2. Gene
  3. P2rx1 - purinergic receptor P2X 1 Gene

P2rx1 - purinergic receptor P2X 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as P2XMR

Gene ID: 25505 | Gene type: protein coding

About P2rx1

Primary_assembly 10: 57,618,586-57,633,623 forward strand.mRatBN7.2:CM026983.1

This gene has 3 transcripts (splice variants), 199 orthologues, 6 paralogues and is associated with 1 phenotype. Biased expression in Lung (RPKM 76.9), Spleen (RPKM 54.) and 8 other tissues.

Summary

Enables several functions, including ATP binding activity; extracellularly ATP-gated cation channel activity; and suramin binding activity. Involved in several processes, including glutamatergic synaptic transmission; neuronal action potential; and regulation of cytosolic calcium ion concentration. Located in membrane raft; neuron projection; and plasma membrane. Part of protein-containing complex. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic active zone membrane. Orthologous to human P2RX1 (purinergic receptor P2X 1). [provided by Alliance of Genome Resources, Apr 2022]

P2rx1 Products(3)

mRNA Protein Name
NM_001285415.1 NP_001272344.1 P2X purinoceptor 1 isoform 3
NM_001142367.2 NP_001135839.1 P2X purinoceptor 1 isoform 2
NM_012997.3 NP_037129.1 P2X purinoceptor 1 isoform 1

P2rx1 Protein Structure

P2X

P2X: TIGR00863 (0 - 367)

  • 0
  • 100
  • 200
  • 300
  • 399 a.a.
Protein Preferred Names Protein Names

P2X purinoceptor 1

ATP receptor

P2X1

RP-2 protein

purinergic receptor P2X, ligand-gated ion channel, 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09897 P2RX1 Human Pre-designed siRNA Set A / Unkown
HY-RS09898 P2rx1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09899 P2rx1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2rx1 NCBI NCBI:5023