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Results for "

mRNA delivery

" in MedChemExpress (MCE) Product Catalog:

53

Inhibitors & Agonists

28

Biochemical Assay Reagents

4

Peptides

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148049
    TT3

    		Liposome Others
    TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery .
    TT3
  • HY-153879
    C12-TLRa

    		Liposome Infection
    C12-TLRa is an adjuvant lipidoid. C12-TLRa acts as a structural component of LNP to enhance mRNA delivery. C12-TLRa substitution can increase antigen-specific antibody responses and B cell responses of clinically relevant mRNA-LNP vaccines .
    C12-TLRa
  • HY-153138
    FTT5 LLNs

    		Biochemical Assay Reagents Others
    FTT5 LLNs are functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing .
    FTT5 LLNs
  • HY-148363
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate

    		Liposome Inflammation/Immunology
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate
  • HY-W590679
    113-O16B

    		Liposome Others
    113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
    113-O16B
  • HY-151513
    Iso5-2DC18

    		Others Cancer
    Iso5-2DC18 is a lipid that can be used for the synthesis of amine containing lipids. These amine containing lipids can be used for mRNA delivery, activate the stimulator of interferon genes (STING) pathway, and exhibit anti-tumor immunity .
    Iso5-2DC18
  • HY-151512
    A12-Iso5-4DC19

    		Liposome Inflammation/Immunology Cancer
    A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .
    A12-Iso5-4DC19
  • HY-147354
    TriGalNAc CBz

    		LYTACs Cardiovascular Disease
    TriGalNAc CBz is a GalNAc derivative and tri-GalNAc is an asialoglycoprotein receptor (ASGPR) ligand. TriGalNAc CBz can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies .
    TriGalNAc CBz
  • HY-151509
    A2-Iso5-2DC18

    		Others Cancer
    A2-Iso5-2DC18 is a dihydroimidazole-linked lipid, served as potent mRNA delivery vehicle. A2-Iso5-2DC18 can be used for antitumor research, including B16F10 melanoma. .
    A2-Iso5-2DC18
  • HY-138170
    ALC-0315
    Maximum Cited Publications
    9 Publications Verification

    		 Liposome SARS-CoV Infection
    ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315
  • HY-145793
    FTT5

    		Others Others
    FTT5 is a lipid-like compound for efficient delivery of long mRNAs in vivo.
    FTT5
  • HY-138170A
    ALC-0315 (Excipient)

    		Liposome SARS-CoV Infection
    ALC-0315 Excipient is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 Excipient can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315 (Excipient)
  • HY-153380
    ALC-0315 analogue-2

    		Liposome Others
    ALC-0315 analogue-2 is an analogue of ALC-0315. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.
    ALC-0315 analogue-2
  • HY-145795
    OF-02

    		Liposome Others
    OF-02 is an alkenyl amino alcohol (AAA) ionizable lipid for highly potent in vivo mRNA delivery.
    OF-02
  • HY-138622
    24:0 Lyso PC

    		Liposome Others
    24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery .
    24:0 Lyso PC
  • HY-138622S1
    24:0 Lyso PC-d4

    		Isotope-Labeled Compounds Others
    24:0 Lyso PC-d44 is the deuterium labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].
    24:0 Lyso PC-d4
  • HY-W590548
    ATX-001

    		Liposome Others
    ATX-001 is an ionizable cationic lipid. ATX-001 can be used in the formation of lipid nanoparticles (LNPs) for the delivery mRNA .
    ATX-001
  • HY-138622S
    24:0 Lyso PC-13C6

    		Isotope-Labeled Compounds Others
    24:0 Lyso PC- 13C6 is the 13C labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].
    24:0 Lyso PC-13C6
  • HY-156985
    Lipid AX4

    		Isotope-Labeled Compounds Liposome Others
    Lipid AX4 is an ionizable cationic lipid with the pKa of 6.89， and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo .
    Lipid AX4
  • HY-138171
    Lipid 5

    		Liposome Others
    Lipid 5 is an amino lipid that affords efficient mRNA delivery in rodent and primate models. Lipid 5 shows optimal pharmacokinetics and non-toxic side effects .
    Lipid 5
  • HY-151511
    A12-Iso5-2DC18

    		Liposome Cancer
    A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
    A12-Iso5-2DC18
  • HY-46759
    Genevant CL1

    		Liposome Infection
    Genevant CL1 is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1][2].
    Genevant CL1
  • HY-46759A
    Genevant CL1 monohydrochloride

    		Liposome Infection
    Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .
    Genevant CL1 monohydrochloride
  • HY-W441014
    DSPE-PEG-NHS, MW 2000

    		Liposome Others
    DSPE-PEG-NHS, MW 2000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
    DSPE-PEG-NHS, MW 2000
  • HY-W441012
    DSPE-PEG-NHS, MW 600

    		Liposome Others
    DSPE-PEG-NHS, MW 600 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
    DSPE-PEG-NHS, MW 600
  • HY-W441016
    DSPE-PEG-NHS, MW 5000

    		Liposome Others
    DSPE-PEG-NHS, MW 5000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .
    DSPE-PEG-NHS, MW 5000
  • HY-W441015A
    DSPE-m-PEG-NHS (MW 3400)

    		Liposome Others
    DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
    DSPE-m-PEG-NHS (MW 3400)
  • HY-153371
    50-C2-C9-4tail

    		Liposome Others
    50-C2-C9-4tail has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo.
    50-C2-C9-4tail
  • HY-160580
    G1-OC2-K3-E10

    		Liposome Others
    G1-OC2-K3-E10 is an ionizable lipid, and can be used for delivery of mRNA in lipid nanoparticles (LNPs) .
    G1-OC2-K3-E10
  • HY-145405
    C12-200
    5 Publications Verification

    		 Liposome Others
    C12-200 is an ionizable cationic lipid and auxiliary lipid. C12-200 is commonly used for mRNA delivery. Administration of human erythropoietin (EPO) mRNA or factor VII siRNA increased and decreased serum factor VII levels, respectively, in LNPs mice containing C12-200 .
    C12-200
  • HY-160554
    C12-113

    		Liposome Infection Inflammation/Immunology
    C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice .
    C12-113
  • HY-164060
    LZCap AG(3'Acm) RLuc mRNA

    		Others Others
    Renilla luciferase (RLuc) is a novel luciferase enzyme with a size of 36 kD. RLuc catalyzes the oxidation reaction of coelenterazine under oxygen to emit fluorescence (maximum wavelength 480 nm). LZCap AG(3'Acm) RLuc mRNA is synthesized and purified in a one-step transcription process using T7 RNA polymerase and LZCap AG(3'Acm) cap analog from a linear template. This mRNA is suitable for experiments related to mRNA delivery, translation efficiency, transfection efficiency, and in vivo imaging.
    LZCap AG(3'Acm) RLuc mRNA
  • HY-148855
    OF-C4-Deg-Lin

    		Liposome Others
    OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA .
    OF-C4-Deg-Lin
  • HY-W590681
    113-O12B

    		Liposome Others
    113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
    113-O12B
  • HY-153231
    eGFP mRNA-LNP

    		Fluorescent Dye Liposome Others
    eGFP mRNA-LNP is a lipid nanoparticle (LNP) containing eGFP mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
    eGFP mRNA-LNP
  • HY-164058
    LZCap AG(3'Acm) RFP mRNA

    		Others Others
    Red fluorescent protein (RFP) is a protein isolated from the Pacific anemone (Discosoma sp.) that can emit red fluorescence under ultraviolet light. RFP can be excited by the 488 nm or 532 nm laser line and is optimally detected at 588 nm. LZCap AG(3'Acm) RFP mRNA is synthesized and purified in a one-step transcription process using T7 RNA polymerase and LZCap AG(3'Acm) cap analog. This mRNA is suitable for experiments related to mRNA delivery, translation efficiency, transfection efficiency, and in vivo imaging.
    LZCap AG(3'Acm) RFP mRNA
  • HY-W440896
    DSPE-PEG-SH, MW 2000

    		Liposome Others
    DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
    DSPE-PEG-SH, MW 2000
  • HY-158864
    BP Lipid 378

    		Liposome Others
    BP Lipid 378 is derived from patent WO2020219876A1 (Example 8). BP Lipid 378 is an ionizable amino lipid that features a unique pyrrolidine head group with a carbamate linkage to the lipid tails. This lipid may be used in the generation of lipid nanoparticles (LNPs) for mRNA delivery.
    BP Lipid 378
  • HY-W440909
    DSPE-PEG-Cy3, MW 3400

    		Liposome Others
    DSPE-PEG-Cy3, MW 3400 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy3, MW 3400
  • HY-W440910
    DSPE-PEG-Cy3, MW 5000

    		Liposome Others
    DSPE-PEG-Cy3, MW 5000 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy3, MW 5000
  • HY-W440913
    DSPE-PEG-Cy5, MW 5000

    		Liposome Others
    DSPE-PEG-Cy5, MW 5000 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy5, MW 5000
  • HY-W440912
    DSPE-PEG-Cy5, MW 3400

    		Liposome Others
    DSPE-PEG-Cy5, MW 3400 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy5, MW 3400
  • HY-153233
    CD19 car mRNA-LNP

    		CD19 Liposome Inflammation/Immunology Cancer
    CD19 car mRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car mRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car mRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .
    CD19 car mRNA-LNP
  • HY-164061
    LZCap AG(3'Acm) GLuc mRNA

    		Others Others
    Gaussia luciferase (GLuc) is the smallest known naturally secreted luciferase enzyme (20 kD) in vivo. When conducting fluorescence reporter experiments with Gaussia luciferase, detection can be directly performed using cell culture supernatant. This luciferase enzyme catalyzes the oxidation of coelenterazine to emit light (480 nm) without requiring ATP. LZCap AG(3'Acm) GLuc mRNA is synthesized and purified in a one-step transcription process using T7 RNA polymerase and LZCap AG(3'Acm) cap analog from a linear template. This mRNA is suitable for experiments related to mRNA delivery, translation efficiency, and transfection efficiency.
    LZCap AG(3'Acm) GLuc mRNA
  • HY-134541
    SM-102
    5+ Cited Publications

    		 Liposome Infection
    SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102
  • HY-134541A
    SM-102 (Excipient)

    		Liposome Infection
    SM-102 Excipient is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 Excipient has higher transfection efficiency. SM-102 Excipient plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102 (Excipient)
  • HY-158863
    BP Lipid 377

    		Liposome Others
    BP Lipid 377 is derived from patent WO2018062413A1. BP Lipid 377 is an ionizable amino lipid comprised of three linoleic acid tails and an N,N-dimethylamine head group four carbon atoms in length. This lipid may be used in the generation of lipid nanoparticles (LNPs) for mRNA and drug delivery.
    BP Lipid 377
  • HY-164059
    LZCap AG(3'Acm) mCherry mRNA

    		Others Others
    mCherry is a red fluorescent protein the derived from Discosoma sp.. mCherry has excitation/emission wavelengths of 587 nm/610 nm. LZCap AG(3'Acm) mCherry mRNA is synthesized and purified in a one-step transcription process using T7 RNA polymerase and LZCap AG(3'Acm) cap analog from a linear template. LZCap AG(3'Acm) generates a Cap1 structure mRNA post-transcription, providing more efficient and stable expression compared to Cap0 and other commercially available Cap1 structures. LZCap AG(3'Acm) mCherry mRNA contains poly A, optimized 5'UTR, and 3'UTR structures to improve mRNA stability and promote translation efficiency, resulting in enhanced expression. Upon entering cells, LZCap AG(3'Acm) mCherry mRNA expresses red fluorescence, suitable for experiments related to mRNA delivery, translation efficiency, transfection efficiency, and in vivo imaging.
    LZCap AG(3'Acm) mCherry mRNA
  • HY-W583869
    1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine

    1-Stearoyl-2-Oleoyl-sn-glycero-3-PE; 18:0-18:1 PE; PE(18:0/18:1)

    		 Liposome Metabolic Disease
    1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
    1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine
  • HY-145798
    N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide

    		Liposome Others
    N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3 (HY-148049). TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery .
    N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide

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