2. MAPK/ERK Pathway NF-κB
  3. p38 MAPK NF-κB
  4. Salixteroside D

Salixteroside D is a salicin derivative, that exhibits anti-inflammatory activity through inhibition of MAPK and NF-κB signaling pathways.

For research use only. We do not sell to patients.

Salixteroside D Chemical Structure

Salixteroside D Chemical Structure

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Salixteroside D Related Antibodies

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Description

Salixteroside D is a salicin derivative, that exhibits anti-inflammatory activity through inhibition of MAPK and NF-κB signaling pathways[1].

In Vitro

Salixteroside D (20 μM, 24 h) inhibits NO production in RAW 264.7 with an IC50 of 6.75 μM, without cytotoxicity in cell RAW 264.7[1].
Salixteroside D (5-20 μM, 12 h) inhibits the expressions of inflammatory mediators IL-1β, IL-6, iNOS and COX-2 in Lipopolysaccharides (HY-D1056)-induced RAW 264.7 macrophages[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Salixteroside D Related Antibodies

Western Blot Analysis[1]

Cell Line: RAW 264.7
Concentration: 5-20 μM
Incubation Time: 12 h
Result: Decreased mRNA levels of iNOS and COX-2.
Molecular Weight

466.44

Formula

C22H26O11
SMILES

CC(OC1[C@H]([C@@H](O[C@@H]([C@H]1O)CO)OC2=CC=CC=C2COC([C@@]3(C=CCCC3=O)O)=O)O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Salixteroside D Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Salixteroside Dp38 MAPKNF-κBNuclear factor-κBNuclear factor-kappaBRAW 264.7macrophagesalicinInhibitorinhibitorinhibit

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Salixteroside D
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HY-N12767
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