2. Gene
  3. XCL1 - X-C motif chemokine ligand 1 Gene

XCL1 - X-C motif chemokine ligand 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a

Gene ID: 6375 | Gene type: protein coding

About XCL1

Cytogenetic location: 1q24.2 Genomic coordinates (GRCh38): 1:168,576,605-168,582,069 (from NCBI)

This gene has 1 transcript (splice variant), 116 orthologues and 25 paralogues. Low expression observed in reference dataset.

Summary

This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014]

XCL1 Products(1)

mRNA Protein Name
NM_002995.3 NP_002986.1 lymphotactin precursor

XCL1 Protein Structure

IL8

IL8: Small cytokines (intecrine/chemokine), interleukin-8 like (29 - 83)

  • 0
  • 100
  • 114 a.a.
Protein Preferred Names Protein Names

lymphotactin

SCM-1-alpha

Recombinant XCL1 Proteins

Cat. No. Product Name Accession Purity
HY-P7234 Lymphotactin/XCL1 Protein, Human P47992 (G23-G114) ≥95%
HY-P71434 Lymphotactin/XCL1 Protein, Human (HEK293, Fc-His) P47992 (V22-G114) ≥95%

Related Diseases

Diseases Alias
Sodoku Disease

Spirillosis

Sodoku

Spirillary Fever

Rat-Bite Fever

Rat-Bite Fever Due To Spirillum Minus

Spirillary Rat-Bite Fever

Sokosho
Renal Tuberculosis

Tuberculosis, Renal

Tuberculosis Of Kidney

Tuberculosis Renal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15866 XCL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus XCL1 RGD RGD:620452
Mus musculus XCL1 MGD MGI:104593
Canis familiaris XCL1 NCBI
Macaca fascicularis XCL1 NCBI
Susscrofa domestica XCL1 NCBI
Macaca mulatta XCL1 NCBI