AQP6 - aquaporin 6 Gene

Homo sapiens

Also known as KID; AQP2L

Gene ID: 363 | Gene type: protein coding

About AQP6

Cytogenetic location: 12q13.12 Genomic coordinates (GRCh38): 12:49,972,947-49,977,139 (from NCBI)

This gene has 5 transcripts (splice variants), 548 orthologues and 11 paralogues. Biased expression in kidney (RPKM 15.5), brain (RPKM 1.4) and 1 other tissue.

Summary

The protein encoded by this gene is an Aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. [provided by RefSeq, Jul 2008]

AQP6 Products(1)

mRNA	Protein	Name
NM_001652.4	NP_001643.2	aquaporin-6

AQP6 Protein Structure

MIP

0
100
200
282 a.a.

Protein Preferred Names

Protein Names

aquaporin-6

AQP-6

Related Diseases

Diseases

Alias

Inner Ear Disease

Labyrinthine Dysfunction	Diseases Of Inner Ear
Labyrinthine Disease	Abnormality Of The Inner Ear
Labyrinth Diseases	Labyrinthine Disorder
Nonfunctioning Labyrinth	Labyrinthine Loss Of Function
Labyrinthine Syndrome	Labyrinthine Disorder Nos

Gestational Diabetes Insipidus

Transient Diabetes Insipidus Of Pregnancy	Diabetes Insipidus Gestational
Gestagenic Diabetes Insipidus	Doid:0081057

Viral Labyrinthitis

Epidemic Vertigo

Vestibular Neuronitis

Nephrogenic Diabetes Insipidus

Vasopressin-Resistant Diabetes Insipidus	Diabetes Insipidus, Nephrogenic
Diabetes Insipidus Nephrogenic	Congenital Nephrogenic Diabetes Insipidus
Adh Resistant Diabetes Insipidus	Diabetes Insipidus Nephrogenic X-Linked
Diabetes Insipidus Nephrogenic Type 1	Adh-Resistant Diabetes Insipidus
Diabetes Insipidus Renalis	Ndi
Renal Diabetes Insipidus	Familial Nephrogenic Diabetes
Antidiuretic-Hormone-Resistant Diabetes Insipidus	Adiuretin-Resistant Diabetes Insipidus
Ndi - [Nephrogenic Diabetes Insipidus]	Diabetes Tenuifluus
Adh - [Antidiuretic-Hormone] Resistant Diabetes Insipidus	Hereditary Nephrogenic Diabetes Insipidus
Familial Nephrogenic Diabetes Insipidus	Primary Nephrogenic Diabetes Insipidus

Pompholyx

Dyshidrosis	Vesicular Eczema Of Hands And/Or Feet
Cheiropompholyx	Dyshydrotic Eczema
Eczema, Dyshidrotic	Vesicular Hand Eczema

Peripheral Vertigo

Vertigo, Peripheral

Renal Oncocytoma

Oncocytoma, Renal	Oncocytoma Of Kidney
Renal Epithelial Oncocytic Tumor	Oncocytoma Kidney
Oncocytoma Renal	Kidney Oncocytoma

Meniere Disease

Meniere'S Disease	Otogenic Vertigo
Ménière Disease	Ménière'S Disease
Mnire'S Vertigo	Auditory Vertigo
Aural Vertigo	Meniere'S Syndrome
Ménière'S Vertigo	Primary Endolymphatic Hydrops
Menieres Disease	Vertigo, Aural
Labyrinth Hydrops	Labyrinthine Hydrops
Labyrinthine Vertigo	Ménière Syndrome
Ménière Vertigo	Idiopathic Endolymphatic Hydrops

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00878	AQP6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	AQP6	RGD	RGD:71100
Bos taurus	AQP6	VGNC	VGNC:26049
Canis familiaris	AQP6	VGNC	VGNC:38019
Macaca mulatta	AQP6	VGNC	VGNC:69994
Mus musculus	AQP6	MGD	MGI:1341204
Felis catus	AQP6	VGNC	VGNC:67972

Name
Email *

	Sorry, but the email address you supplied was invalid.