Phospho-MDM2 (Ser166) Antibody (YA1888)

Cat. No.: HY-P82143: FAQs
Data Sheet User Guide for Antibodies

Phospho-MDM2 (Ser166) Antibody (YA1888) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1888), targeting Phospho-MDM2 (Ser166), with a predicted molecular weight of 55 kDa (observed band size: 90 kDa). Phospho-MDM2 (Ser166) Antibody (YA1888) can be used for WB, IHC-P experiment in human, rat background.

For research use only. We do not sell to patients.

Size	Price	Stock
10 μL	$70	Ask For Quote & Lead Time
50 μL	$185	Ask For Quote & Lead Time
100 μL	$300	Ask For Quote & Lead Time

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Biological Activity
Technical Parameters
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Description	Phospho-MDM2 (Ser166) Antibody (YA1888) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1888), targeting Phospho-MDM2 (Ser166), with a predicted molecular weight of 55 kDa (observed band size: 90 kDa). Phospho-MDM2 (Ser166) Antibody (YA1888) can be used for WB, IHC-P experiment in human, rat background.
Background	The related gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. The related gene is itself transcriptionally-regulated by p53. Overexpression or amplification of The locus is detected in a variety of different cancers. There is a pseudorelated gene for The related gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Gene ID	4193
Synonyms	Double minute 2 protein; Hdm2; Oncoprotein Mdm2
Molecular Weight	Predicted band size: 55 kDa; Observed band size: 90 kDa
Purity	Affinity Purified
Conjugation	Non-conjugated
Modification	Phosphorylated
Research Field	Neuroscience
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Rat
SwissProt ID	Q00987
Dilution Ratio	WB: 1/500-1/1000;IHC: 1/50-1/100
Application	WB, IHC-P
Appearance	Liquid
Formulation	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthetic phosphopeptide corresponding to residues surrounding Ser166 of human MDM2
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

Phospho-MDM2 (Ser166) Antibody (YA1888) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospho-MDM2 (Ser166) Antibody (YA1888)

Biological Activity

Technical Parameters

Properties

Documentation

Phospho-MDM2 (Ser166) Antibody (YA1888) Related Classifications

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