2. Gene
  3. TRAF3IP3 - TRAF3 interacting protein 3 Gene

TRAF3IP3 - TRAF3 interacting protein 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as T3JAM

Gene ID: 80342 | Gene type: protein coding

About TRAF3IP3

Cytogenetic location: 1q32.2 Genomic coordinates (GRCh38): 1:209,756,053-209,782,310 (from NCBI)

This gene has 16 transcripts (splice variants), 189 orthologues and 2 paralogues. Biased expression in lymph node (RPKM 18.7), spleen (RPKM 13.0) and 9 other tissues.

Summary

The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the Phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

TRAF3IP3 Products(4)

mRNA Protein Name
NM_001287754.2 NP_001274683.1 TRAF3-interacting JNK-activating modulator isoform 2
NM_001320143.2 NP_001307072.1 TRAF3-interacting JNK-activating modulator isoform 1
NM_001320144.2 NP_001307073.1 TRAF3-interacting JNK-activating modulator isoform 4
NM_025228.4 NP_079504.2 TRAF3-interacting JNK-activating modulator isoform 1
Protein Preferred Names Protein Names

TRAF3-interacting JNK-activating modulator

TRAF3 interacting Jun N terminal kinase (JNK) activating modulator

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14972 TRAF3IP3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TRAF3IP3 VGNC VGNC:36275
Mus musculus TRAF3IP3 MGD MGI:2441706
Rattus norvegicus TRAF3IP3 RGD RGD:1304848
Felis catus TRAF3IP3 VGNC VGNC:66499
Canis familiaris TRAF3IP3 VGNC VGNC:47767
Macaca mulatta TRAF3IP3 VGNC VGNC:79877