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lysosomal targeting chimeras (LYTACs)

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-158033
    Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn)

    		LYTACs Cancer
    Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn) (Compound 24) is a mannose-6-phosphate (M6Pn)-peptide conjugate capable of binding to targeted ligands of various proteins and successfully internalizing and degrading them through M6PR. Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 can be utilized in the research of lysosomal targeting chimeras (LYTACs) based on M6Pn .
    Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn)
  • HY-145368
    Tri-GalNAc-NHS ester

    		LYTACs Others
    Tri-GalNAc-NHS ester is a LYsosome TArgeting Chimera (LYTAC) and a ligand of asialoglycoprotein receptor (ASGPR). ASGPR is a lysosomal targeting receptor specifically expressed on liver cells, for the degradation of extracellular proteins including membrane proteins. Tri-GalNAc-NHS ester can be used as a protein degrader and it can be used for the research of LYTAC .
    Tri-GalNAc-NHS ester

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