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  5. Pentigetide

Pentigetide is a sythsis pepetide (Asp-Ser-Asp-Pro-Arg or D-S-D-P-R), also know as “HEPP” for “Human IgE Pentapeptide”. Pentigetide can not produce IgE inhibition in several different systems, due to the aspartic acids in HEPP changed into an asparagine.

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Pentigetide Chemical Structure

Pentigetide Chemical Structure

CAS No. : 62087-72-3

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Based on 1 publication(s) in Google Scholar

Pentigetide Related Antibodies

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Description

Pentigetide is a sythsis pepetide (Asp-Ser-Asp-Pro-Arg or D-S-D-P-R), also know as “HEPP” for “Human IgE Pentapeptide”. Pentigetide can not produce IgE inhibition in several different systems, due to the aspartic acids in HEPP changed into an asparagine[1].

Molecular Weight

588.57

Formula

C22H36N8O11
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

DSDPR
SMILES

OC(C[C@H](N)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N1[C@@H](CCC1)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (84.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6990 mL 8.4952 mL 16.9903 mL
5 mM 0.3398 mL 1.6990 mL 3.3981 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6990 mL 8.4952 mL 16.9903 mL 42.4758 mL
5 mM 0.3398 mL 1.6990 mL 3.3981 mL 8.4952 mL
10 mM 0.1699 mL 0.8495 mL 1.6990 mL 4.2476 mL
15 mM 0.1133 mL 0.5663 mL 1.1327 mL 2.8317 mL
20 mM 0.0850 mL 0.4248 mL 0.8495 mL 2.1238 mL
25 mM 0.0680 mL 0.3398 mL 0.6796 mL 1.6990 mL
30 mM 0.0566 mL 0.2832 mL 0.5663 mL 1.4159 mL
40 mM 0.0425 mL 0.2124 mL 0.4248 mL 1.0619 mL
50 mM 0.0340 mL 0.1699 mL 0.3398 mL 0.8495 mL
60 mM 0.0283 mL 0.1416 mL 0.2832 mL 0.7079 mL
80 mM 0.0212 mL 0.1062 mL 0.2124 mL 0.5309 mL
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Pentigetide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pentigetide62087-72-3OthersIgEpentapeptidetoxicolInhibitorinhibitorinhibit

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