the concept of molecular biology to understand the impact of pesticides, degradation and relationship with the environment or organisms. MCE integrates effective compounds approved as pesticides by agencies such as the Environmental Protection Agency (EPA) and some insecticidal compounds with potential for agricultural applications.
MCE can provide a library of 246 pesticide compounds that are tool compounds for relevant research.
3,7-Dimethyloctan-1-ol, 3,7-Dimethyloctan-1-ol is commonly used as a flavor and fragrance ingredient due to its pleasant aroma, it can also be used as a solvent, and in the synthesis of various organic compounds (including pharmaceuticals and agrochemicals), in addition, due to its high energy content and low volatility, 3,7-Dimethyloctan-1-ol has been investigated for its potential use as a biofuel, due to its toxicity to some pests, it has also been studied as a potential repellent and insecticide,
Azadirachtin, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4 .
Calarene is an insecticide that can be obtained from the stem of Kadsura heteroclite. Calarene is toxic to Meloidogyne incognita, Sitophilus zeamais, and mosquitoes. Calarene can be used in the research of plant pests and mosquito control .
Notrilobolide is an alkaloid with insecticidal properties isolated from sweet potatoes. Notrilobolide has an inhibitory effect on the larval development of pests such as Tribolium Castaneum, affecting the digestion and reproduction of insects by inhibiting the fecundity of pests .
Tetradecyl acetate is a sex pheromone produced by Ctenopseustis obliquana females. Tetradecyl acetate can be used to disrupt the mating of pest species .
(E)-Cinnamamide, the less active isomer of Cinnamamide. Cinnamamide, a derivative of the plant secondary compound Cinnamic acid. Cinnamamide is effective as a non-lethal chemical repellent suitable for reducing avian pest damage .
3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants .
(3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate is a sex pheromone capable of attracting male South American tomato pinworms (Scrobipalpuloides absoluta), which can be isolated from the tomato pest .
Laburnetin is a kind of isoflavone antibacterial agent. Laburnetin has antibacterial activity against fungi and S. vesicarium. Laburnetin intensifies the susceptibility of Methicillin (HY-121544) resistant Staphylococcus aureus (MRSA) strains to Methicillin. Laburnetin can be used to control pests of cultivated species .
Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .
Deltamethrin (Decamethrin) is an orally active synthetic pyrethroid insecticide. Deltamethrin induces oxidative stress and results in inflammation and apoptosis via inhibiting Nrf2/HO-1 pathway. Deltamethrin has an anticancer effect by inducing apoptosis. Deltamethrin can be used extensively in pest control .
Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity . Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L .
7(Z)-Pentacosene is an aggregation pheromone of the European earwig (Forficula auricularia). 7(Z)-Pentacosene can be used in the study of insect behavior and neurobiology .
Z13,YN11-16:OH (7) is an insect pheromone used for attracting and trapping processionary caterpillars (Thaumetopoea processionea L), effective against oak defoliators .
(Z,E)-9,12-Tetradecadienal (Z9,E12-14:Ald) is a female pheromone that can induce an electroantennographic response in male antennae, isolated from the sex pheromone extracts of Plodia interpunctella (lepidoptera: pyralidae) .
PTPN12 Protein, a versatile enzyme, dephosphorylates various proteins, regulating cellular signaling cascades. Documented in literature, PTPN12 selectively targets tyrosine kinases like ERBB2 and PTK2B/PYK2, exerting control over associated pathways. Notably, PTPN12's specificity is evident in dephosphorylating ERBB2 at specific tyrosine residues, such as 'Tyr-1112,' 'Tyr-1196,' and/or 'Tyr-1248.' Its intricate dephosphorylation activity underscores PTPN12's significance in modulating key signaling events and fine-tuning cellular responses within tyrosine kinase pathways. PTPN12 Protein, Human is the recombinant human-derived PTPN12 protein, expressed by Sf9 insect cells , with tag free. and with residual Gly-Pro in N-terminal (not related to functional changes) mutation. The total length of PTPN12 Protein, Human is 355 a.a., with molecular weight of ~41 kDa.
The PTPN12 protein is a multifunctional enzyme that can dephosphorylate a variety of proteins and regulate cell signaling cascades. According to literature, PTPN12 selectively targets tyrosine kinases such as ERBB2 and PTK2B/PYK2 to control related pathways. PTPN12 Protein, Human (sf9, His-GST) is the recombinant human-derived PTPN12 protein, expressed by Sf9 insect cells , with N-GST, N-His labeled tag. The total length of PTPN12 Protein, Human (sf9, His-GST) is 355 a.a., with molecular weight of ~64 kDa.
The SLC16A2 protein is a specific thyroid hormone transmembrane transporter that promotes bidirectional movement of thyroid hormone across cell membranes independent of pH or Na(+) gradients. SLC16A2 has a significant preference for substrates such as T3 and T4 and is a key mediator of thyroid hormone transport. SLC16A2 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC16A2 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC16A2 Protein, Human (Sf9, His, MBP, FLAG) is 538 a.a., .
Dimethoate-d6 is the deuterium labeled Dimethoate. Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects[1].
Imidacloprid-d4 is the deuterium labeled Imidacloprid[1]. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton[2].
Tebufenozide-d9 is the deuterium labeled Tebufenozide[1]. Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells[2][3].
Thiacloprid-d4 is the deuterium labeled Thiacloprid[1]. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables[1]. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions[2].
3-Pentanol-d5 is the deuterium labeled 3-Pentanol[1]. 3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants[2].
Buprofezin-d6 is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase[1][2].
Clothianidin-d3 is the deuterium labeled Clothianidin.Clothianidin-d3 is a neonicotinoid insecticide. Clothianidin-d3 shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin-d3 has various application methods and high safety for crops .
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