2. Metabolic Enzyme/Protease Apoptosis
  3. Endogenous Metabolite Apoptosis
  4. Prostaglandin A2

Prostaglandin A2 (PGA2), a human endogenous metabolite of PGE2, is an antitumor agent. Prostaglandin A2 induces p53-dependent apoptosis. Prostaglandin A2 also has antiviral activity.

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Prostaglandin A2 Chemical Structure

Prostaglandin A2 Chemical Structure

CAS No. : 13345-50-1

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Other Forms of Prostaglandin A2:

Prostaglandin A2 Related Antibodies

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Description

Prostaglandin A2 (PGA2), a human endogenous metabolite of PGE2, is an antitumor agent. Prostaglandin A2 induces p53-dependent apoptosis. Prostaglandin A2 also has antiviral activity[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

334.45

Formula

C20H30O4
CAS No.
Appearance

Oil

Color

White to light brown

SMILES

CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C=C1)=O)C/C=C\CCCC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (149.50 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9900 mL 14.9499 mL 29.8998 mL
5 mM 0.5980 mL 2.9900 mL 5.9800 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9900 mL 14.9499 mL 29.8998 mL 74.7496 mL
5 mM 0.5980 mL 2.9900 mL 5.9800 mL 14.9499 mL
10 mM 0.2990 mL 1.4950 mL 2.9900 mL 7.4750 mL
15 mM 0.1993 mL 0.9967 mL 1.9933 mL 4.9833 mL
20 mM 0.1495 mL 0.7475 mL 1.4950 mL 3.7375 mL
25 mM 0.1196 mL 0.5980 mL 1.1960 mL 2.9900 mL
30 mM 0.0997 mL 0.4983 mL 0.9967 mL 2.4917 mL
40 mM 0.0747 mL 0.3737 mL 0.7475 mL 1.8687 mL
50 mM 0.0598 mL 0.2990 mL 0.5980 mL 1.4950 mL
60 mM 0.0498 mL 0.2492 mL 0.4983 mL 1.2458 mL
80 mM 0.0374 mL 0.1869 mL 0.3737 mL 0.9344 mL
100 mM 0.0299 mL 0.1495 mL 0.2990 mL 0.7475 mL
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Prostaglandin A2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Prostaglandin A213345-50-1PGA2 MedullinProstaglandin A 2Prostaglandin A-2PGA 2PGA-2Endogenous MetaboliteApoptosisPGE2antitumorp53antiviralInhibitorinhibitorinhibit

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