PAX6 Antibody

Cat. No.: HY-P80978: FAQs
Data Sheet SDS COA User Guide for Antibodies

PAX6 Antibody is an antibody targeting to PAX6.

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
10 μL	$70	In-stock	Estimated Time of Arrival: December 31
50 μL	$185	In-stock	Estimated Time of Arrival: December 31
100 μL	$300	In-stock	Estimated Time of Arrival: December 31
250 μL		Get quote

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Biological Activity
Technical Parameters
Properties
Documentation

Description	PAX6 Antibody is an antibody targeting to PAX6.
Background	The related gene encodes paired box protein Pax-6, one of many human homologs of the Drosophila melanogaster related gene prd. In addition to a conserved paired box domain, a hallmark feature of The related gene family, the encoded protein also contains a homeobox domain. Both domains are known to bind DNA and function as regulators of related gene transcription. Activity of The protein is key in the development of neural tissues, particularly the eye. The related gene is regulated by multiple enhancers located up to hundreds of kilobases distant from The locus. Mutations in The related gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing results in multiple transcript variants encoding different isoforms. Interestingly, inclusion of a particular alternate coding exon has been shown to increase the length of the paired box domain and alter its DNA binding specificity. Consequently, isoforms that carry the shorter paired box domain regulate a different set of related genes compared to the isoforms carrying the longer paired box domain.
Tag	Free
Gene ID	5080
Synonyms	PAX6; AN2; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin
Molecular Weight	Calculated MW: 47 kDa; Observed MW: 47 kDa
Purity	Affinity Chromatography
Conjugation	Non-conjugated
Modification	Unmodified
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse, Rat
SwissProt ID	P26367
Dilution Ratio	WB: 1/500-1/1000; IHC: 1/50-1/100; IF: 1/50-1/200
Application	WB, IHC-P, ICC/IF
Appearance	Liquid
Formulation	Supplied in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthesized peptide derived from human PAX6.
Documentation	Select Batch: Data Sheet (234 KB) SDS (251 KB) COA (205 KB) User Guide for Antibodies (1077 KB)

PAX6 Antibody Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PAX6 Antibody

Biological Activity

Technical Parameters

Properties

Documentation

PAX6 Antibody Related Classifications

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