F7 | MedChemExpress (MCE) Life Science Reagents

By Targets:	ADC Cytotoxin (1) ADC Linker (2) Apoptosis (1) Endogenous Metabolite (3) HPV (1) Isotope-Labeled Compounds (1) Small Interfering RNA (siRNA) (2) Survivin (1) Topoisomerase (1) Wnt (1)
By Research Areas:	Cancer (6) Metabolic Disease (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-156095

F7H	Wnt	Cancer
F7H is a Frizzled receptor FZD7 antagonist (IC₅₀: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD) .

HY-113437A

1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite . It is used in the generation of micelles, liposomes, and artificial membranes.

HY-113437AS

1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d₆₂ (sodium) is deuterium labeled 1,2-Dipalmitoyl-sn-glycerol 3-phosphate. 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite[1].

HY-RS04645

F7 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
F7 Human Pre-designed siRNA Set A contains three designed siRNAs for F7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

F7 Human Pre-designed siRNA Set A F7 Human Pre-designed siRNA Set A

HY-113437

1,2-Dipalmitoyl-sn-glycerol 3-phosphate	Endogenous Metabolite	Metabolic Disease
1,2-Dipalmitoyl-sn-glycerol 3-phosphate (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite .

HY-RS04116

E2F7 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
E2F7 Human Pre-designed siRNA Set A contains three designed siRNAs for E2F7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

E2F7 Human Pre-designed siRNA Set A E2F7 Human Pre-designed siRNA Set A

HY-122678

LQZ-7F	Survivin Apoptosis	Cancer
LQZ-7F, a survivin dimerization inhibitor, induces spontaneous apoptosis and synergizes with Docetaxel in prostate cancer cells. LQZ-7F dose-dependently inhibits survival of both PC-3 and C4-2 cells with IC₅₀s of 2.99 and 2.47 µM, respectively .

HY-148696A

Gly-Cyclopropane-Exatecan	ADC Cytotoxin Topoisomerase	Cancer
Gly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan (HY-13631), a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro .

HY-46572

Benzyl 2-cyclopropyl-2-hydroxyacetate	ADC Linker	Cancer
Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate in the synthesis of ADC linker.The linker composed of Benzyl 2-cyclopropyl-2-hydroxyacetate can be coupled to Exatecan (HY-13631) and combined with antibodies (such as antibody hu2F7) .

HY-W250541

Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH	ADC Linker	Cancer
Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH is an intermediate in the synthesis of ADC linker.The linker composed of Benzyl 2-cyclopropyl-2-hydroxyacetate can be coupled to Exatecan (HY-13631) and combined with antibodies (such as antibody hu2F7) .

HY-146033

HPV18-IN-1	HPV	Cancer
HPV18-IN-1 (Compound H1) is a potent inhibitor of HPV18. HPV18-IN-1 prevents cervical cancer cells from premature cell procession and abnormal proliferation. HPV18-IN-1 supresses E7-Rb-E2F cellular pathway and DNA methylation. HPV18-IN-1 has the potential for the research of cancer diseases .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113437A

1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite . It is used in the generation of micelles, liposomes, and artificial membranes.

HY-113437

1,2-Dipalmitoyl-sn-glycerol 3-phosphate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1,2-Dipalmitoyl-sn-glycerol 3-phosphate (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite .

Species:	Human (7) Mouse (1)
Tag:	SUMO (1) His (6) Tag Free (2)
Source:	HEK293 (3) CHO (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P74239

	Coagulation Factor VII/F7 Protein, Human (HEK293, His) Coagulation factor VII; Eptacog alfa; F7; FVII coagulation protein; SPCA	Human	HEK293
	Coagulation factor VII (F7) initiates the extrinsic pathway of blood coagulation. As a circulating zymogen, F7 is activated to F7a through proteolysis induced by factor Xa, factor XIIa, factor IXa, or thrombin. In the presence of tissue factor and calcium ions, F7a catalyzes limited proteolysis of factor X, converting it to factor Xa. F7a can also convert factor IX to factor IXa, emphasizing its pivotal role in coagulation cascades. Coagulation Factor VII/F7 Protein, Human (HEK293, His) is the recombinant human-derived Coagulation Factor VII/F7 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor VII/F7 Protein, Human (HEK293, His) is 406 a.a., with molecular weight of ~50 kDa.

HY-P73045

	Coagulation Factor VII/F7 Protein, Mouse (CHO, His) Coagulation factor VII; Eptacog alfa; F7; FVII coagulation protein; SPCA	Mouse	CHO
	Coagulation Factor VII (F7) protein lacks crucial conserved residue(s) needed for propagating feature annotation. Coagulation Factor VII/F7 Protein, Mouse (CHO, His) is the recombinant mouse-derived Coagulation Factor VII/F7 protein, expressed by CHO , with C-His labeled tag. The total length of Coagulation Factor VII/F7 Protein, Mouse (CHO, His) is 422 a.a., with molecular weight of 56-63 kDa.

HY-P701289

	FITC-Labeled Basigin/CD147 Protein, Human (HEK293, His) Basigin; BSG; 5F7; CD147; EMMPRIN; M6; OK; TCSF	Human	HEK293
	Basigin/BSG proteins are critical for retinal maturation and development and function as retinal cell receptors for NXNL1, promoting the survival of retinal cone photoreceptors. FITC-Labeled Basigin/CD147 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled Basigin/CD147 protein, expressed by HEK293 , with His labeled tag. The total length of FITC-Labeled Basigin/CD147 Protein, Human (HEK293, His) is 184 a.a., with molecular weight of 28-40 kDa.

HY-P73879

	IL-37 Protein, Human (166a.a) Interleukin-37; IL-37; FIL1 zeta; IL-1X; IL-1F7; IL1H4	Human	E. coli
	IL-37 Protein, a crucial immune regulatory cytokine, suppresses innate inflammatory and immune responses, mitigating excessive inflammation. It signals intracellularly via nuclear translocation with SMAD3 and extracellularly by binding to its receptor, composed of IL18R1 and IL18RAP. IL-37 inhibits pro-inflammatory cytokines, sparing anti-inflammatory ones, and hinders dendritic cell activation. It interacts with SMAD3, binds IL18R1 (with lower affinity than IL18), and forms a complex with TMED10 for secretion. IL-37 Protein, Human (166a.a) is the recombinant human-derived IL-37 protein, expressed by E. coli , with tag free. The total length of IL-37 Protein, Human (166a.a) is 166 a.a., with molecular weight of ~18.7 kDa.

HY-P700565

	Coagulation factor VII/F7 Protein, Human (His-SUMO) Coagulation factor VII; Eptacog alfa; F7; FVII coagulation protein; SPCA	Human	E. coli
	Coagulation factor VII (F7) initiates the extrinsic pathway of blood coagulation. As a circulating zymogen, F7 is activated to F7a through proteolysis induced by factor Xa, factor XIIa, factor IXa, or thrombin. In the presence of tissue factor and calcium ions, F7a catalyzes limited proteolysis of factor X, converting it to factor Xa. F7a can also convert factor IX to factor IXa, emphasizing its pivotal role in coagulation cascades. Coagulation factor VII/F7 Protein, Human (His-SUMO) is the recombinant human-derived Coagulation factor VII/F7 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of Coagulation factor VII/F7 Protein, Human (His-SUMO) is 152 a.a., with molecular weight of 33 kDa.

HY-P70455

	IL-37 Protein, Human 1 Publications Verification Interleukin-37; FIL1 Zeta; IL-1X; Interleukin-1 Family Member 7; IL-1F7; Interleukin-1 Homolog 4; IL-1H; IL-1H4; Interleukin-1 Zeta; IL-1 Zeta; Interleukin-1-Related Protein; IL-1RP1; Interleukin-23; IL-37; IL37; FIL1Z; IL1F7; IL1H4; IL1RP1	Human	E. coli
	IL-37 protein is an important immunoregulatory cytokine that suppresses innate inflammation and immune responses and reduces excessive inflammation. It signals intracellularly through nuclear translocation of SMAD3 and extracellularly through binding to its receptors, consisting of IL18R1 and IL18RAP. IL-37 Protein, Human is the recombinant human-derived IL-37 protein, expressed by E. coli , with tag free. The total length of IL-37 Protein, Human is 166 a.a., with molecular weight of ~18-20 kDa.

HY-P700128AF

	Animal-Free IL-37 Protein, Human (His) Interleukin-37; FIL1 Zeta; IL-1X; Interleukin-1 Family Member 7; IL-1F7; Interleukin-1 Homolog 4; IL-1H; IL-1H4; Interleukin-1 Zeta; IL-1 Zeta; Interleukin-1-Related Protein; IL-1RP1; Interleukin-23; IL-37; IL37; FIL1Z; IL1F7; IL1H4; IL1RP1	Human	E. coli
	IL-37 protein is an important immunoregulatory cytokine that suppresses innate inflammation and immune responses and reduces excessive inflammation. It signals intracellularly through nuclear translocation of SMAD3 and extracellularly through binding to its receptors, consisting of IL18R1 and IL18RAP. Animal-Free IL-37 Protein, Human (His) is the recombinant human-derived animal-FreeIL-37 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-37 Protein, Human (His) is 166 a.a., with molecular weight of ~19.49 kDa.

HY-P70029

	Basigin/CD147 Protein, Human (HEK293, His) rHuBasigin/CD147, His ; Basigin; 5F7; Collagenase Stimulatory Factor; Extracellular Matrix Metalloproteinase Inducer; EMMPRIN; Leukocyte Activation Antigen M6; OK Blood Group Antigen; Tumor Cell-Derived Collagenase Stimulatory Factor; TCSF; CD147; BSG	Human	HEK293
	Basigin/BSG proteins are critical for retinal maturation and development and function as retinal cell receptors for NXNL1, promoting the survival of retinal cone photoreceptors. Basigin/CD147 Protein, Human (HEK293, His) is the recombinant human-derived Basigin/CD147 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Basigin/CD147 Protein, Human (HEK293, His) is 184 a.a., with molecular weight of 30-40 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-113437AS

1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium
1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d₆₂ (sodium) is deuterium labeled 1,2-Dipalmitoyl-sn-glycerol 3-phosphate. 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite[1].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83689

	CD147 Antibody (YA3422) HT-7; CD147; EMMPRIN; AI115436; AI325119; BSG; Basigin; 5F7; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD antigen CD147	WB, IHC-P, IHC-F, ICC/IF	Human
	CD147 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 42 kDa, targeting to CD147. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human.

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F7

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F7

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