2. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. 5-HT Receptor Drug Metabolite
  4. Ketanserinol

Ketanserinol (R 46742) is a metabolite of Ketanserin (HY-10562). Ketanserinol is a competitive antagonist of the effects of 5-HT (HY-B1473A) in both arteries. The KB values are 6.5 for large coronary arteries and 6.4 for pulmonary arteries.

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Ketanserinol Chemical Structure

Ketanserinol Chemical Structure

CAS No. : 76330-73-9

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Description

Ketanserinol (R 46742) is a metabolite of Ketanserin (HY-10562). Ketanserinol is a competitive antagonist of the effects of 5-HT (HY-B1473A) in both arteries. The KB values are 6.5 for large coronary arteries and 6.4 for pulmonary arteries[1].

Molecular Weight

397.44

Formula

C22H24FN3O3
CAS No.
Appearance

Solid

SMILES

O=C(NC1=C(C2=O)C=CC=C1)N2CCN3CCC(CC3)C(O)C4=CC=C(C=C4)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
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Ketanserinol Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ketanserinol76330-73-9R 46742R46742R-467425-HT ReceptorDrug MetaboliteSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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