Hydrocortisone hemisuccinate hydrate  (Synonyms: Hydrocortisone 21-hemisuccinate hydrate)

Hydrocortisone hemisuccinate hydrate (5,6,7-Trihydroxyflavone hydrate), a physiological glucocorticoid, is an orally active steroidal anti-in ammatory agent (SAID). Hydrocortisone hemisuccinate hydrate inhibits proinflammatory cytokine activity, with IC50s of 6.7 and 21.4 μM for IL-6 and IL-3, respectively. Hydrocortisone hemisuccinate hydrate can be used for the research of ulcerative colitis (UC).

480.55

C₂₅H₃₆O₉

83784-20-7

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Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

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  [2]. You YC, et, al. In vitro and in vivo application of pH-sensitive colon-targeting polysaccharide hydrogel used for ulcerative colitis therapy. Carbohydr Polym. 2015 Oct 5;130:243-53.  [Content Brief]

  [3]. Langhoff E, et, al. The immunosuppressive potency in vitro of physiological and synthetic steroids on lymphocyte cultures. Int J Immunopharmacol. 1987;9(4):469-73.  [Content Brief]