2. Peptides
  3. Peptide and Derivatives
  4. Peptides for Drug Delivery
  5. Cell-penetrating Peptides

Cell-penetrating Peptides

Cell-penetrating Peptides (91):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P4108
    TAT-HA2 Fusion Peptide 923954-79-4 99.93%
    TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide induces the cellular uptake of macromolecules into endosomes via the TAT moiety and to respond to the acidifying lumen of endosomes to cause membrane leakage and release of macromolecules into cells via the HA2 moiety.
    TAT-HA2 Fusion Peptide
  • HY-P0311A
    LAH4 TFA 99.17%
    LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes.
    LAH4 TFA
  • HY-P1876B
    NLS (PKKKRKV) (hydrochloride) 99.60%
    NLS (PKKKRKV) hydrochloride is the hydrochloride form of NLS (PKKKRKV) (HY-P1876). NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen), that mediates binding of the karyophilic protein to importin α. NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research.
    NLS (PKKKRKV) (hydrochloride)
  • HY-P1848
    Pep-1 (uncapped) 395069-86-0 99.96%
    Pep-1 (uncapped) is a cell-penetrating peptide.
    Pep-1 (uncapped)
  • HY-P2529
    Penetratin 940866-75-1 99.95%
    Penetratin is a peptide derived from the amphiphilic Drosophila Antennapedia homeodomain.
    Penetratin
  • HY-P1351
    Angiopep-2-Cys 906480-09-9 99.94%
    Angiopep-2-cys is a conjugate of Angiopep-2 hydrochloride (HY-P2341) and cysteine. Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer.
    Angiopep-2-Cys
  • HY-P0282A
    TAT peptide TFA 99.49%
    TAT peptide (TFA) is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1.
    TAT peptide TFA
  • HY-P1491
    HIV-1 TAT (48-60) 220408-24-2 99.80%
    HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way.
    HIV-1 TAT (48-60)
  • HY-P0281A
    TAT TFA 98.40%
    TAT TFA (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins.
    TAT TFA
  • HY-P0133B
    (Arg)9 acetate 99.89%
    (Arg)9 (Nona-L-arginine) acetate is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 acetate has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.
    (Arg)9 acetate
  • HY-P1575
    TAT (48-57) 253141-50-3 98.65%
    TAT (48-57) is a cell-permeable peptide, derived from HIV-1 transactivator of transcription (Tat) protein residue 48-57.
    TAT (48-57)
  • HY-P2193
    TAT-amide 697226-52-1 99.72%
    TAT-amide is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells.
    TAT-amide
  • HY-P0307A
    Antennapedia Peptide TFA 98.84%
    Antennapedia Peptide (Penetratin peptide) TFA is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.
    Antennapedia Peptide TFA
  • HY-P0310
    SV40 large T antigen NLS 163815-24-5 98.98%
    SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus.
    SV40 large T antigen NLS
  • HY-P4086
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) 1678417-57-6 98.00%
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R), a chimeric peptide consisting of 29 amino acids, is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein). Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) is positively charged and able to bind negatively charged nucleic acids via charge interaction.
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R)
  • HY-P4093
    Cys-Penetratin 209323-98-8 99.94%
    Cys-Penetratin is a cell-penetrating peptide (CPP) with sequence of CRQIKIWFQNRRMKWKK.
    Cys-Penetratin
  • HY-P0285A
    Rabies Virus Glycoprotein TFA 98.32%
    Rabies Virus Glycoprotein (TFA) is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells.
    Rabies Virus Glycoprotein TFA
  • HY-P5284
    RALA peptide 1613231-49-4 99.69%
    RALA peptide is a cell-penetrating peptide. RALA peptide can be as non-viral gene delivery vectors.
    RALA peptide
  • HY-P5623B
    RVG TFA 98.25%
    RVG TFA is a peptide derived from Rabies Virus Glycoprotein that binds to the α-7 subunit of nicotinic acetylcholine receptors (AchR) of neuronal cells. RVG enhances delivery of Mycobacterium tuberculosis antigens to antigen-presenting cells.
    RVG TFA
  • HY-P5307
    Peptide A5K
    Peptide A5K (INF7-A5K-TAT) is an RNP delivery peptide that delivers CRISPR RNPs to T cells. Peptide A5K effectively edits T cells without substantial impact on T cell viability.
    Peptide A5K