PSTK - phosphoseryl-tRNA kinase Gene

Homo sapiens

Also known as C10orf89

Gene ID: 118672 | Gene type: protein coding

About PSTK

Cytogenetic location: 10q26.13 Genomic coordinates (GRCh38): 10:122,980,401-122,990,390 (from NCBI)

This gene has 9 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in bone marrow (RPKM 1.8), testis (RPKM 1.5) and 25 other tissues.

Summary

Predicted to enable kinase activity and tRNA binding activity. Predicted to be involved in phosphorylation; selenocysteinyl-tRNA(Sec) biosynthetic process; and translation. Predicted to act upstream of or within selenocysteine incorporation. [provided by Alliance of Genome Resources, Apr 2022]

PSTK Products(2)

mRNA	Protein	Name
NM_001363531.2	NP_001350460.1	L-seryl-tRNA(Sec) kinase isoform 1
NM_153336.3	NP_699167.2	L-seryl-tRNA(Sec) kinase isoform 2

PSTK Protein Structure

KTI12

0
100
200
300
348 a.a.

Protein Preferred Names

Protein Names

L-seryl-tRNA(Sec) kinase

O-phosphoseryl-tRNA(Sec) kinase

Related Diseases

Diseases

Alias

Keshan Disease

Caused By Deficiency Of Selenium In The Diet

Enlarged Heart And Poor Heart Function

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11344	PSTK Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PSTK	VGNC	VGNC:76335
Mus musculus	PSTK	MGD	MGI:2685945
Bos taurus	PSTK	VGNC	VGNC:33485
Felis catus	PSTK	VGNC	VGNC:64419
Canis familiaris	PSTK	VGNC	VGNC:45126
Rattus norvegicus	PSTK	RGD	RGD:1564300

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