2. Immunology/Inflammation
  3. PSMA
  4. Piflufolastat

Piflufolastat  (Synonyms: DCFPYL)

Cat. No.: HY-117756 Purity: 99.10%
COA Handling Instructions

Molarity Calculator

Piflufolastat (DCFPYL) can be used to the preparation of piflufolastat F 18 (DCFPyL F-18). piflufolastat F 18. Piflufolastat F-18 is an 18F-labelled diagnostic imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) that targets prostate-specific membrane antigen (PSMA).

For research use only. We do not sell to patients.

Piflufolastat Chemical Structure

Piflufolastat Chemical Structure

CAS No. : 1423758-00-2

Size Price Stock Quantity
5 mg USD 150 In-stock
10 mg USD 250 In-stock
25 mg USD 550 In-stock
50 mg USD 950 In-stock
100 mg USD 1650 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Piflufolastat Related Antibodies

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Description

Piflufolastat (DCFPYL) can be used to the preparation of piflufolastat F 18 (DCFPyL F-18). piflufolastat F 18. Piflufolastat F-18 is an 18F-labelled diagnostic imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) that targets prostate-specific membrane antigen (PSMA)[1].

Clinical Trial
Molecular Weight

442.40

Formula

C18H23FN4O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CC[C@H](NC(N[C@@H](CCCCNC(C1=CC=C(N=C1)F)=O)C(O)=O)=O)C(O)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 175 mg/mL (395.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2604 mL 11.3020 mL 22.6040 mL
5 mM 0.4521 mL 2.2604 mL 4.5208 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2604 mL 11.3020 mL 22.6040 mL 56.5099 mL
5 mM 0.4521 mL 2.2604 mL 4.5208 mL 11.3020 mL
10 mM 0.2260 mL 1.1302 mL 2.2604 mL 5.6510 mL
15 mM 0.1507 mL 0.7535 mL 1.5069 mL 3.7673 mL
20 mM 0.1130 mL 0.5651 mL 1.1302 mL 2.8255 mL
25 mM 0.0904 mL 0.4521 mL 0.9042 mL 2.2604 mL
30 mM 0.0753 mL 0.3767 mL 0.7535 mL 1.8837 mL
40 mM 0.0565 mL 0.2825 mL 0.5651 mL 1.4127 mL
50 mM 0.0452 mL 0.2260 mL 0.4521 mL 1.1302 mL
60 mM 0.0377 mL 0.1884 mL 0.3767 mL 0.9418 mL
80 mM 0.0283 mL 0.1413 mL 0.2825 mL 0.7064 mL
100 mM 0.0226 mL 0.1130 mL 0.2260 mL 0.5651 mL
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Piflufolastat Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Piflufolastat1423758-00-2DCFPYLPSMAProstate-specific membrane antigenDiagnosticpositronemissiontomographyPETInhibitorinhibitorinhibit

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