2. Gene
  3. MMD - monocyte to macrophage differentiation associated Gene

MMD - monocyte to macrophage differentiation associated Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MMA; MMD1; PAQR11

Gene ID: 23531 | Gene type: protein coding

About MMD

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:55,392,622-55,421,835 (from NCBI)

This gene has 4 transcripts (splice variants), 217 orthologues and 10 paralogues. Biased expression in fat (RPKM 97.6), brain (RPKM 27.2) and 9 other tissues.

Summary

This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages. [provided by RefSeq, Jul 2008]

MMD Products(1)

mRNA Protein Name
NM_012329.3 NP_036461.2 monocyte to macrophage differentiation factor

MMD Protein Structure

HlyIII

HlyIII: Haemolysin-III related (24 - 220)

  • 0
  • 100
  • 200
  • 238 a.a.
Protein Preferred Names Protein Names

monocyte to macrophage differentiation factor

macrophage maturation-associated

Related Diseases

Diseases Alias
Slate Pneumoconiosis

Schistosis
Spondyloepiphyseal Dysplasia, Maroteaux Type

Spondyloepiphyseal Dysplasia Maroteaux Type

Pseudo-Morquio Syndrome Type 2

Sed, Maroteaux Type

Brachyolmia Type 2

Pseudo-Morquio Syndrome, Type 2

Spondyloepiphyseal Dysplasia Of Maroteaux

Brachyolmia Maroteaux Type

SEDM

Sed Maroteaux Type

Dysplasia, Spondyloepiphyseal, Maroteaux Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08511 MMD Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08512 MMD2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus MMD VGNC VGNC:31512
Canis familiaris MMD VGNC VGNC:43270
Felis catus MMD VGNC VGNC:68277
Macaca mulatta MMD VGNC VGNC:74885
Mus musculus MMD MGD MGI:1914718
Rattus norvegicus MMD RGD RGD:1592079
Others MMD NCBI