2. GPCR/G Protein
  3. Adenosine Receptor
  4. Evodenoson

Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenoson’s primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenoson’s protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α).

For research use only. We do not sell to patients.

Evodenoson Chemical Structure

Evodenoson Chemical Structure

CAS No. : 844873-47-8

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Based on 1 publication(s) in Google Scholar

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Description

Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenoson’s primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenoson’s protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α)[1].

IC50 & Target

A2AR

 

Molecular Weight

499.52

Formula

C23H29N7O6
CAS No.
SMILES

O[C@H]1[C@@H](O[C@@H]([C@H]1O)C(NC2CC2)=O)N3C4=NC(C#CCC5CCN(CC5)C(OC)=O)=NC(N)=C4N=C3
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Evodenoson Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Evodenoson844873-47-8ATL 313 DE 112ATL313ATL-313DE112DE 112DE-112Adenosine ReceptorP1 receptorAntiinflammatory agentMyeloperoxidase inhibitorIntestinal fluid secretion inhibitionInhibitorinhibitorinhibit

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