PG | MedChemExpress (MCE) Life Science Reagents

By Targets:	Apoptosis (7) Autophagy (1) Bacterial (6) Biochemical Assay Reagents (2) CFTR (1) COX (7) DNA/RNA Synthesis (4) Dopamine Receptor (1) Endogenous Metabolite (8) ERK (1) Fluorescent Dye (4) HIF/HIF Prolyl-Hydroxylase (1) Integrin (2) Isotope-Labeled Compounds (15) JAK (2) Ligands for E3 Ligase (1) Liposome (6) Melanocortin Receptor (4) MMP (1) NF-κB (2) P-glycoprotein (1) PGE synthase (1) PPAR (1) Prostaglandin Receptor (9) PROTACs (1) Reactive Oxygen Species (2) SGLT (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (24) Cardiovascular Disease (8) Endocrinology (8) Infection (7) Inflammation/Immunology (21) Metabolic Disease (8) Neurological Disease (2)
Click Chemistry:	Alkynes (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16395

PG-11047

CGC-11047
Others Cancer

PG-11047 (CGC-11047) is a polyamine analogue. PG-11047 can be used for the research of breast cancer .

PG-11047 CGC-11047	Others	Cancer
PG-11047 (CGC-11047) is a polyamine analogue. PG-11047 can be used for the research of breast cancer .

HY-P1208

PG-931	Melanocortin Receptor	Inflammation/Immunology
PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC₅₀=0.58 nM) agonist and is more selective than for the hMC3R (IC₅₀=55 nM) or the hMC5R (IC₅₀=2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo .

HY-16394

PG-11047 tetrahydrochloride CGC-11047 tetrahydrochloride	Others	Cancer
PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities .

HY-103369

PG01	CFTR	Endocrinology
PG01 is a potent CFTR Cl ^- channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K, G970R and G551D (CFTR mutants) with K_d values of 0.22 μM, 0.45 μM and 1.94 μM, respectively. PG01 is also effective on ΔF508 (K_a of 0.3 μM). PG01 increases ΔF508-CFTR Cl ^- current after adding Forskolin .

HY-14240

PG 116800 PG 530742; PGE 530742; PGE 7113313	MMP	Inflammation/Immunology
PG 116800 (PG 530742) is an orally avtive MMP inhibitor. PG 116800 has high affinity for MMP-2, -3, -8, -9, -13, and -14, while having substantially lower affinity for MMP-1 and -7. PG 116800 can be used for knee osteoarthritis research .

HY-P1208A

PG-931 TFA	Melanocortin Receptor	Inflammation/Immunology
PG-931 TFA, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC₅₀=0.58 nM) agonist and is more selective than for the hMC3R (IC₅₀=55 nM) or the hMC5R(IC₅₀=2.4 nM). PG-931 TFA can reverse haemorrhagic shock and prevent multiple organ damage in vivo .

HY-103408

PG01037 dihydrochloride

Dopamine Receptor Neurological Disease

PG01037 (dihydrochloride) is a potent and selective dopamine D3 receptor antagonist with a K_i of 0.7 nM .
HY-148113

PG 34

Others Others

PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor (IC₅₀=68 μM), and a close structural analog of OSMI-1 (HY-119738) .

PG01037 dihydrochloride	Dopamine Receptor	Neurological Disease
PG01037 (dihydrochloride) is a potent and selective dopamine D3 receptor antagonist with a K_i of 0.7 nM .

PG 34	Others	Others
PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor (IC₅₀=68 μM), and a close structural analog of OSMI-1 (HY-119738) .

HY-101277

Vadadustat 5 Publications Verification PG-1016548; AKB-6548	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease
Vadadustat (PG-1016548) is a titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor . Vadadustat is an erythropoiesis-stimulating agent and has the potential for anemia treatment in chronic kidney disease in vivo .

HY-P1209

PG106	Melanocortin Receptor	Inflammation/Immunology
PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC₅₀=210 nM) and has noactivity at hMC4 receptors (EC₅₀=9900 nM) and hMC5 receptor .

HY-P1209A

PG106 TFA	Melanocortin Receptor	Metabolic Disease
PG106 TFA is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC₅₀= 210 nM) and has noactivity at hMC4 receptors (EC₅₀=9900 nM) and hMC5 receptor .

HY-32736

Triptonide 2 Publications Verification NSC 165677; PG 492	Wnt β-catenin Apoptosis Autophagy	Inflammation/Immunology Cancer
Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC₅₀ of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects .

HY-32735

Triptolide Maximum Cited Publications 39 Publications Verification PG490	NF-κB Apoptosis	Cancer
Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor .

HY-148791

Pumecitinib

PG-011
JAK Inflammation/Immunology Cancer

Pumecitinib is a Janus kinase (JAK) inhibitor with anti-inflammatory activity .

Pumecitinib PG-011	JAK	Inflammation/Immunology Cancer
Pumecitinib is a Janus kinase (JAK) inhibitor with anti-inflammatory activity .

HY-107101

(5R)-5-Hydroxytriptolide PG 701; LLDT-8; 5α-Hydroxytriptolide	Others	Inflammation/Immunology
(5R)-5-Hydroxytriptolide is an extracted compound from Tripterygium, and shows lower cell cytotoxicity and higher immunosuppressive activity. (5R)-5-Hydroxytriptolide can be used for study of rheumatoid arthritis .

HY-101988

Prostaglandin D2 PGD2	Prostaglandin Receptor Endogenous Metabolite	Inflammation/Immunology
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals . Prostaglandin D2 is one of the most potent endogenous sleep promoting substances . PGD2 plays a protective role by suppressing inflammation .

HY-32735S

Triptolide-d3 PG490-d₃	Isotope-Labeled Compounds NF-κB Apoptosis	Cancer
Triptolide-d₃ is the deuterium labeled Triptolide. Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor[1][2][3][4][5][6].

HY-P2822

Phosphoglycerate kinase, yeast PGK	Endogenous Metabolite	Infection Endocrinology Cancer
Phosphoglycerate kinase, yeast (PGK), namely phosphoglycerate kinase, is a glycolytic enzyme commonly used in biochemical research. Phosphoglycerate kinase can catalyze the reversible transfer of phosphate groups from 1,3-bisphosphoglycerate (1,3-BPG) to ADP to generate 3-phosphoglycerate (3-PG) and ATP. At the same time, it can also participate in gluconeogenesis, catalyzing the opposite reaction to produce 1,3BPGA and ADP. Phosphoglycerate kinase is involved in energy metabolism, interaction with nucleic acid, tumor progression, cell death and virus replication and other related processes .

HY-145507

1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium) 1-Palmitoyl-2-hydroxy-sn-glycero-3-PG sodium; 16:0 Lyso PG; PG(16:0/0:0); 1-Hexadecanoyl-sn-glycero-3-phospho-(1'racglycerol) (sodium)	Liposome	Metabolic Disease
1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.

HY-162447

P-gp inhibitor 22	P-glycoprotein Apoptosis	Cancer
P-gp inhibitor 22 is a P-glycoprotein (P-gp) inhibitor that effectively inhibits P-pg and efflux function. P-gp inhibitor 22 induces apoptosis and accumulation of MCF-7/ADR cells processed in the S phase .

HY-130463

POPG sodium salt PG(16:0/18:1); 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)	Liposome	Others
POPG sodium salt is a phospholipid molecule having one negative charge, which can interact with the positive charges of peptides .

HY-146854S

15:0 Lyso PG-d5

Isotope-Labeled Compounds Others

15:0 Lyso PG-d₅ is deuterium labeled 15:0 Lyso PG.
HY-146855S

19:0 Lyso PG-d5

Isotope-Labeled Compounds Others

19:0 Lyso PG-d₅ is deuterium labeled 19:0 Lyso PG.
HY-146856S

17:0 Lyso PG-d5

Isotope-Labeled Compounds Others

17:0 Lyso PG-d₅ is deuterium labeled 17:0 Lyso PG.

15:0 Lyso PG-d5	Isotope-Labeled Compounds	Others
15:0 Lyso PG-d₅ is deuterium labeled 15:0 Lyso PG.

19:0 Lyso PG-d5	Isotope-Labeled Compounds	Others
19:0 Lyso PG-d₅ is deuterium labeled 19:0 Lyso PG.

17:0 Lyso PG-d5	Isotope-Labeled Compounds	Others
17:0 Lyso PG-d₅ is deuterium labeled 17:0 Lyso PG.

HY-Y1903

Phosal 50 PG 3 Publications Verification	Biochemical Assay Reagents	Others
Phosal 50 PG is a cosolvent (standardised phosphatidylcholine concentrate). Phosal 50 PG as a carrier for lipophilic compounds, can improve the absorption, efficacy and therapeutic index of the active ingredient .

HY-146853S

17:0-14:1 PG-d5

Isotope-Labeled Compounds Others

17:0-14:1 PG-d₅ is deuterium labeled 17:0-14:1 PG.
HY-146857S

17:0-22:4 PG-d5

Isotope-Labeled Compounds Others

17:0-22:4 PG-d₅ is deuterium labeled 17:0-22:4 PG.
HY-146858S

17:0-20:3 PG-d5

Isotope-Labeled Compounds Others

17:0-20:3 PG-d₅ is deuterium labeled 17:0-20:3 PG.
HY-146859S

17:0-18:1 PG-d5

Isotope-Labeled Compounds Others

17:0-18:1 PG-d₅ is deuterium labeled 17:0-18:1 PG.
HY-146860S

17:0-16:1 PG-d5

Isotope-Labeled Compounds Others

17:0-16:1 PG-d₅ is deuterium labeled 17:0-16:1 PG.
HY-146877S

16:0-18:1 PG-d31

Isotope-Labeled Compounds Others

16:0-18:1 PG-d₃₁ is deuterium labeled 16:0-18:1 PG.
HY-146878S

16:0-18:1 PG-d5

Isotope-Labeled Compounds Others

16:0-18:1 PG-d₅ is deuterium labeled 16:0-18:1 PG.

17:0-14:1 PG-d5	Isotope-Labeled Compounds	Others
17:0-14:1 PG-d₅ is deuterium labeled 17:0-14:1 PG.

17:0-22:4 PG-d5	Isotope-Labeled Compounds	Others
17:0-22:4 PG-d₅ is deuterium labeled 17:0-22:4 PG.

17:0-20:3 PG-d5	Isotope-Labeled Compounds	Others
17:0-20:3 PG-d₅ is deuterium labeled 17:0-20:3 PG.

17:0-18:1 PG-d5	Isotope-Labeled Compounds	Others
17:0-18:1 PG-d₅ is deuterium labeled 17:0-18:1 PG.

17:0-16:1 PG-d5	Isotope-Labeled Compounds	Others
17:0-16:1 PG-d₅ is deuterium labeled 17:0-16:1 PG.

16:0-18:1 PG-d31	Isotope-Labeled Compounds	Others
16:0-18:1 PG-d₃₁ is deuterium labeled 16:0-18:1 PG.

16:0-18:1 PG-d5	Isotope-Labeled Compounds	Others
16:0-18:1 PG-d₅ is deuterium labeled 16:0-18:1 PG.

HY-W339838

1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium 14:0 Lyso PG	Liposome	Cancer
1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium (14:0 Lyso PG) is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .

HY-118414

20-Ethyl prostaglandin E2	Prostaglandin Receptor	Neurological Disease Cancer
20-Ethyl prostaglandin E2 (compound 62) is a PG analog that stimulates Nurr1-dependent transcriptional activity .

HY-153113

Rongliflozin DJT1116PG	SGLT	Endocrinology
Rongliflozin (DJT1116PG) is a selective and orally active inhibitor of sodium-glucose co-transporter-2 (SGLT-2). Rongliflozin can be used for the research of type 2 diabetes mellitus (T2DM) .

HY-118895

L-641953	Prostaglandin Receptor	Cardiovascular Disease
L-641953 is an orally active, selective TXA/PG-END receptor (thromboxane-prostaglandin endoperoxide receptor) antagonist. L-641953 significantly inhibits arachidonic acid-induced bronchoconstriction. L-641953 may be used in cardiovascular disease research .

HY-145505

1-Oleoyl-2-hydroxy-sn-glycero-3-PG sodium 18:1 Lyso-PG; 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol); 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoglycerol	Endogenous Metabolite Liposome	Metabolic Disease
1-Oleoyl-2-hydroxy-sn-glycero-3-PG (18:1 Lyso PE) sodium is a lysophospholipid containing oleic acid (18:1) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.

HY-P1068A

Recombinant human lysozyme (plant expression)	Bacterial	Infection
Recombinant human lysozyme (plant expression) is a conserved anti-bacterial protein that causes bacterial lysis and death by hydrolyzing bacterial cell wall peptidoglycan (PG). Recombinant human lysozyme (plant expression) can be used to study bacterial infections .

HY-124581

DS-6930	PPAR	Metabolic Disease
DS-6930 is a potent and selective agonist of PPARγ, with an EC₅₀ of 41 nM. DS-6930 could robust reduce plasma glucose (PG), and with fewer PPARγ-related adverse effects than Rosiglitazone. DS-6930 can be used for the research of diabetes .

HY-16363

Omtriptolide

ERK Inflammation/Immunology

Omtriptolide (PG490-88) is a derivative proagent of triptolide purified from the Chinese herb.
HY-101602

Aligeron

Prostaglandin Receptor Cardiovascular Disease Endocrinology

Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.
HY-N3079

Phlorin

Phloroglucinol β-D-glucoside
Others Others

Phlorin (Phloroglucinol β-D-glucoside) is a phloroglucinol (PG) glucoside .

Omtriptolide	ERK	Inflammation/Immunology
Omtriptolide (PG490-88) is a derivative proagent of triptolide purified from the Chinese herb.

Aligeron	Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.

Phlorin Phloroglucinol β-D-glucoside	Others	Others
Phlorin (Phloroglucinol β-D-glucoside) is a phloroglucinol (PG) glucoside .

HY-125940

DPPG sodium	Liposome	Others
DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, liposomes and other types of artificial membranes .

HY-163169

Phenyl-glutarimide 4'-oxyacetic acid	Ligands for E3 Ligase	Others
Phenyl-glutarimide 4 ’-oxyacetic acid is a carboxylic acid-functionalized cerebellar ligand that can be used in the development of PROTAC deactivators. Phenyl-glutarimide 4 ’-oxyacetic acid binds to PROTAC has better hydrolytic stability and efficacy .

HY-125940S

DPPG-d62 sodium	Isotope-Labeled Compounds	Others
DPPG-d₆₂ (sodium) is deuterium labeled DPPG. DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, l

HY-145696

SJ10542	PROTACs JAK	Inflammation/Immunology Cancer
SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC₅₀s of 14, 11, and 24 nM for JAK2, JAK3, and JAK2-fusion ALL, respectively. SJ10542 utilizes a PG ligand as the cereblon (CRBN) recruiter .

HY-113756A

Latanoprost acid 1 Publications Verification	Prostaglandin Receptor	Inflammation/Immunology
Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor . Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes .

HY-W251428

Phosphatidylglycerols (egg) (sodium salt) Egg PG	Biochemical Assay Reagents	Others
Phosphatidylglycerol is a naturally occurring anionic phospholipid that is a component of plant, animal and bacterial cell membranes. It is present in prokaryotes and eukaryotes less than phosphatidylethanolamine, and in eukaryotes less than phosphatidylcholine. It is formed by the reaction between CDP-diglyceride and L-α-glycerol 3-phosphate followed by dephosphorylation and is the metabolic precursor of cardiolipin. Phosphatidylglycerols containing polyunsaturated and monounsaturated fatty acyl chains inhibit and promote the proliferation of murine keratinocytes, respectively. Phosphatidylglycerol is the second-largest lipid component of mammalian lung surfactant, accounting for 10% of lipids, and has reduced levels of pulmonary surfactant in infants with respiratory distress syndrome. Phosphatidylglycerol (egg) is a mixture of phosphatidylglycerols isolated from eggs with various fatty acyl groups at the sn-1 and sn-2 positions. References: [1]. Ohtsuka, T., Nishijima, M., and Akamatsu, Y. Phosphatidylglycerol phosphate synthase-deficient somatic mutants with impaired phosphatidylglycerol and cardiolipin biosynthesis J. Biol. Chemical. 268(30), 22908-22913 (1993).[2]. Furse, S. Are phosphatidylglycerols essential for terrestrial life J. Chemistry. biology. 10(1), 1-9 (2016).[3]. Xie, D., Seremwe, M., Edwards, JG, et al. Different effects of different phosphatidylglycerols on the proliferation of mouse keratinocytes PLoS One 9(9), e107119 (2014).

HY-147097

EDA-DA	Bacterial	Infection
EDA-DA, a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. Peptidoglycan (PG), an essential structure in the cell walls of the vast majority of bacteria, is critical for division and maintaining cell shape and hydrostatic pressure . EDA-DA is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-121825

U-44069

Others Cardiovascular Disease

U-44069 is a stable prostaglandin (PG) H2 analogue and a potent vasoconstrictor. U-44069 induces Ca influx at preglomerular vessels .

Cat. No.	Product Name	Type

HY-131045

HADA hydrochloride 2 Publications Verification HCC-Amino-D-alanine hydrochloride	Dyes
HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λ_em~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation .

HY-12591

D-Luciferin sodium

Maximum Cited Publications

38 Publications Verification

D-(-)-Luciferin sodium; Firefly luciferin sodium; Beetle Luciferin sodium

Chromogenic Substrates

D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .

HY-12591A

D-Luciferin

Maximum Cited Publications

38 Publications Verification

D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin

Chromogenic Substrates

D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .

HY-12591B

D-Luciferin potassium

Maximum Cited Publications

38 Publications Verification

D-(-)-Luciferin potassium; Firefly luciferin potassium; Beetle Luciferin potassium

Chromogenic Substrates

D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We offer the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .

HY-D0153

Tetramethylrhodamine-5-isothiocyanate	Fluorescent Dyes/Probes
Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles .

Cat. No.	Product Name	Type

HY-Y1903

Phosal 50 PG 3 Publications Verification	Co-solvents
Phosal 50 PG is a cosolvent (standardised phosphatidylcholine concentrate). Phosal 50 PG as a carrier for lipophilic compounds, can improve the absorption, efficacy and therapeutic index of the active ingredient .

HY-125940

DPPG sodium	Drug Delivery
DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, liposomes and other types of artificial membranes .

HY-W251428

Phosphatidylglycerols (egg) (sodium salt)

Egg PG

Biochemical Assay Reagents

Phosphatidylglycerol is a naturally occurring anionic phospholipid that is a component of plant, animal and bacterial cell membranes. It is present in prokaryotes and eukaryotes less than phosphatidylethanolamine, and in eukaryotes less than phosphatidylcholine. It is formed by the reaction between CDP-diglyceride and L-α-glycerol 3-phosphate followed by dephosphorylation and is the metabolic precursor of cardiolipin. Phosphatidylglycerols containing polyunsaturated and monounsaturated fatty acyl chains inhibit and promote the proliferation of murine keratinocytes, respectively. Phosphatidylglycerol is the second-largest lipid component of mammalian lung surfactant, accounting for 10% of lipids, and has reduced levels of pulmonary surfactant in infants with respiratory distress syndrome. Phosphatidylglycerol (egg) is a mixture of phosphatidylglycerols isolated from eggs with various fatty acyl groups at the sn-1 and sn-2 positions. References: [1]. Ohtsuka, T., Nishijima, M., and Akamatsu, Y. Phosphatidylglycerol phosphate synthase-deficient somatic mutants with impaired phosphatidylglycerol and cardiolipin biosynthesis J. Biol. Chemical. 268(30), 22908-22913 (1993).[2]. Furse, S. Are phosphatidylglycerols essential for terrestrial life J. Chemistry. biology. 10(1), 1-9 (2016).[3]. Xie, D., Seremwe, M., Edwards, JG, et al. Different effects of different phosphatidylglycerols on the proliferation of mouse keratinocytes PLoS One 9(9), e107119 (2014).

HY-145974A

m7GpppAmpG ammonium m7G(5')ppp(5')(2'OMeA)PG ammonium	Gene Sequencing and Synthesis
m7GpppAmpG ammonium is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 90% .

HY-145973A

3'OMe-m7GpppAmpG ammonium m7(3'OMeG)(5')ppp(5')(2'OMeA)PG ammonium	Gene Sequencing and Synthesis
3'OMe-m7GpppAmpG ammonium is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG ammonium shows a significant translational efficiency. 3'OMe-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .

Cat. No.	Product Name	Target	Research Area

HY-P1208

PG-931	Melanocortin Receptor	Inflammation/Immunology
PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC₅₀=0.58 nM) agonist and is more selective than for the hMC3R (IC₅₀=55 nM) or the hMC5R (IC₅₀=2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo .

HY-P1209A

PG106 TFA	Melanocortin Receptor	Metabolic Disease
PG106 TFA is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC₅₀= 210 nM) and has noactivity at hMC4 receptors (EC₅₀=9900 nM) and hMC5 receptor .

HY-P1208A

PG-931 TFA	Melanocortin Receptor	Inflammation/Immunology
PG-931 TFA, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC₅₀=0.58 nM) agonist and is more selective than for the hMC3R (IC₅₀=55 nM) or the hMC5R(IC₅₀=2.4 nM). PG-931 TFA can reverse haemorrhagic shock and prevent multiple organ damage in vivo .

HY-P1209

PG106	Melanocortin Receptor	Inflammation/Immunology
PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC₅₀=210 nM) and has noactivity at hMC4 receptors (EC₅₀=9900 nM) and hMC5 receptor .

HY-P1633

Protegrin-1

PG1
Peptides Others

Protegrin-1 is a antimicrobial peptide with antimicrobial activity
HY-P1187

HSDVHK-NH2

Integrin Cancer

HSDVHK-NH2 is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC₅₀ of 1.74 pg/mL (2.414 pM) .
HY-P1187A

HSDVHK-NH2 TFA

Integrin Cancer

HSDVHK-NH2 TFA is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC₅₀ of 1.74 pg/mL (2.414 pM) .

Cat. No.	Product Name	Target	Research Area

HY-P99978A

Mouse IgG2a (LALA-PG), Isotype Control	Inhibitory Antibodies	Others
Mouse IgG2a (LALA-PG), Isotype Control is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse IgG2a.

HY-P990182

Mouse IgG2b (LALA-PG) kappa, isotype control	Inhibitory Antibodies	Others
Mouse IgG2b (LALA-PG) kappa, isotype control is a mouse-derived IgG2b, κ type antibody inhibitor, targeting to mouse IgG2b.

HY-P990240

Anti-Mouse GITR (LALA-PG) Antibody (DTA-1-CP029)	Inhibitory Antibodies	Others
Anti-Mouse GITR (LALA-PG) Antibody (DTA-1-CP029) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse GITR.

HY-P99123A

Anti-Mouse CD28 (LALA-PG) Antibody (D665-CP043)	Inhibitory Antibodies	Others
Anti-Mouse CD28 (LALA-PG) Antibody (D665-CP043) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD28.

HY-P990234

Anti-Mouse ICOSL/CD275 (LALA-PG) Antibody (HK5.3-CP046)	Inhibitory Antibodies	Others
Anti-Mouse ICOSL/CD275 (LALA-PG) Antibody (HK5.3-CP046) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse ICOSL/CD275.

HY-P990176

Anti-Mouse OX40/CD134 (LALA-PG) Antibody (OX86-CP018)	Inhibitory Antibodies	Others
Anti-Mouse OX40/CD134 (LALA-PG) Antibody (OX86-CP018) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse OX40/CD134.

HY-P990269

Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1-CP034)	Inhibitory Antibodies	Others
Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1-CP034) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD40L/CD154.

HY-P990256

Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9-CP008)	Inhibitory Antibodies	Others
Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9-CP008) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse CTLA-4/CD152.

HY-P99119A

Anti-Mouse 4-1BB/CD137 (LALA-PG) Antibody (LOB12.3-CP038)	Inhibitory Antibodies	Others
Anti-Mouse 4-1BB/CD137 (LALA-PG) Antibody (LOB12.3-CP038) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse 4-1BB/CD137.

HY-P990290

Anti-Mouse CD16/CD32 (LALA-PG) Antibody (2.4G2-CP026)	Inhibitory Antibodies	Others
Anti-Mouse CD16/CD32 (LALA-PG) Antibody (2.4G2-CP026) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD16/CD32.

HY-P990171

Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2?-CP154)	Inhibitory Antibodies	Others
Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2?-CP154) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse PD-L1/B7-H1.

HY-P990304C

Anti-Mouse 4-1BBL/CD137L (LALA-PG) Antibody (TKS-1-CP041)

Inhibitory Antibodies Others

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-32736

Triptonide 2 Publications Verification NSC 165677; PG 492	Classification of Application Fields Terpenoids Source classification Celastraceae Diterpenoids Plants Tripterygium wilfordii Hook. f. Disease Research Fields Inflammation/Immunology	Wnt β-catenin Apoptosis Autophagy
Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC₅₀ of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects .

HY-32735

Triptolide Maximum Cited Publications 39 Publications Verification PG490	Structural Classification Classification of Application Fields Anti-aging Source classification Celastraceae Tripterygium wilfordii Hook. f. Plants Biological Pesticide Research Agricultural Research Terpenoids Diterpenoids Disease Research Fields Cancer	NF-κB Apoptosis
Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor .

HY-101988

Prostaglandin D2 PGD2	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	Prostaglandin Receptor Endogenous Metabolite
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals . Prostaglandin D2 is one of the most potent endogenous sleep promoting substances . PGD2 plays a protective role by suppressing inflammation .

HY-N3079

Phlorin Phloroglucinol β-D-glucoside	Structural Classification Urginea Steinh. Source classification Phenols Polyphenols Plants Saccharides Monosaccharides Asparagaceae Juss.	Others
Phlorin (Phloroglucinol β-D-glucoside) is a phloroglucinol (PG) glucoside .

HY-116015

Dihomo-γ-Linolenic acid methyl ester	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Dihomo-γ-Linolenic acid is an n-6 polyunsaturated fatty acid that is mainly metabolized to an anti-inflammatory eicosanoid, prostaglandin (PG) E1, via the cyclooxygenase (COX) pathway. Anti-inflammatory and anti-proliferative effects .

HY-113505

Delta-12-Prostaglandin J2 Δ12-PGJ2	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation .

HY-101193

Zinc Protoporphyrin 30+ Cited Publications Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Cancer	Reactive Oxygen Species Endogenous Metabolite Apoptosis
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H₂O₂ . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

HY-12591A

D-Luciferin 35+ Cited Publications D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin	Natural Products Animals Source classification Other Diseases Disease Research Fields	Fluorescent Dye
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .

Species:	Human (7) Rat (1) Mouse (2) Cynomolgus (1)
Tag:	His (10) Myc (2) Fc (1) B2M (1)
Source:	HEK293 (10) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P74202

	Decorin/PGS2 Protein, Rat (HEK293, His) 1 Publications Verification Decorin; Bone proteoglycan II; PG-S2; PG40; DCN; SLRR1B	Rat	HEK293
	Decorin/PGS2 protein is involved in regulating extracellular matrix dynamics, affecting the rate of fibril formation and participating in rat cervical dilation. It has versatile binding properties, interacting with type I and type II collagen, fibronectin, and TGF-β, suggesting involvement in a variety of cellular processes. Decorin/PGS2 Protein, Rat (HEK293, His) is the recombinant rat-derived Decorin/PGS2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P70021

	Decorin/PGS2 Protein, Mouse (HEK293, His) rMuDecorin/PGS2, His; Decorin; Bone proteoglycan II; PG-S2; PG40; Dcn	Mouse	HEK293
	Decorin/PGS2 protein, influencing fibril formation rate, binds strongly to type I and type II collagen, fibronectin, and TGF-beta. It participates in extracellular matrix organization by forming a ternary complex with MFAP2 and ELN, and interacts with DPT, potentially modulating matrix assembly and structure. Decorin/PGS2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Decorin/PGS2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Decorin/PGS2 Protein, Mouse (HEK293, His) is 338 a.a., with molecular weight of 41-50 kDa.

HY-P7885

	Decorin/PGS2 Protein, Human (HEK293, His) rHuDecorin/PGS2, His; Decorin; Bone proteoglycan II; PG-S2; PG40; DCN; SLRR1B	Human	HEK293
	Decorin/PGS2 Protein, Human (HEK 293, His) expresses in HEK293 with a His tag at the N-terminus. Decorin, an extracellular matrix (ECM) protein, belongs to the small leucine-rich proteoglycan family. Decorin acts as a ligand of various cytokines and growth factors by directly or indirectly interacting with the corresponding signalling molecules involved in cell growth, differentiation, proliferation, adhesion and metastasis.

HY-P77914

	DLK-1 Protein, Human (HEK293, His) PG2; FA1; DLK; DLK1; DLK-1; Pref1; secredeltin; ZOG	Human	HEK293
	The DLK-1 protein has been implicated in neuroendocrine differentiation, suggesting a role in the complex processes that control neuroendocrine cell development and specialization. As a monomer, the single molecular form of DLK-1 helps carry out its biological activity. DLK-1 Protein, Human (HEK293, His) is the recombinant human-derived DLK-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of DLK-1 Protein, Human (HEK293, His) is 280 a.a., with molecular weight of 40-50 kDa.

HY-P77915

	DLK-1 Protein, Mouse (HEK293, His) PG2; FA1; DLK; DLK1; DLK-1; Pref1; secredeltin; ZOG	Mouse	HEK293
	DLK-1 Protein is implicated in neuroendocrine differentiation, signifying its role in cellular specialization. It acts as an inhibitor of adipocyte differentiation, regulating adipogenesis. Structurally, DLK-1 exists as a monomer, defining its molecular composition in these processes. Interactions with SH3RF2 underscore its engagement with cellular components and potential regulatory pathways. DLK-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DLK-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of DLK-1 Protein, Mouse (HEK293, His) is 282 a.a., with molecular weight of 50-68 kDa.

HY-P700706

	DLK-1 Protein, Cynomolgus (HEK293, His) PG2; FA1; DLK; DLK1; DLK-1; Pref1; secredeltin; ZOG	Cynomolgus	HEK293
	DLK-1, also known as pre adipokine, is a transmembrane-secreted protein with an epidermal growth factor (EGF) -like repeat sequence. DLK-1 regulates the growth of pioneer axons by controlling Wnt signaling. DLK-1 is a cell surface protein expressed in many cancers, including hepatocellular carcinoma, and maybe a potential target for monoclonal antibodies to treat cancer. DLK-1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived DLK-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of DLK-1 Protein, Cynomolgus (HEK293, His) is 283 a.a., with molecular weight of 42-52 kDa.

HY-P700856

	DLK-1 Protein, Human (HEK293, hFc) PG2; FA1; DLK; DLK1; DLK-1; Pref1; secredeltin; ZOG	Human	HEK293
	The DLK-1 protein has been implicated in neuroendocrine differentiation, suggesting a role in the complex processes that control neuroendocrine cell development and specialization. As a monomer, the single molecular form of DLK-1 helps carry out its biological activity. DLK-1 Protein, Human (HEK293, hFc) is the recombinant human-derived DLK-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of DLK-1 Protein, Human (HEK293, hFc) is 280 a.a., with molecular weight of 70-80 kDa.

HY-P70138

	DLK-1 Protein, Human (S260N, HEK293, His) rHuDelta-like 1 homolog/DLK-1, His; Protein Delta Homolog 1; DLK-1; PG2; DLK1; DLK	Human	HEK293
	DLK-1 Protein is implicated in neuroendocrine differentiation, signifying its role in cellular specialization. It acts as an inhibitor of adipocyte differentiation, regulating adipogenesis. Structurally, DLK-1 exists as a monomer, defining its molecular composition in these processes. Interactions with SH3RF2 underscore its engagement with cellular components and potential regulatory pathways. DLK-1 Protein, Human (S260N, HEK293, His) is the recombinant human-derived DLK-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of DLK-1 Protein, Human (S260N, HEK293, His) is 274 a.a., with molecular weight of 35-45 kDa.

HY-P702616

	Versican Isoform V0 Protein, Human (His, B2M, Myc) Versican core protein; VCAN; Chondroitin sulfate proteoglycan core protein 2; Chondroitin sulfate proteoglycan 2; Glial hyaluronate-binding protein; GHAP; Large fibroblast proteoglycan; PG-M; CSPG2	Human	E. coli

HY-P76059

Serglycin/SRGN Protein, Human (HEK293, His)

Hematopoietic proteoglycan core protein; Platelet proteoglycan core protein; P.PG; SRGN; PRG; PRG1
Human HEK293

HY-P76058

	Serglycin/SRGN Protein, Human (HEK293, His-Myc) Hematopoietic proteoglycan core protein; Platelet proteoglycan core protein; P.PG; SRGN; PRG; PRG1	Human	HEK293
	Serine (SRGN) is essential for the formation of mast cell secretory granules and the storage of various compounds. It plays a crucial role in the storage of proteases in mast cells, including granzyme B in T lymphocytes, and contributes to the localization of neutrophil elastase. Serglycin/SRGN Protein, Human (HEK293, His-Myc) is the recombinant human-derived Serglycin/SRGN protein, expressed by HEK293 , with C-His, C-Myc labeled tag.

Cat. No.	Product Name	Chemical Structure

HY-32735S

Triptolide-d3
Triptolide-d₃ is the deuterium labeled Triptolide. Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor[1][2][3][4][5][6].

HY-146854S

15:0 Lyso PG-d5

15:0 Lyso PG-d₅ is deuterium labeled 15:0 Lyso PG.
HY-146855S

19:0 Lyso PG-d5

19:0 Lyso PG-d₅ is deuterium labeled 19:0 Lyso PG.
HY-146856S

17:0 Lyso PG-d5

17:0 Lyso PG-d₅ is deuterium labeled 17:0 Lyso PG.
HY-146853S

17:0-14:1 PG-d5

17:0-14:1 PG-d₅ is deuterium labeled 17:0-14:1 PG.
HY-146857S

17:0-22:4 PG-d5

17:0-22:4 PG-d₅ is deuterium labeled 17:0-22:4 PG.
HY-146858S

17:0-20:3 PG-d5

17:0-20:3 PG-d₅ is deuterium labeled 17:0-20:3 PG.
HY-146859S

17:0-18:1 PG-d5

17:0-18:1 PG-d₅ is deuterium labeled 17:0-18:1 PG.
HY-146860S

17:0-16:1 PG-d5

17:0-16:1 PG-d₅ is deuterium labeled 17:0-16:1 PG.
HY-146877S

16:0-18:1 PG-d31

16:0-18:1 PG-d₃₁ is deuterium labeled 16:0-18:1 PG.
HY-146878S

16:0-18:1 PG-d5

16:0-18:1 PG-d₅ is deuterium labeled 16:0-18:1 PG.

HY-125940S

DPPG-d62 sodium
DPPG-d₆₂ (sodium) is deuterium labeled DPPG. DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, l

HY-17474S

Parecoxib-d3

Parecoxib-d3 is the deuterium labeled Parecoxib. Parecoxib (SC 69124) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo.

HY-17474AS

Parecoxib-d5 sodium

Parecoxib-d5 (sodium) is the deuterium labeled Parecoxib sodium. Parecoxib Sodium (SC 69124A) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib Sodium can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo[1][2].

HY-101193S

Zinc Protoporphyrin-d2,15N2

Zinc Protoporphyrin-d₂, ¹⁵N₂ is ¹⁵N and deuterated labeled Zinc Protoporphyrin (HY-101193). Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H₂O₂ . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82562

	Biglycan Antibody (YA2307) BGN; Biglycan; DSPG1; PG S1; PGI; SEMDX; SLRR1A	WB, IP, FC	Human, Mouse, Rat
	Biglycan Antibody (YA2307) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2307), targeting Biglycan, with a predicted molecular weight of 42 kDa (observed band size: 42 kDa). Biglycan Antibody (YA2307) can be used for WB, IP, FC experiment in human, mouse, rat background.

HY-P80772

	P Glycoprotein Antibody p-PG; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243	WB	Human
	P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.

Cat. No.	Product Name		Classification

HY-147097A

EDA-DA TFA		Alkynes
EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-147097

EDA-DA		Alkynes
EDA-DA, a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. Peptidoglycan (PG), an essential structure in the cell walls of the vast majority of bacteria, is critical for division and maintaining cell shape and hydrostatic pressure . EDA-DA is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.


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PG

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

PG

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Natural
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