S-Adenosyl-L-methionine iodide (Synonyms: S-Adenosyl methionine iodide; Ademetionine iodide; AdoMet iodide)

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S-(5'-Adenosyl)-L-methionine iodide (S-Adenosyl-L-methionine iodide) is an important methyl donor that is found in all living organisms.

For research use only. We do not sell to patients.

S-Adenosyl-L-methionine iodide Chemical Structure

CAS No. : 3493-13-8

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Other In-stock Forms of S-Adenosyl-L-methionine iodide:

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8 Publications Citing Use of MCE S-Adenosyl-L-methionine iodide

: S-Adenosyl-L-methionine iodide purchased from MedChemExpress. Usage Cited in: Int Immunopharmacol. 2021 Mar 22;95:107545. [Abstract]; S-adenosylmethionine (SAMe) application at 30 min prior to high glucose treatment significantly increased H2S levels compared with the HG group. The cystathionine-β-synthase (CBS) level is obviously elevated in HG + SAMe group compared with the HG group.

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Description

S-(5'-Adenosyl)-L-methionine iodide (S-Adenosyl-L-methionine iodide) is an important methyl donor that is found in all living organisms^[1].

IC₅₀ & Target

Human Endogenous Metabolite

In Vitro

By donating the methyl group, sues that involves perchloric acid extraction has been SAM is converted into S-adenosyl-L-homocysteine reported by She et al. Separation of SAM and (SAH)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

526.35

Formula

C₁₅H₂₃IN₆O₅S

CAS No.

3493-13-8

SMILES

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1C[S+](CC[C@H](N)C(O)=O)C.[I-]

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. W Wang, et al. Reversed-phase high-performance liquid chromatography procedure for the simultaneous determination of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine in mouse liver and the effect of methionine on their concentrations. J Chromatogr B Biomed Sci Appl. 2001 Oct 5;762(1):59-65. [Content Brief]

S-Adenosyl-L-methionine iodide Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S-Adenosyl-L-methionine3493-13-8S-Adenosyl methionineAdemetionineAdoMetEndogenous MetaboliteInhibitorinhibitorinhibit

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