1. GPCR/G Protein Neuronal Signaling
  2. Dopamine Receptor
  3. Fallypride precursor

Fallypride precursor (Compound 15) can be used for synthesis of Fallypride (HY-135497). Fallypride is an antagonist of the dopamine D2/D3 receptor. Fallypride can be used as a positron emission tomography (PET) radiotracer when labeled with 18F.

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Fallypride precursor Chemical Structure

Fallypride precursor Chemical Structure

CAS No. : 166173-74-6

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Description

Fallypride precursor (Compound 15) can be used for synthesis of Fallypride (HY-135497). Fallypride is an antagonist of the dopamine D2/D3 receptor. Fallypride can be used as a positron emission tomography (PET) radiotracer when labeled with 18F[1].

Molecular Weight

516.65

Formula

C27H36N2O6S

CAS No.
Appearance

Oil

Color

Light yellow to yellow

SMILES

C=CCN(CCC1)[C@@H]1CNC(C2=C(C(OC)=CC(CCCOS(=O)(C3=CC=C(C=C3)C)=O)=C2)OC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (387.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9355 mL 9.6777 mL 19.3555 mL
5 mM 0.3871 mL 1.9355 mL 3.8711 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9355 mL 9.6777 mL 19.3555 mL 48.3887 mL
5 mM 0.3871 mL 1.9355 mL 3.8711 mL 9.6777 mL
10 mM 0.1936 mL 0.9678 mL 1.9355 mL 4.8389 mL
15 mM 0.1290 mL 0.6452 mL 1.2904 mL 3.2259 mL
20 mM 0.0968 mL 0.4839 mL 0.9678 mL 2.4194 mL
25 mM 0.0774 mL 0.3871 mL 0.7742 mL 1.9355 mL
30 mM 0.0645 mL 0.3226 mL 0.6452 mL 1.6130 mL
40 mM 0.0484 mL 0.2419 mL 0.4839 mL 1.2097 mL
50 mM 0.0387 mL 0.1936 mL 0.3871 mL 0.9678 mL
60 mM 0.0323 mL 0.1613 mL 0.3226 mL 0.8065 mL
80 mM 0.0242 mL 0.1210 mL 0.2419 mL 0.6049 mL
100 mM 0.0194 mL 0.0968 mL 0.1936 mL 0.4839 mL
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Fallypride precursor Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Fallypride precursor
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HY-158243
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