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coupling agent

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

3

Biochemical Assay Reagents

2

Peptides

1

Inhibitory Antibodies

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W105426
    3-(Trimethoxysilyl)propyl methacrylate

    [3-(Methacryloyloxy)propyl]trimethoxysilane

    		 Biochemical Assay Reagents Others
    3-(Trimethoxysilyl)propyl methacrylate ([3-(Methacryloyloxy)propyl]trimethoxysilane) is a silane coupling agent that can be used to modify TiO2 nanoparticles. 3-(Trimethoxysilyl)propyl methacrylate is a biomaterial or organic compound that can be used for life science research .
    3-(Trimethoxysilyl)propyl methacrylate
  • HY-91054
    Triethoxyoctylsilane

    		Others Others
    Triethoxyoctylsilane is a silane coupling agent. Triethoxyoctylsilane can be used in plastics applications .
    Triethoxyoctylsilane
  • HY-46225
    DEX-maleimide

    		Others Inflammation/Immunology
    DEX-maleimide is a coupling agent that can be used to synthesize conjugates containing single-domain antibodies (VHH) conjugated with antigens and anti-inflammatory agents. DEX-maleimide can be used for research on autoimmune diseases .
    DEX-maleimide
  • HY-W004650
    TETA hydrochloride hydrate

    		Biochemical Assay Reagents Others
    TETA hydrochloride hydrate is an effective selective chelating agent for copper (II). TETA hydrochloride hydrate can be used for drug coupling .
    TETA hydrochloride hydrate
  • HY-W101718
    Fmoc-N-(2-Boc-aminoethyl)-Gly-OH

    		Isotope-Labeled Compounds ADC Linker Cancer
    Fmoc-N-(2-Boc-aminoethyl)-Gly-OH is a Fmoc-protected glycine derivative that can be used in antibody agent coupling (ADC) synthesis. ADC consists of antibodies that are linked to ADC cytotoxins via ADC junctions[1].
    Fmoc-N-(2-Boc-aminoethyl)-Gly-OH
  • HY-Y1191
    EEDQ

    EEDQ

    		 Biochemical Assay Reagents Others
    EEDQ is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    EEDQ
  • HY-P99205
    Glembatumumab

    		ADC Antibody Cancer
    Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-agent coupling (ADC) with antitumor activity .
    Glembatumumab
  • HY-133513
    (±)-H3RESCA-TFP

    (±)-H3L28

    		 Others Cancer
    (±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine) .
    (±)-H3RESCA-TFP
  • HY-B0558
    Carbimazole

    		p38 MAPK Neurological Disease Endocrinology
    Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
    Carbimazole
  • HY-B0558R
    Carbimazole (Standard)

    		p38 MAPK Neurological Disease Endocrinology
    Carbimazole (Standard) is the analytical standard of Carbimazole. This product is intended for research and analytical applications. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
    Carbimazole (Standard)
  • HY-147363
    DIBAC-GGFG-NH2CH2-Dxd

    		Drug-Linker Conjugates for ADC Others
    DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin (HY-16560) derivative, is a linker-payload of protein-agent conjugates . Dxd (HY-13631D) can be used as a payload for the antibody-coupling drug ADC (DS-8201a).DIBAC-GGFG-NH2CH2-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DIBAC-GGFG-NH2CH2-Dxd
  • HY-145547
    1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine

    14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine

    		 Liposome Metabolic Disease
    1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .
    1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine

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