helminths

By Targets:	Autophagy (2) Influenza Virus (2) Isotope-Labeled Compounds (1) Mitochondrial Metabolism (2) Parasite (7)
By Research Areas:	Cancer (2) Infection (7)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0217

Nitazoxanide 5+ Cited Publications NTZ; NSC 697855	Parasite Influenza Virus Autophagy	Infection Cancer
Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC₅₀ of 2.4 μM . Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .

HY-138502

Melarsomine	Parasite	Infection
Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections .

HY-138502A

Melarsomine dihydrochloride	Parasite	Infection
Melarsomine dihydrochloride is a trivalent arsenical compound used as an adulticide. Melarsomine dihydrochloride can be used for the reserach of canine heartworm disease and other helminth infections .

HY-158423

NPD8790	Mitochondrial Metabolism Parasite	Infection
NPD8790 is a species selective mitochondrial respiratory complex I inhibitor with an IC₅₀ of 2.4 µM for C. elegans complex I. NPD8790 is more selective for nematode species mitochondria than human, bovine, and mouse mitochondria. NPD8790 is an anthelmintic that kills adult soil-transmitted helminths .

HY-B0217R

Nitazoxanide (Standard)	Parasite Influenza Virus Autophagy	Infection Cancer
Nitazoxanide (Standard) is the analytical standard of Nitazoxanide. This product is intended for research and analytical applications. Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC₅₀ of 2.4 μM . Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .

HY-164052

Antiparasitic agent-23

Parasite Infection

Antiparasitic agent-23 (compound 14) is an anthelmintic and insecticide that inhibits insect or helminth parasitism .

Antiparasitic agent-23	Parasite	Infection
Antiparasitic agent-23 (compound 14) is an anthelmintic and insecticide that inhibits insect or helminth parasitism .

HY-B0263S1

Thiabendazole-13C6 2-(4-Thiazolyl)benzimidazole-¹³C₆	Isotope-Labeled Compounds Mitochondrial Metabolism Parasite	Infection
Thiabendazole- ¹³C₆ is the ¹³C₆ labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.

Cat. No.	Product Name

HY-L082

Antiparasitic Compound library	461 compounds
A parasite is an organism that lives on or in a host organism and gets its food from or at the expense of its host. Parasites of humans include protozoans, helminths, and ecto-parasites (organisms that live on the external surface of a host). They are responsible for many diseases and are transmitted to their hosts most often through the ingestion of contaminated food, water or through the bite of an arthropod (e.g., a fly or tick), which can act as an intermediate host and as a vector. Parasitic diseases of humans are a major global health problem causing significant morbidity and mortality, especially in developing countries. Each year there are hundreds of millions of people infected with disease-causing parasites, particularly in tropical and subtropical regions of the world, resulting in an estimated one million deaths. Therefore, there is a dire need of novel anti-parasitic drugs. MCE has a unique collection of 461 compounds with validated anti-parasitic activity which offer researchers an opportunity to screen novel anti-parasitic targets.

Antiparasitic Compound library

461 compounds

A parasite is an organism that lives on or in a host organism and gets its food from or at the expense of its host. Parasites of humans include protozoans, helminths, and ecto-parasites (organisms that live on the external surface of a host). They are responsible for many diseases and are transmitted to their hosts most often through the ingestion of contaminated food, water or through the bite of an arthropod (e.g., a fly or tick), which can act as an intermediate host and as a vector. Parasitic diseases of humans are a major global health problem causing significant morbidity and mortality, especially in developing countries. Each year there are hundreds of millions of people infected with disease-causing parasites, particularly in tropical and subtropical regions of the world, resulting in an estimated one million deaths. Therefore, there is a dire need of novel anti-parasitic drugs.

MCE has a unique collection of 461 compounds with validated anti-parasitic activity which offer researchers an opportunity to screen novel anti-parasitic targets.

Cat. No.	Product Name	Chemical Structure

HY-B0263S1

Thiabendazole-13C6
Thiabendazole- ¹³C₆ is the ¹³C₆ labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Screening Libraries

Isotope-Labeled Compounds

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