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MSTO-211H cell-derived xenograft (CDX) models

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-158384
    IAG933

    		YAP Cancer
    IAG933 is a small molecule compound. IAG933 is a direct and selective disruptor of YAP-TEAD protein-protein interaction (PPI). By binding to the Ω-loop pocket of TEAD protein, IAG933 directly prevents YAP/TAZ from forming complexes with TEADs, thereby interfering with YAP's carcinogenic function. IAG933 can be used to study the Hippo signaling pathway and specific types of cancer .
    IAG933

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