Folic acid methyl ester

Cat. No.: HY-400648 Purity: 99.12%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Folic acid methyl ester is a methyl ester metabolite of folic acid that can be used in the study of neuropsychiatric conditions, such as depression^{[1]^.}

For research use only. We do not sell to patients.

Folic acid methyl ester Chemical Structure

CAS No. : 1348988-65-7

Size	Price	Stock	Quantity
5 mg	USD 390	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 630	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Folic acid methyl ester is a methyl ester metabolite of folic acid that can be used in the study of neuropsychiatric conditions, such as depression^{[1]^.}

Molecular Weight

455.42

Formula

C₂₀H₂₁N₇O₆

CAS No.

1348988-65-7

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=NC(CNC3=CC=C(C=C3)C(N[C@H](C(OC)=O)CCC(O)=O)=O)=CNC2=NC(N)=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (219.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1958 mL	10.9789 mL	21.9578 mL
5 mM	0.4392 mL	2.1958 mL	4.3916 mL
10 mM	0.2196 mL	1.0979 mL	2.1958 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.12%

Select Batch:

Data Sheet (265 KB) SDS (393 KB)

COA (245 KB) HNMR (435 KB) RP-HPLC (491 KB)

Handling Instructions (2659 KB)

References

[1]. Vuckovis, et al. Compositions and methods for treating depression. World Intellectual Property Organization, WO2018144088 A1. 2018-08-09.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1958 mL	10.9789 mL	21.9578 mL	54.8944 mL
	5 mM	0.4392 mL	2.1958 mL	4.3916 mL	10.9789 mL
	10 mM	0.2196 mL	1.0979 mL	2.1958 mL	5.4894 mL
	15 mM	0.1464 mL	0.7319 mL	1.4639 mL	3.6596 mL
	20 mM	0.1098 mL	0.5489 mL	1.0979 mL	2.7447 mL
	25 mM	0.0878 mL	0.4392 mL	0.8783 mL	2.1958 mL
	30 mM	0.0732 mL	0.3660 mL	0.7319 mL	1.8298 mL
	40 mM	0.0549 mL	0.2745 mL	0.5489 mL	1.3724 mL
	50 mM	0.0439 mL	0.2196 mL	0.4392 mL	1.0979 mL
	60 mM	0.0366 mL	0.1830 mL	0.3660 mL	0.9149 mL
	80 mM	0.0274 mL	0.1372 mL	0.2745 mL	0.6862 mL
	100 mM	0.0220 mL	0.1098 mL	0.2196 mL	0.5489 mL