GTF2F1 - general transcription factor IIF subunit 1 Gene

Homo sapiens

Also known as BTF4; RAP74; TF2F1; TFIIF

Gene ID: 2962 | Gene type: protein coding

About GTF2F1

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:6,379,572-6,393,164 (from NCBI)

This gene has 6 transcripts (splice variants) and 211 orthologues. Ubiquitous expression in ovary (RPKM 36.8), testis (RPKM 30.9) and 25 other tissues.

Summary

Enables several functions, including RNA polymerase II general transcription initiation factor activity; Phosphatase activator activity; and promoter-specific chromatin binding activity. Involved in several processes, including positive regulation of transcription by RNA polymerase II; response to virus; and transcription initiation from RNA polymerase II promoter. Located in cell junction and nucleoplasm. Part of transcription factor TFIID complex. [provided by Alliance of Genome Resources, Apr 2022]

GTF2F1 Products(1)

mRNA	Protein	Name
NM_002096.3	NP_002087.2	general transcription factor IIF subunit 1

GTF2F1 Protein Structure

TFIIF_alpha

0
100
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300
400
517 a.a.

Protein Preferred Names

Protein Names

general transcription factor IIF subunit 1

TFIIF-alpha

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05896	GTF2F1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	GTF2F1	RGD	RGD:1359646
Bos taurus	GTF2F1	VGNC	VGNC:97277
Canis familiaris	GTF2F1	VGNC	VGNC:41546
Macaca mulatta	GTF2F1	VGNC	VGNC:73309
Felis catus	GTF2F1	VGNC	VGNC:67497
Mus musculus	GTF2F1	MGD	MGI:1923848

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