2. Gene
  3. SLCO3A1 - solute carrier organic anion transporter family member 3A1 Gene

SLCO3A1 - solute carrier organic anion transporter family member 3A1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as OATPD; OATP-D; OATP3A1; OATPRP3; OATP-RP3; SLC21A11

Gene ID: 28232 | Gene type: protein coding

About SLCO3A1

Cytogenetic location: 15q26.1 Genomic coordinates (GRCh38): 15:91,853,708-92,172,435 (from NCBI)

This gene has 13 transcripts (splice variants), 264 orthologues and 10 paralogues. Broad expression in testis (RPKM 11.4), lung (RPKM 6.4) and 23 other tissues.

Summary

Predicted to enable sodium-independent organic anion transmembrane transporter activity. Involved in positive regulation of NF-kappaB transcription factor activity; positive regulation of protein phosphorylation; and prostaglandin transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLCO3A1 Products(2)

mRNA Protein Name
NM_001145044.1 NP_001138516.1 solute carrier organic anion transporter family member 3A1 isoform 2
NM_013272.4 NP_037404.2 solute carrier organic anion transporter family member 3A1 isoform 1

SLCO3A1 Protein Structure

OATP

OATP: Organic Anion Transporter Polypeptide (OATP) family (39 - 623)

Kazal_2

Kazal_2: Kazal-type serine protease inhibitor domain (477 - 527)

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  • 710 a.a.
Protein Preferred Names Protein Names

solute carrier organic anion transporter family member 3A1

PGE1 transporter

Related Diseases

Diseases Alias
Intestinal Perforation

Perforation Of Intestine
Primary Hypertrophic Osteoarthropathy

Pachydermoperiostosis Syndrome

Osteoarthropathy, Primary Hypertrophic

Pachydermoperiostosis Of Nail

Idiopathic Hypertrophic Osteoarthropathy

Pho
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13357 SLCO3A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SLCO3A1 RGD RGD:620227
Felis catus SLCO3A1 VGNC VGNC:65446
Canis familiaris SLCO3A1 VGNC VGNC:46497
Macaca mulatta SLCO3A1 VGNC VGNC:77598
Bos taurus SLCO3A1 VGNC VGNC:34953
Mus musculus SLCO3A1 MGD MGI:1351867