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Tomaralimab (OPN-305) is a humanised anti-TLR2 IgG4 monoclonal antibody. Tomaralimab has the potential for the research of Myelodysplastic Syndromes (MDS) .
OPN expression inhibitor 1 (Compound 11) is an osteopontin (OPN) expression inhibitor. OPN expression inhibitor 1 can be used for breast cancer research .
OPN3 Human Pre-designed siRNA Set A contains three designed siRNAs for OPN3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
OPN4 Human Pre-designed siRNA Set A contains three designed siRNAs for OPN4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
OPN5 Human Pre-designed siRNA Set A contains three designed siRNAs for OPN5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
OPN1LW Human Pre-designed siRNA Set A contains three designed siRNAs for OPN1LW gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
OPN1MW Human Pre-designed siRNA Set A contains three designed siRNAs for OPN1MW gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
OPN1SW Human Pre-designed siRNA Set A contains three designed siRNAs for OPN1SW gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).
5-Aminosalicylic acid-d3 disodium is deuterated labeled 5-Aminosalicylic Acid (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).
N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring α-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer can promote abnormal O-glycosylation of CD44, thereby activating the Wnt/β-catenin signaling pathway and regulating the malignant behavior of gastric cancer cells. Additionally, N-Acetylgalactosaminyltransferase 1 plays a crucial role in cancer growth and metastasis by modifying the O-glycosylation of various glycoproteins, such as mucin (MUC1), osteopontin (OPN), matrix metalloproteinase-14 (MMP14), and integrin α3 .
Tomaralimab (OPN-305) is a humanised anti-TLR2 IgG4 monoclonal antibody. Tomaralimab has the potential for the research of Myelodysplastic Syndromes (MDS) .
5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).
Osteopontin/OPN Protein, a vital member of the osteopontin family, plays a pivotal role in cell adhesion, immune response modulation, and tissue mineralization. Sharing conserved features within the family, Osteopontin's versatile nature contributes to both homeostatic and pathological conditions. Its study provides valuable insights into the broader understanding of the osteopontin family's roles in biological functions, offering potential therapeutic avenues and further exploration of intricate interactions within cellular pathways. Osteopontin/OPN Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Osteopontin/OPN protein, expressed by HEK293, with C-His labeled tag. The total length of Osteopontin/OPN Protein, Cynomolgus (HEK293, His) is 284 a.a., with molecular weight of 45-55 kDa.
Osteopontin/OPN Protein, a crucial non-collagenous bone protein, binds strongly to hydroxyapatite, integral to the mineralized matrix. It likely plays a vital role in mediating cell-extracellular matrix interactions. Moreover, as a cytokine, OPN efficiently induces interferon-gamma and interleukin-12 production while inhibiting interleukin-10, pivotal in promoting type I immunity. Osteopontin/OPN Protein, Mouse (HEK293, His) is the recombinant mouse-derived Osteopontin/OPN protein, expressed by HEK293 , with C-His labeled tag. The total length of Osteopontin/OPN Protein, Mouse (HEK293, His) is 278 a.a., with molecular weight of 50-60 kDa.
Osteopontin/OPN Protein, a key non-collagenous bone protein, strongly binds to hydroxyapatite, contributing to the mineralized matrix. Its significant role in cell-matrix interactions is evident. Acting as a cytokine, OPN promotes interferon-gamma and interleukin-12 production while suppressing interleukin-10, crucial for type I immunity. Osteopontin/OPN Protein, Human (HEK293, His) is the recombinant human-derived Osteopontin/OPN protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Osteopontin/OPN Protein, Human (HEK293, His) is 298 a.a., with molecular weight of 50-65 kDa.
OPN1LW protein, crucial for vision, is a vital element of visual pigments responsible for light absorption. The pigments consist of opsin, forming a covalent bond with cis-retinal. This molecular mechanism is indispensable for perceiving light stimuli in vision. OPN1LW Protein, Human (Cell-Free, His) is the recombinant human-derived OPN1LW protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of OPN1LW Protein, Human (Cell-Free, His) is 364 a.a., with molecular weight of 43.4 kDa.
Osteopontin/OPN Protein, a crucial non-collagenous bone protein, binds strongly to hydroxyapatite, integral to the mineralized matrix. It likely plays a vital role in mediating cell-extracellular matrix interactions. Moreover, as a cytokine, OPN efficiently induces interferon-gamma and interleukin-12 production while inhibiting interleukin-10, pivotal in promoting type I immunity. Osteopontin/OPN Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Osteopontin/OPN protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Osteopontin/OPN Protein, Mouse (P.pastoris, His) is 274 a.a., with molecular weight (glycosylation form) of ~60 kDa.
Osteopontin/OPN Protein, a key non-collagenous bone protein, strongly binds to hydroxyapatite, crucial for the mineralized matrix. It likely plays a vital role in mediating cell-extracellular matrix interactions. Additionally, as a cytokine, OPN stimulates interferon-gamma and interleukin-12 production, while inhibiting interleukin-10, pivotal for the type I immunity pathway. Osteopontin/OPN Protein, Rat (CHO, His) is the recombinant rat-derived Osteopontin/OPN protein, expressed by CHO , with C-6*His labeled tag. The total length of Osteopontin/OPN Protein, Rat (CHO, His) is 301 a.a., with molecular weight of approximately 34.83 kDa.
5-Aminosalicylic acid-d3 disodium is deuterated labeled 5-Aminosalicylic Acid (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).
SPP1; BNSP; OPN; PSEC0156; Osteopontin; Bone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; Uropontin
WB, IHC-P, ELISA
Human, Mouse, Rat
Osteopontin Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 35 kDa, targeting to Osteopontin. It can be used for WB,IHC-P,ELISA assays with tag free, in the background of Human, Mouse, Rat.
Rhodopsin Antibody (YA3269) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3269), targeting Rhodopsin, with a predicted molecular weight of 39 kDa (observed band size: 39 kDa). Rhodopsin Antibody (YA3269) can be used for WB, IHC-P experiment in human, rat background.
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