2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. STING Endogenous Metabolite
  4. Cyclic GMP

Cyclic GMP (cGAMP) is an endogenous second messenger that triggers interferon production in response to cytoplasmic DNA. Cyclic GMP activates the stimulator of interferon genes (STING), activating a signaling cascade that leads to the production of type I interferons and other immune mediators.

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Cyclic GMP Chemical Structure

Cyclic GMP Chemical Structure

CAS No. : 7665-99-8

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Other In-stock Forms of Cyclic GMP:

Other Forms of Cyclic GMP:

Cyclic GMP Related Antibodies

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Description

Cyclic GMP (cGAMP) is an endogenous second messenger that triggers interferon production in response to cytoplasmic DNA. Cyclic GMP activates the stimulator of interferon genes (STING), activating a signaling cascade that leads to the production of type I interferons and other immune mediators[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

345.21

Formula

C10H12N5O7P
CAS No.
SMILES

O[C@@H]([C@H](N1C=NC2=C1N=C(N)NC2=O)O[C@@H]3CO4)[C@@H]3OP4(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cyclic GMP Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclic GMP7665-99-8STINGEndogenous MetaboliteStimulator of Interferon GenesTMEM173MITAERISMPYSInhibitorinhibitorinhibit

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