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arterial thrombosis

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2299
    Morusinol

    		Others Cardiovascular Disease
    Morusinol is a flavonoid isolated from Morus alba root bark. Morusinol has an antiplatelet activity and  significantly inhibits arterial thrombosis in vivo .
    Morusinol
  • HY-D0199
    Adenosine 5'-diphosphate disodium
    1 Publications Verification

    		 Endogenous Metabolite Cardiovascular Disease
    Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .
    Adenosine 5'-diphosphate disodium
  • HY-122592
    Zifaxaban

    		Factor Xa Cardiovascular Disease
    Zifaxaban is an orally active, competitively and selective Factor Xa (FXa) inhibitor with an IC50 of 11.1 nM for human FXa. Zifaxaban shows >10000-fold greater selectivity than other serine proteases. Zifaxaban can be used for the arterial and venous thrombosis research .
    Zifaxaban
  • HY-10270
    Flovagatran

    TGN 255

    		 Thrombin Cardiovascular Disease
    Flovagatran (TGN 255) is a potent and reversible thrombin inhibitor (Ki: 9 nM). Flovagatran can be used in the research of arterial and venous thrombosis .
    Flovagatran
  • HY-153998
    BT100 sodium

    		Integrin Cardiovascular Disease
    BT100 (sodium), a aptamer, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .
    BT100 sodium
  • HY-153999
    BT200

    		Integrin Cardiovascular Disease
    BT200, a pegylated form of the aptamer BT100, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .
    BT200
  • HY-153999A
    BT200 sodium

    		Integrin Cardiovascular Disease
    BT200 sodium, a pegylated form of the aptamer BT100, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .
    BT200 sodium
  • HY-156501
    BT101 sodium

    		Others Cardiovascular Disease
    BT101 (sodium), a complementary aptamer, has been developed to specifically inhibit BT100 function. BT100, a aptamer, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .
    BT101 sodium
  • HY-15468
    IOX2
    Maximum Cited Publications
    9 Publications Verification

    		 HIF/HIF Prolyl-Hydroxylase Cancer
    IOX2 is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases .
    IOX2
  • HY-15468A
    IOX2 sodium

    		HIF/HIF Prolyl-Hydroxylase Cardiovascular Disease Cancer
    IOX2 sodium is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. IOX2 sodium regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 sodium can be used in the study of thrombotic diseases .
    IOX2 sodium
  • HY-162164
    Neuroprotective agent 3

    		Others Neurological Disease
    Neuroprotective agent 3 (Compound 21a) is an antioxidant that exhibits neuroprotective effects. Neuroprotective agent 3 significantly increases neuronal viability and induces neuroprotection, as well as improves neurological deficit scores in an in vivo model of transient cerebral ischemia .
    Neuroprotective agent 3
  • HY-108658
    MRS2500 tetraammonium

    		P2Y Receptor Cardiovascular Disease
    MRS2500 tetraammonium is a potent, selective and stable antagonist of the P2Y1 receptor (Ki=0.78 nM for recombinant human P2Y1 receptor). MRS2500 tetraammonium inhibits the ADP-induced aggregation of human platelets with an IC50 value of 0.95 nM. Antithrombotic activity .
    MRS2500 tetraammonium

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