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UCP-1 Antibody

Cat. No.: HY-P81170
COA User Guide for Antibodies

UCP-1 Antibody is an unconjugated, approximately 33 kDa, rabbit-derived, anti-UCP-1 polyclonal antibody. UCP-1 Antibody can be used for: WB, ELISA, Flow-Cyt expriments in mouse, and predicted: human, rat, dog, cow, horse, rabbit, sheep background without labeling.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

UCP-1 Antibody is an unconjugated, approximately 33 kDa, rabbit-derived, anti-UCP-1 polyclonal antibody. UCP-1 Antibody can be used for: WB, ELISA, Flow-Cyt expriments in mouse, and predicted: human, rat, dog, cow, horse, rabbit, sheep background without labeling.

Background

Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. The related gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Gene ID

7350

Synonyms
Uncoupling Protein-1; UCP1; UCP 1; Mitochondrial brown fat uncoupling protein 1; mitochondrial brown fat uncoupling protein; SLC25A7; Thermogenin; UCP 1; UCP; Uncoupling protein 1; UCP1_HUMAN.
Molecular Weight

Predicted band size: 33kDa

Purity

affinity purified

Subcellular Location

Mitochondrion inner membrane; Multi-pass membrane protein.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Rabbit Polyclonal Antibody

Clonality

Polyclonal

Host

Rabbit

Reactivity

Mouse

Predicted Reactivity

Human, Rat, Dog, Cow, Horse, Rabbit, Sheep

Note: The predicted reactivity is for reference only, not as a product performance guarantee.
SwissProt ID

P12242

Dilution Ratio

WB: 1:500-2000;ELISA: 1:5000-10000;Flow-Cyt: 1μg /test

Application

WB, ELISA, FC

Appearance

Liquid

Formulation

Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

KLH conjugated synthetic peptide derived from human UCP-1: 101-200/307

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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UCP-1 Antibody
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HY-P81170
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