2. Immunology/Inflammation
  3. PSMA
  4. DOTA-PSMA-EB-01

DOTA-PSMA-EB-01 (Compound LNC1003) is a specific inhibitor of PSMA (IC50= 10.77 nM).DOTA-PSMA-EB-01 enhances the uptake and retention time of 177Lu in tumors.

For research use only. We do not sell to patients.

DOTA-PSMA-EB-01 Chemical Structure

DOTA-PSMA-EB-01 Chemical Structure

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DOTA-PSMA-EB-01 Related Antibodies

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Description

DOTA-PSMA-EB-01 (Compound LNC1003) is a specific inhibitor of PSMA (IC50= 10.77 nM).DOTA-PSMA-EB-01 enhances the uptake and retention time of 177Lu in tumors[1].

Molecular Weight

1927.02

Formula

C87H113N15Na2O28S2
SMILES

CC1=C(C=CC(C2=CC(C)=C(C=C2)NC([C@@H](NC(CN3CCN(CCN(CCN(CC3)CC(O)=O)CC(O)=O)CC(O)=O)=O)CCCCNC(CCOCCOCCC(NC[C@H]4CC[C@@H](CC4)C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)CC5=CC=C6C=CC=CC6=C5)=O)=O)=O)=O)=C1)/N=N/C7=C(C8=C(C(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C8N)C=C7)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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DOTA-PSMA-EB-01 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DOTA-PSMA-EB-01LNC1003LNC 1003LNC-1003PSMAProstate-specific membrane antigenradioligandprostatic cancerInhibitorinhibitorinhibit

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