GluR6 antagonist-1

Cat. No.: HY-147132 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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GluR6 antagonist-1 is a benzothiophene derivative, acting as a GluR6 antagonist. GluR6 antagonist-1 can be used for researching acute and chronic neurological disorders.

For research use only. We do not sell to patients.

GluR6 antagonist-1 Chemical Structure

CAS No. : 323176-64-3

Size	Price	Stock	Quantity
5 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 170	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

GluR6 antagonist-1 is a benzothiophene derivative, acting as a GluR6 antagonist. GluR6 antagonist-1 can be used for researching acute and chronic neurological disorders^[1].

IC₅₀ & Target

GluR6^[1]

Molecular Weight

302.78

Formula

C₁₅H₁₁ClN₂OS

CAS No.

323176-64-3

Appearance

Solid

Color

Yellow to brown

SMILES

O=C(C1=C(Cl)C2=C(C=CC=C2)S1)NCC3=CC=CN=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 61 mg/mL (201.47 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3027 mL	16.5136 mL	33.0273 mL
5 mM	0.6605 mL	3.3027 mL	6.6055 mL
10 mM	0.3303 mL	1.6514 mL	3.3027 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (251 KB) HNMR (149 KB)

Handling Instructions (2659 KB)

References

[1]. BAKER STEPHEN RICHARD, et al. BENZOTHIOPHENE DERIVATIVES. WO2001007431 A2 (example 20)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.3027 mL	16.5136 mL	33.0273 mL	82.5682 mL
	5 mM	0.6605 mL	3.3027 mL	6.6055 mL	16.5136 mL
	10 mM	0.3303 mL	1.6514 mL	3.3027 mL	8.2568 mL
	15 mM	0.2202 mL	1.1009 mL	2.2018 mL	5.5045 mL
	20 mM	0.1651 mL	0.8257 mL	1.6514 mL	4.1284 mL
	25 mM	0.1321 mL	0.6605 mL	1.3211 mL	3.3027 mL
	30 mM	0.1101 mL	0.5505 mL	1.1009 mL	2.7523 mL
	40 mM	0.0826 mL	0.4128 mL	0.8257 mL	2.0642 mL
	50 mM	0.0661 mL	0.3303 mL	0.6605 mL	1.6514 mL
	60 mM	0.0550 mL	0.2752 mL	0.5505 mL	1.3761 mL
	80 mM	0.0413 mL	0.2064 mL	0.4128 mL	1.0321 mL
	100 mM	0.0330 mL	0.1651 mL	0.3303 mL	0.8257 mL