1. Gene
  2. Ccr8 - C-C motif chemokine receptor 8 Gene

Ccr8 - C-C motif chemokine receptor 8 Gene

Rattus norvegicus
Gene ID: 301066 | Gene type: protein coding

About Ccr8

Primary_assembly 8: 119,826,568-119,827,629 forward strand.mRatBN7.2:CM026981.1

This gene has 1 transcript (splice variant), 236 orthologues, 24 paralogues and is associated with 3 phenotypes.

Summary

Predicted to enable C-C chemokine binding activity and C-C Chemokine Receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within chemotaxis. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Biomarker of asthma and pulmonary fibrosis. Orthologous to human CCR8 (C-C motif Chemokine Receptor 8). [provided by Alliance of Genome Resources, Apr 2022]

Ccr8 Products(1)

mRNA Protein Name
XM_008766702.3 XP_008764924.1 C-C chemokine receptor type 8

Ccr8 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (33 - 308)

7tm_GPCRs

7tm_GPCRs: cd14964 (35 - 59)

7tm_GPCRs

7tm_GPCRs: cd14964 (68 - 89)

7tm_GPCRs

7tm_GPCRs: cd14964 (104 - 126)

7tm_GPCRs

7tm_GPCRs: cd14964 (149 - 165)

7tm_GPCRs

7tm_GPCRs: cd14964 (193 - 216)

7tm_GPCRs

7tm_GPCRs: cd14964 (234 - 256)

7tm_GPCRs

7tm_GPCRs: cd14964 (276 - 301)

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  • 353 a.a.
Protein Preferred Names Protein Names

C-C chemokine receptor type 8

chemokine (C-C motif) receptor 8

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccr8 NCBI NCBI:1237
Macaca fascicularis Ccr8 NCBI NCBI:102132857