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  3. DiOC7(3)

DiOC7(3)  (Synonyms: 3,3'-Diheptyloxacarbocyanine iodide)

Cat. No.: HY-D1073
Handling Instructions

DiOC7(3) (3,3'-Diheptyloxacarbocyanine iodide) is a green membrane potential probe (Ex=450-490 nm, Em=510-520 nm). DiOC7(3) can be used to quantify the vascular densities.

For research use only. We do not sell to patients.

DiOC7(3) Chemical Structure

DiOC7(3) Chemical Structure

CAS No. : 53213-83-5

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Description

DiOC7(3) (3,3'-Diheptyloxacarbocyanine iodide) is a green membrane potential probe (Ex=450-490 nm, Em=510-520 nm). DiOC7(3) can be used to quantify the vascular densities[1].

In Vivo

Identification for tumour vasculature (frozen section):
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs)[1].
1. The dye is administered to murine via lateral tail vein injection at a dose of 1 mg/kg/ in 50 μL volume.
2. Animals are killed 5 min after dye administration, and tumors are immediately excised and frozen at - 20°C.
3. Frozen sections 10 μm in thickness are rewarmed to room temperature, allowed to air dry.
4. Image using a microscope with 100W mercury lamp illumination and an epifluorescence condenser (excited at 430-490 nm, emitted at 510-520 nm.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

600.57

Formula

C31H41IN2O2

CAS No.
Emission (Em)

510

Excitation (Ex)

475

SMILES

CCCCCCCN1/C(OC2=CC=CC=C12)=C/C=C/C3=[N+](CCCCCCC)C4=CC=CC=C4O3.[I-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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