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  4. Mast Cell Tryptase Antibody (YA1533)

Mast Cell Tryptase Antibody (YA1533)

Cat. No.: HY-P81788
User Guide for Antibodies

Mast Cell Tryptase Antibody (YA1533) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1533), targeting Mast Cell Tryptase, with a predicted molecular weight of 31 kDa (observed band size: ). Mast Cell Tryptase Antibody (YA1533) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock
10 μL $70 Ask For Quote & Lead Time
50 μL $185 Ask For Quote & Lead Time
100 μL $300 Ask For Quote & Lead Time

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Description

Mast Cell Tryptase Antibody (YA1533) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1533), targeting Mast Cell Tryptase, with a predicted molecular weight of 31 kDa (observed band size: ). Mast Cell Tryptase Antibody (YA1533) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

Background

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase related genes are clustered on chromosome 16p13.3. These related genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These related genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. The feature is characteristic of tryptases but is unusual in other related genes. The alleles of The related gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate related genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathorelated genesis of asthma and other allergic and inflammatory disorders.

Gene ID

7177

Synonyms
TPS1; TPS2; TPSAB1; TPSB1; MCP 7; Mast cell protease 7; Tryptase alpha 1
Molecular Weight

Predicted band size: 31 kDa

Purity

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Immunology

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

Q15661

Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IP: 1/50

Application

WB, IHC-P, IP

Appearance

Liquid

Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human Mast Cell Tryptase

Documentation

Mast Cell Tryptase Antibody (YA1533) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Mast Cell Tryptase Antibody (YA1533)
Cat. No.:
HY-P81788
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