Linoleic acid-d₄

Cat. No.: HY-N0729S Purity: 98.10%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Linoleic Acid-d₄ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

For research use only. We do not sell to patients.

Linoleic acid-d<sub>4</sub> Chemical Structure

Linoleic acid-d₄ Chemical Structure

CAS No. : 79050-23-0

Size	Price	Stock	Quantity
Solvent
500μg（17.58 mM * 99.98 μL in Methyl acetate）	USD 210	In-stock	Estimated Time of Arrival: December 31

Synthetic products have potential research and development risk.

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Linoleic acid-d₄:

Linoleic acid In-stock
Linoleic acid-d₁₁ Get quote

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description	Linoleic Acid-d₄ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Linoleic acid-d₄ Related Antibodies
Molecular Weight	284.47
Formula	C₁₈H₂₈D₄O₂
CAS No.	79050-23-0
Unlabeled CAS	60-33-3
Appearance	Liquid
Color	Colorless to light yellow
SMILES	CCCCC/C([2H])=C(C/C([2H])=C(CCCCCCCC(O)=O)/[2H])/[2H]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Solution, -20°C, 2 years
Solvent & Solubility	In Vitro: DMSO : 100 mg/mL (351.53 mM; from Oleic Acid; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Ethanol : 100 mg/mL (351.53 mM; from Oleic Acid) DMF : 100 mg/mL (351.53 mM; from Oleic Acid) Ethanol : 100 mg/mL (351.53 mM; from Oleic Acid) DMF : 100 mg/mL (351.53 mM; from Oleic Acid) DMSO : 100 mg/mL (351.53 mM; from Oleic Acid; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) 0.15 M Tris-HCl pH 8.5 : 1 mg/mL (3.52 mM; from Oleic Acid) PBS : 0.1 mg/mL (0.35 mM; from Oleic Acid) Molarity Calculator Dilution Calculator Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight * Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) This equation is commonly abbreviated as: C₁V₁ = C₂V₂ Concentration _(start) C1 × Volume _(start) V1 = Concentration _(final) C2 × Volume _(final) V2 In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL
Purity & Documentation	Purity: 98.10% Select Batch: Data Sheet (269 KB) SDS (251 KB) COA (245 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief] [2]. Jay Whelan. Linoleic Acid. Adv Nutr. 2013 May; 4(3): 311–312. [Content Brief] [3]. Yuan T, et al. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. Int J Clin Exp Pathol. 2015 May 1;8(5):5044-52. [Content Brief]

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

0.15 M Tris-HCl pH 8.5 / DMSO / Ethanol / DMF / Ethanol / DMF / DMSO	1 mM	3.5153 mL	17.5765 mL	35.1531 mL	87.8827 mL
DMSO / Ethanol / DMF / Ethanol / DMF / DMSO	5 mM	0.7031 mL	3.5153 mL	7.0306 mL	17.5765 mL
	10 mM	0.3515 mL	1.7577 mL	3.5153 mL	8.7883 mL
	15 mM	0.2344 mL	1.1718 mL	2.3435 mL	5.8588 mL
	20 mM	0.1758 mL	0.8788 mL	1.7577 mL	4.3941 mL
	25 mM	0.1406 mL	0.7031 mL	1.4061 mL	3.5153 mL
	30 mM	0.1172 mL	0.5859 mL	1.1718 mL	2.9294 mL
	40 mM	0.0879 mL	0.4394 mL	0.8788 mL	2.1971 mL
	50 mM	0.0703 mL	0.3515 mL	0.7031 mL	1.7577 mL
	60 mM	0.0586 mL	0.2929 mL	0.5859 mL	1.4647 mL
	80 mM	0.0439 mL	0.2197 mL	0.4394 mL	1.0985 mL
	100 mM	0.0352 mL	0.1758 mL	0.3515 mL	0.8788 mL