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  2. Primary Antibodies
  3. Monoclonal Antibodies Recombinant Antibodies
  4. Optineurin Antibody (YA3127)

Optineurin Antibody (YA3127)

Cat. No.: HY-P83382
User Guide for Antibodies

Optineurin Antibody (YA3127) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3127), targeting Optineurin, with a predicted molecular weight of 66 kDa (observed band size: 75 kDa). Optineurin Antibody (YA3127) can be used for WB, IHC-P experiment in human background.

For research use only. We do not sell to patients.

Size Price Stock
10 μL $70 Ask For Quote & Lead Time
50 μL $185 Ask For Quote & Lead Time
100 μL $300 Ask For Quote & Lead Time

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Description

Optineurin Antibody (YA3127) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3127), targeting Optineurin, with a predicted molecular weight of 66 kDa (observed band size: 75 kDa). Optineurin Antibody (YA3127) can be used for WB, IHC-P experiment in human background.

Background

The related gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphorelated genesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Gene ID

10133

Synonyms
NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP
Molecular Weight

Predicted band size: 66 kDa; Observed band size: 75 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Immunology

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human

SwissProt ID

Q96CV9

Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100

Application

WB, IHC-P

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

Recombinant protein of human Optineurin

Documentation

Optineurin Antibody (YA3127) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Optineurin Antibody (YA3127)
Cat. No.:
HY-P83382
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