(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide 

(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide (Compound 4) is a somatostatin analog with K_ds of 0.61, 11.05, 23.5, 1200 and >1000 nM for SSTR5, SSTR3, SSTR2, SSTR1 and SSTR4, respectively^[1].

Kd: 0.61 nM (SSTR5), 11.05 nM (SSTR3), 23.5 nM (SSTR2), 1200 nM (SSTR1), >1000 nM (SSTR4)^[1]

1046.26

C₅₀H₆₇N₁₁O₁₀S₂

340821-13-8

{d-Phe}-Cys-Phe-{d-Trp(N-Me)}-Lys-Thr-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7)

{d-Phe}-CF-{d-Trp(N-Me)}-KTCT-NH2 (Disulfide bridge: Cys2-Cys7)

CN(C([C@@H](NC([C@H](CSSC[C@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)C(N[C@H](C(N)=O)[C@H](O)C)=O)NC([C@H](N)CC2=CC=CC=C2)=O)=O)CC3=CC=CC=C3)=O)[C@@H]1CC4=CNC5=CC=CC=C45

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Nikiforovich GV, et al. Molecular modeling suggests conformational scaffolds specifically targeting five subtypes of somatostatin receptors. Chem Biol Drug Des. 2007 Mar;69(3):163-9.  [Content Brief]